Exam II Flashcards
(64 cards)
Substance Abuse
(DRINK) Dangerous use of substance, Role Impairment (missing work..), No respect for the law, Keeps drinking/using in spite problems
Substance Dependence:
TWO 6 PACK = Tolerance, Withdraw, Occupational, social, or recreational activities given up, 6, Persistent desire to drink, Amount taken in larger, Continued use despite problems, Keep using lots of time spend getting/recovering/using
Diagnosis for SZ
Delusions, Hallucinations, Disorganized Speech, Catatonic behavior, Negative Symptoms, Impairment in Social/Occupational functioning, Duration = continuous signs for at least 6 months
Schizophreniform Disorder
active SZ symptoms lasting 1-6 months then goes away
Schizoaffective Disorder
Active SZ symptoms + recurrent major depression or bipolar disorder
Delusional Disorder
Nonbizarre delusions lasting more than 1 month; no other significant impairment
Major Depressive Episode
Five or more of the following during a 2 week period: Depressed mood most of the day, every day
o Depressed Mood
o Anhedonia: diminished interest or pleasure in all activities
o Significant change in appetite and/or weight (gain or loss)
o Sleep disturbance (hypersomnia (excessive sleep) or insomnia)
o Psychomotor agitation (antsy, fidgety) or retardation (slowed movements, speech…)
o Fatigue/loss of energy
o Feelings of worthlessness or inappropriate guilt
o Decreased concentration or increased indecisiveness
o Recurrent thoughts of death
Dysthymia
Depressed most of the day, everyday for at least 2 years, and at least two of the following, can’t have no symptoms for more than 2 months in 2 years time o Appetite disturbance o Sleep disturbance o Low energy/Fatigue o Low Self-Esteem o Poor concentration/Indecisiveness o Feelings of hopelessness
Bipolar Disorder (Manic Depression)
Manic Episode: At least 1 week of persistently elevates, expansive or irritable mood, including more than or equal to 5 of the following (enough to cause marked impairment in functioning and/or hospitalization):
o Inflated self-esteem or grandiosity
o Decreased need for sleep
o Pressured speech (talking really fast)
o Racing thoughts
o Distractibility
o Increase in goal-directed activity or psychomotor agitation
o Excessive involvement in high-risk pleasure activities
Prevalence of SZ
0.5-2% of population is effected, most prevalent in homeless population ~200,000, women develop the disorder later have milder symptoms and have more favorable course than men do, possibly less severe in developing countries…, MZ twins 48% DZ twins 17%, people born in spring months
Biological Etiology of SZ
- Genetic: very strong evidence for hereditary factors
- MZ twins concordance rate = 48%
- DZ twins concordance rate = 17%
- Possibly one set of genes for (+) symptoms; another set of genes for (–) symptoms
Abnormalities of Brain Structure for SZ
- Enlarged ventricles (fluid-filled cavities); reduced volume, and neuron density in frontal cortex, and other brain abnormalities linked to cognitive and emotional deficits (neurocognitive disorder)
- Brain may not be fully developing in the right ways
Neurochemical Etiology of SZ
- Excess of dopamine; serotonin, GABA, and Glutamate may also play roles [for (-) symptoms]
- Increased DA receptors in Mesolimbic pathway (VTA & NA), DA is in these places, not everywhere, is great for reducing (+) symptoms
Neurodevelopmental Hypothesis for SZ
• Disruptions in normal maturation process of the brain before or at birth
Evidence:
• Nazi blockade of food in Netherlands, women who were in their 2nd trimester during this time = bump in babies that had SZ
• Influenza epidemic in Finland – 2nd trimester get flu = increase in SZ babies
o Birth Complications & Prenatal Viral Exposure for SZ
- Particularly those involving loss of oxygen that could damage brain
- More likely to have SZ when born during the Spring (esp. in boys, and left handed)
Etiology of Stress in SZ
- Plays a key role in triggering SZ break
* Relationships, work, academic, abuse, financial, etc
Genetic Factors for Dysthymia
- Multiple abnormalities strongly implicated
* Serotonin transporter gene abnormalities
o Substance
Any natural or synthetic product that changes perception, thoughts, behaviors, etc
o Substance Intoxication
experience of significant maladaptive behavioral and psychological symptoms (violent…)
o Substance Withdrawal
experience of physiological and behavioral symptoms due to the cessation or reduction of substance use
Substance Abuse
Maladaptive pattern leading to at most a month in 12 months causing impairment or distress (DRINK)
Substance Dependance
Maladaptive pattern leading to 3 or more of the TWO 6 PACK
o Tolerance
how much they need to get high/drunk increases
o Binge drinking
drinking 5 or more drinks within a couple of hours