Exam 3 - Osteomyelitis Flashcards

(41 cards)

1
Q

severe infection of the bone, bone marrow, and surrounding soft tissue

A

osteomyelitis

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2
Q

most common organism for osteomyelitis

A

Staphylococcus aureus

*educate: keep your nails short

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3
Q

indirect entry (hematogenous) risk factors

A

blunt trauma
GU, respiratory infection marked by vascular insufficiency disorder (infection spreads to the bone)
boys < 12 y/o

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4
Q

most common sites of osteomyelitis

A

vascular bones

  • pelvis
  • tibia
  • vertebrae
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5
Q

direct entry risk factors

*most common

A

open wounds

foreign body present (including artificial joints, plates, etc)

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6
Q

bone death occurs as a result of ___

A

ischemia

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7
Q

dead bone is aka

A

sequestrum

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8
Q

thin membrane on the outside of your bones

A

periosteum

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9
Q

part of the periosteum that continues to have blood supply forms new bone called ___

A

involucrum

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10
Q

if sequestrum does not resolve on its own or debrided a sinus tract develops. What occurs with a sinus tract?

A

chronic, purulent cutaneous drainage from the tract

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11
Q

acute osteomyelitis last how long

A

< 1 month

*initial infection

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12
Q

local s/sx of osteomyelitis

A
pain, worsens with activity; unrelieved by rest
swelling
tenderness
warmth
restricted movement
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13
Q

systemic s/sx of osteomyelitis

A
fever
night sweats
chills
restlessness
nausea
malaise
drainage (late)
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14
Q

how long does chronic osteomyelitis last

A

> 1 month

fails to respond to abx treatment; process of exacerbation and treatment

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15
Q

granulation tissue turns into

A

scar tissue > avascular > ideal site for microorganism growth > cannot penetrate abx

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16
Q

long term and most rare complications

A

septicemia
septic arthritis
pathologic fractures
amyloidosis

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17
Q

Dx studies for osteomyelitis

A
bone, soft tissue injury (definitive way to Dx)
blood, wound culture
WBC
ESR
CRP
CXR, MRI, CT scan
bone scan
18
Q

how long does it take for osteomyelitis to show on an XR?

A

10 days to weeks

19
Q

how long for IV abx therapy

A

4-6 weeks or as long as 3-6 months

20
Q

how are IV abx give at home

A

PICC (peripherally inserted central catheter)
port
CVAD (central venous access device; central line)

21
Q

IV abx used for osteomyelitis

A
PCN
naficillin( Nafcil)
neomycin
vancomycin
Keflex
cefazolin (Ancef)
cefoxitin (Mefoxin)
gentamycin (Garamycin)
tobramycin (Nebcin)
22
Q

PO abx used for chronic osteomyelitis or given after IV abx therapy

A

cipro

*6-8 weeks

23
Q

bone grafts may help restore __ __

24
Q

what can develop d/t achilles tendon contracture if the foot is not properly supported in a neutral position by splint or boot

25
what can occur to pts taking fluoroquinolone (cipro, levo)
tendon rupture
26
side effects of cefazolin (Ancef)
hives severe, watery diarrhea blood in stool throat, mouth sores
27
lengthy abx use can cause an overgrowth of what?
candida albicans | c. diff
28
hematogenous osteomyelitis
d/t blood infection
29
contagious-focused ostemomyelitis
d/t contaminated bone surgery r/t hardware, open fracture, traumatic injury
30
osteomyelitis with vascular insufficiency
d/t decrease perfusion: common in DM and PVD commonly affects the feet
31
any diabetic foot ulcer more than __ cm in diameter is highly suspicious for osteomyelitis
2 cm
32
are systemic s/sx constant with chronic osteomyelitis?
No, they may be reduced but local s/sx such as constant pain, swelling, warmth at site may be present.
33
should elective orthopedic sx be performed if the pt currently has an infection?
No, increased risk for osteomyelitis
34
surgical interventions to help reduce risk for osteomyelitis
prophylactic abx pre-op abx 24 hr post op D/C foley, drains ASAP aseptic wound care
35
MRI can detect ___ ___ ___ which is an early indication of osteomyelitis
bone marrow edema
36
which 2 scans are most helpful to identify the extent of infection
MRI | CT
37
sx treatment for chronic osteomyelitis includes extended abx use and which type of surgery?
sequestrectomy
38
what occurs during a dequestrectomy?
removal of enough involucrum to enable the surgeon to remove sequestrum
39
irritation does not extend beyond __ week and uses a ___ physiologic saline solution
1 week sterile saline solution
40
which technique is essential when changing dressing r/t osteomyelitis
sterile
41
what labs must be monitored to avoid adverse abx reaction
peak | trough