Exam I Flashcards
(88 cards)
physical barrier of skin is approx
2 (sq meters)
physical barrier of mucous membranes is apprx
400 (sq meters)
- prevents attachment of organisms
- contains many glycoproteins
- aids in clearing infections
mucus
components of innate immune system
monocytes
macrophases
neutrophils
dendritic cells
cells that kill and have antigen presentation
monocytes/macrophages
cells that are professional killers
neurtrophils
cells that are killers
natural killer cells
cells that antigen capture in one location and presentation in another
dendritic cells
of proteins that are produced by what organ in the complement system
20 proteins in liver
cells included in adaptive immune system
B cells
T cells
antibodies that don’t kill, but mark a target for destruction (OPSONIZE)
-use modular design
B cells
different types of T cells
T helper cells
T kiler cells
Regulatory T cells
type of design that B cells use to mix and match, cut and paste different DNA variations
modular design
What is required for T cell activation?
antigen presentation
cell types that present antigen to T cells
dendritic cells
macrophages
B cells
hormone like messengers (proteins) produced by certain immune cells, especially T helper cells, that communicate with other cells and affect immune response
cytokines
IL-1, IL-2, INFgamma, TNF are all examples of
cytokines
MHC proteins that are found on virtually ALL cells of the body; scanned by killer T cells
Class I MHC
MHC proteins that are typically found only on APC; displays what has been killed at battle site (external)
Class II MHC
50-70% of circulating WBC’s from myeloid lineage are
neutrophils
2 types of lineage in immune system
myeloid
lymphoid
20-40% of circulating WBC’s are from:
lymphoid lineage
functions of complement system:
opsonization (mark bad guys)
act as chemical signals to attract phagocytes
make MACs (membrane attack complexes)
system that requires activation through alternate, lectin or classical pathways
complement system