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Flashcards in exotoxin producing bacteria Deck (13):
1

botulinum toxin
tetanus toxin

neurotoxins: interferes with neural transmission

2

shigella
vibrio cholerae

enterotoxins: affect intestine, cause H20 and electrolyte imbalance of intestinal epithelium → diarrhea

3

exotoxin that binds simultaneously to MHC II receptor and T cell receptor → allows for polyclonal expansion of T cells → release lots of cytokines

superantigen

4

s. aureus
s. pyogenes (group A strep)

superantigens causing shock

5

EHEC complication

shiga-toxin can cause HUS

6

hemolytic anemia
thrombocytopenia
acute renal failure

hemolytic uremic syndrome

7

7 bacteria that secrete enterotoxins: exotoxin that causes water + electrolyte imbalance of intestinal epithelium → diarrhea

vibrio cholerae
ETEC -heat labile toxin
s. aureus
shigella
yersinia
clostridium difficile
clostridium perfringens

8

exotoxin inactivates EF-2

corynebacterium diptheriae
pseudomonas (exotoxin A)

9

exotoxin activates Gs

vibrio cholerae
ETEC heat labile toxin

10

exotoxin disables Gi

pertussis toxin

11

exotoxin works via bacterial adenylate cyclase (no G protein involved)

Bacillus anthracis

12

exotoxin blocks GABA + glycine

clostridium tetani

13

toxins produced by s. pyogenes

streptolysin O: hemolysis on blood agar plate, oxygen labile
streptolysin S: oxygen stable
streptococcal pyrogenic exotoxins A, B, C = erythrogenic toxins = superantigens: associated with red rash + fever of scarlet fever and STSS