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Flashcards in ToRCHes infections Deck (19):
1

infection that passes from mother to infant during pregnancy or delivery
many cause congenital malformations: growth retardation, intellectual disability, hepatosplenomegaly, miscarriage, stillbirth

ToRCHes

2

ToRCHeS

Toxoplasma gondii
Other: parvovirus B19
Rubella
CMV
HIV, HSV-2
e
Syphilis

3

maternal infections that can cause neonatal meningitis

GBS
E.coli
Listeria monocytogenes

4

infections are more severe if:

primary infection during pregnancy

5

transmission: cat feces or undercooked meat

toxoplasmosis: toxoplasma gondii (protozoa)

6

congenital infection has this triad:
chorioretinitis
hydrocephalus
intracranial calcifications

toxoplasmosis: toxoplasma gondii (protozoa)

7

congenital infection:
infection of RBC precursors → severe fetal anemia, CV failure → hydrops fetalis (fluid accumulating in different parts of body: ascites, pleural effusions)

parvovirus B19

8

childhood infection:
"slapped cheek rash" →lacy reticular rash on chest and shoulders

erythema infectiosum (fifth disease): parvovirus B19

9

adult infection:
arthritis

parvovirus B19

10

children: mild fever + rash

rubella

11

congenital infection has this triad:
cataracts
PDA
sensorineural deafness
blueberry muffin" rash: areas of extramedullary hematopoiesis

rubella

12

adult: mononucleosis-like syndrome

CMV (most common)

13

congenital infection:
jaundice
hepatosplenomegaly
sensorineural hearing loss (witha mom who has mononucelosis-like syndrome)

CMV

14

concern of transmission during L&D (not pregnancy)

HIV and HSV

15

prevention of HIV transmission

HAART during pregnancy
if high viral load:
intrapartum zidovudine during delivery
C-section
after delivery: zidovudine prophylaxis to infant
AVOID breastfeeding

16

vesicular skin rash
conjunctivitis
pneumonia
CNS: meningoencephalitis
disseminated disease: sepsis

HSV

17

prevention of HSV transmission

suppression with acyclovir starting at 36 wks
if active genital infection at time of labor or prodromal sx: C-section

18

congenital infection:
early sx (onset during first 2 years of life)
hepatomegaly, elevated LFTs
rash followed by desquamation of hands and feet
snuffles: blood-tinged nasal secretions
skeletal abnormalities
late sx due to scarring/inflammation: (onset after first 2 years of life)
frontal bossing
interstitial keratitis (corneal scarring → blindness)
saddle nose deformity
hutchinson teeth (nothing of upper incisors)
perforation of hard palate
saber shins (anterior bowing of tibia)

syphliis

19

treatment of syphlis in pregnant patient with pen allergy?

#1 desensitize patient
#2 penicllin G (best treatment)