Exam 3 part 4 Flashcards Preview

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Flashcards in Exam 3 part 4 Deck (15):
1

attaches G residue to 5' end of mRNA

guanylyltransferase

2

location of guanylyltransferase

attached to CTD

3

after guanylyltransferase detaches

Cap-Binding Complex (CBC) attaches to 5' cap,
binds mRNA to CTD

4

before termination point of mRNA,
what binds to it

AAUAAA,
CPSF

5

at termination point of mRNA,
what binds to it

CA
CstF

6

average poly A tail length

250

7

after termination point of mRNA

GU-rich region,
degraded away in nucleus

8

creates poly A tail

Poly-A Polymerase (PAP)

9

attaches to poly A tail

Poly-A Binding Protein

10

splicing is carried out by

spliceosome

11

spliceosome is made of

5 snRNPs or snurps, and other proteins

12

snRNPs (snurps) are made of

snRNAs and proteins
U1, U2, U4, U5, U6

13

names of snurps

U1, U2, U4-U6, U5

14

explain the process in splicing

U1 attaches to 5' splice junction
BBP and U2AF attach to adenine
U2 replaces BBP and U2AF
U4-U6 and U5 "triple snRNP" come in and bring U1 and U2 together
U6 replaces U1
U1 and U4 release
splice is complete

15

U2, U5 and U6 make the

catalytic core