Exam II Flashcards
(152 cards)
Substance
Any natural or synthesized version of product that changes perception, thoughts, etc.
Substance intoxication
Experience of significant maladaptive behavioral and psychological symptoms
Substance withdrawal
Experience of physiological and behavioral symptoms due to the cessation or reduction of substance use
Withdrawal symptom tendencies
Often opposite of substance intoxication
Substance abuse
Maladaptive pattern, leading to >= 1 in 12 months, causing impairment of distress
[DRINK]
[DRINK]
Substance abuse
D: Dangerous use of substance (e.g. repeatedly driving after drinking)
RI: Role impairment (repeatedly missing class, work, etc.)
N: No respect for the law (multiple DUIs)
K: Keeps drinking in spite of social/interpersonal problems
Substance dependance
Maladaptive pattern leading to >= 3 of “TWO-6-PACK”
TWO-6-PACK
> = 3 = Substance dependance
T: Tolerance
W: Withdrawal (or use to avoid withdrawal)
O: Occupational, social or recreational activities given up or cut back
6: Nothing - placeholder :)
P: Persistent desire for drug or unable to cut back/control
A: Amount taken larger (in quantity or amount of time) than intended (i.e. excessive)
C: Continued use despite physical and psychological problems from the drug
K: Keep using - great deal of time spent acquiring, using or recovering from use
How does a person become dependent?
Brain’s pleasure pathway
Ventral Tegmental Area (VTA) > Nucleus Accumbens > Frontal Cortex
Track lined w/ dopamine receptors (affects movement, cognition, emotion, motivation, & feelings of pleasure)
Biological Theories of SUDs
- 50% of risk of alcohol dependence = genetic
- Not just 1 gene
- Not just genes
-Reward sensitivity
Reward sensitivity
- High sensitivity = greater risk for SUD
- Physiological markers make intoxication more or less enjoyable
Psychological Theories of SUDs
- Social learning theory
- Cognitive theory
- Personality theory
Social learning theory of SUDs
- Modeling of using/abusing behaviors
- Follow example of parents
- Using is acceptable
Cognitive theory of SUDs
- Positive expectations about using
- Lack of coping skills
- Use when upset
Personality theory of SUDs
- Impulsivity
- Sensation-seeking
- Anti-socal behavior
Sociocultural perspectives of SUDs
- cultural norms
- gender differences
- trauma
- economic factors
- peer influences
- family factors
Influence of SUDs in popular media
- 7/10 characters smoke
- 1/3 use drugs and alcohol
Treatments for SUDs
- Behavioral
- Cognitive
- Biological
Behavioral treatment for SUDs
- Avoidance of the stimulus
- Skills training
- Aversive conditioning
- Contingency management
Cognitive treatment for SUDs
Address faulty expectations or beliefs
Biological treatments for SUDs
- Anxiolytics, antidepressants & antagonists
- Methadone maintenance programs
Efficacy of SUD treatment
Available treatments are effective in helping ~ 1/3 of substance abusers remain abstinent for up to a year
What are the models/definitions of addiction not from neuroscience?
- Disease model = medication
- Choice model = learn to make better decisions
- Genetic disorder
- Self-medication
Marc Lewis: “Addiction = accelerated learning” & “Drive=craving”
Nature of the feedback loop in SUDs
Craving (drive) Synaptic growth (drug imagery)