Exam II Organogenetic Period Part II Flashcards
(118 cards)
Upper limbs appear day ____, lower limbs appear day ____.
26, 28
Limb development not complete until week ____.
8
Differentiation begins in the ____ of the lateral somatic mesoderm.
Mesenchyme
Each limb bud is made up of a ____ core covered by ectoderm.
Mesenchymal
The end of each limb bud is covered by a thickening of the ectoderm called the ____.
Apical ectoderm ridge
The apical ectodermal ridge produces signaling agents that control ____ development.
Limb
Limb buds first appear on the ____ portion of the body walls.
Anterior
Upper limb buds develop ____ lower (caudal) cervical somites.
Opposite
Limb buds begin slightly ____ than their final location due to cranial development.
Lower
Lower limb buds develop ____ the lumbar and upper sacral somites.
Opposite
Initially, upper and lower limb bud development is ____ but as development progresses, each become more specialized.
The same
Dermatome placement along limb bud has lower cervical ____.
Most distally.
Blood vessels and cartilage bone model develop from mesenchyme adjacent to the ____.
Apical ectodermal ridge
The apical ectodermal ridges ____ to form hand and foot plates.
Flatten
Week ____, the hands precede the feet by a couple of days.
5
The mesenchymal tissue in the hand and foot plates ____ to form digital rays.
Condense
Digital rays are the primordium of fingers and toes and are present by the end of week ____.
6
The apical ectodermal ridge ____ development of bones and the end of each digital rays.
Induces
Phalanges form from the apical ectodermal ridge with loose ____ tissue between the phalanges.
Mesenchymal
By the ____ week, the mesenchymal tissue between the phalanges deteriorates leaving individual fingers.
8th
Development of the appendicular skeleton coincides with mesenchymal tissue ____ to form chondrification centers beginning week 5.
Aggregation
A ____ skeleton in each limb is formed by the end of week 6.
Cartilaginous
____ of the long bones begins in week 7.
Osteogenesis (ossification)
The ____ is the first long bone to undergo osteogenesis.
Femur