EXERCISE AND HORMONES, ERGOGENIC AIDS, RECOVERY AND TAPERING RECOVERY Flashcards
(65 cards)
Neuro-endocrine have highly interactive and widespread roles in what systems
catabolism
brain structure and function
anabolism
cardiovascular system
defence and repair
Endocrine effects of exercise are complex
- the complexity must be appreciated
- many hormones impact multiple tissue types and have diverse effects, some are anabolic and some are catabolic
- peptides and amine hormones tends to act fast but steroids slower
- hormone profiles during and after exercise serve the bodys homeostatic needs now and anticipated. more of them break down as exercise is prolonged and when more motor units are activated
Endocrine System Overview
stimulus sent to a host organ there can then be 2 ways
- steroid hormone - carried on proteins, which are made on demand to a target cells, going straight into them with direct action then the responses happen
- peptide and amine hormones - which are mad in advance and travel freely to the target ells, but can only bind to the outside of the cell receptors which then stimulate the cell to have a response
Steroids vs Peptide Hormones Difference
steroids - enter straight through the cell membrane and binds to the nucleus which then stimulates a response through the nucleus
peptides - attach ti the cells surface receptors and act by second messengers
Second Messengers
intracellular compound that increase in concentration with binding of a hormones to its receptors and amplifies the cellular response
What do Hormones Do
transport across membrane
secretory activity
enzyme activity
protein synthesis
all having an exercise and nutrient effect
What determines hormonal activity
hormone concentration in blood
- rate of secretion and of inactivation or excretion
- quantity of transport protein
- plasma volume
activity
- depends how much of them are in the blood which is determine by how much you secrete. more hormones in the blood then mean they are more likely to bind with the receptors but also depends on ho many receptors are available
Hormone receptor interaction
- blood hormones levels
- number of target cell receptors
- affinity binding
Addiction to drugs
increase drugs and hormones has it effects on cells and receptors that give you addiction and then when you begin to regulate them better to continue to getting the same results you have to increase your intake
what dictates how you breathe
co2 via negative feedback control
in exercise feedback
your brain needs glucose so you don’t want insulin in the blood to remove the glucose so you suppress the parasympathetic system to keep glucose in the blood stream
exercise is so different to stress
slide 10 lecture 22 - look into it
Neuroendocrine pathways of catabolism
hypothalamus
releases and stops releasing factors to the
anterior pituitary
which releases
1. adrenal glands = stress hormones catabolic and stop the hypothalamus - exercise and stress
2. gonads = sex hormones anabolic - recovery
stress hormones
hypothalamus
either stop or release, releasing hormones
either stimulating or not hormones
stimulating
- cortisol from the adrenal cortex, the longer the exercise the more it is used. lifestyle/stress can impact cortisol on eercise
- ad/nor ad from the adrenal medualla - short intense exercise
- hormones
stress hormones are catabolic and supress
anabolism
what is important if you are trying maintain or gain muscle
exercise volume, recovery, feeding and life/total stress
hormones during exercise
all increase more break down apart from insulin which goes down as we won’t less as we won’t glucose to stay in our blood during exercise as we need to use it
Catecholamine Response to Exercise
fast response
increase 2-6 fold non linear
acts via 2nd messengers on the cell surface
has many effects
- immune metabolism
- hormones
- substrate
- pressor responses
Cardiovascular Effects of Catecholamines
increase blood pressure and redistribution
- increase venoconstriction, vasoconstriction, hr, ventricular contractility
training and catecholamine
training decrease catecholamine to a given intensity due to the stress but after training for a couple weeks it will hardly increase as you are use to it so less stress
as you get more trained you still have a stress release as you just train harder
Adrenaline Powerfully increeases
glycogenolysis
no linear response
the more stress the more ad we use to make glucose but we do’t wont this but we often have to if we run out of glucose
Mobilsation of FFAs spares ____ at mod intensity
glycogen to help maintain glucose
less FFA mobilisation with an increase of carb feeding
FFA Mobilisation and Exercise Intensity
decrease with heavy exercise
slide 20 lecture 22 go over
Prolonged Exercise and Fuels
- we gradually move through fuels as exercise continues
- rely more on whats in the blood not the muscle
- we use the fat being delivered to the cells
- depends on what and if you are eating and hormones
- muscles will use what you give it
Muscles will use what you …..
give it