Female Repro Flashcards
(149 cards)
what do you call the first menses wherein the reproductive system undergoes monthly changes in structure and function?
menarche
what do you call the stage wherein the ovaries completely stop producing reproductive hormones?
cyclic changes become irregular and eventually disappear
Menopause
what do you call the simple cuboidal epithelium of the ovary that is continuous with the mesothelium and overlying a layer of dense connective tissue capsule?
surface (germinal) epithelium
what do you call the dense connective tissue capsule of the ovary similar to the testis?
tunica albuginea
what do you call the ovary layer which is a region with a stroma of highly cellular connective tissue and many ovarian follicles?
cortex
what do you call the most internal part of the ovary which contains loose CT and blood vessels entering the organ through the hilum?
medulla
what do you call the cells that undergo mitosis to produce oogonia?
primordial germ cells
the first meiosis of the oogonia is arrested and will continue later on during puberty, what do you call the cells in arrest?
nagstop sa prophase 1
primary oocyte
this happens b4 birth ha
An ____ consists of an oocyte surrounded by one or more layers of epithelial cells within a basal lamina.
ovarian follicle
what do you call the follicles formed during fetal life?
or primary oocyte enveloped by a single layer of flat follicular cells
primordial follicles
Prompted by FSH, oocyte differentiation includes formation of secretory granules called what? these lie just inside an oocyte’s plasma membrane, undergo exocytosis early in fertilization and contains proteases
cortical granules
Follicular cells undergo mitosis and form a simple cuboidal epithelium around the growing oocyte. The follicle is now called?
unilaminar primary follicle
Note: Follicular cells surround the primordial follicle and are not primordial follicles themselves. Primordial follicles = primary oocyte + single layer of flattened follicular cells
what do you call the stratified follicular epithelium in which cells communicate through gap junctions? what do you call the cells in this epithelium?
this epithelium is present after follicular cells continue to proliferate
granulosa; granulosa cells
what do you call the follicle that is being surrounded by granulosa cells?
this is what u call the follicle after follicular cells proliferete
multilaminar primary follicle
this is still avascular and surrounded by a basement membrane
what do you call the extracellular material that accumulates in between the primary oocyte and the growing primary follicle?
zona pellucida
where in the primary follicle can you find ZP3 and ZP4 components which are important sperm receptors binding specific proteins on the sperm surface and inducing acrosomal activation?
zona pellucida
what do you call the condition wherein growing primary follicles become enlarged and filled with numeroud cysts and an anovulatory state (no follicles completing maturation successfully)?
polycystic ovary syndrome (PCOS)
this is a common cause of infertility in women
stromal cells immediately outside growing primary follicle differentiate to form the ____ which is divided into two distinct tissues that surround the primary follicle.
theca or follicular theca
what is the identifiable difference between a primordial follicle and a unilaminar primary follicle?
- primordial follicle = flattened follicular cells arnd follicle (meaning squamous epithelium siya)
- unilaminar primary follicle = simple cuboidal epithelium arnd follicle
what do you call the theca that is well-vascularized with typical steroid-producing cells secreting androstenedione?
theca interna
what do you call the molecule that diffuses into the follicle through the basement membrane and is converted by granulosa cells through an enzyme called aromatase?
androstenedione
what do you call the estrogen that returns to the theca and stroma around the follicle from the granulosa cells and will be distributed throughout the body, inducing the changes characteristic of puberty?
this came from androstenedione and is converted by granulosa cells through aromatase
estradiol
what are the two distinct tissues or types of theca that surrounds the follicle?
- theca externa
- theca interna
this is the theca with fibroblasts and smooth muscle merges gradually with the surrounding stroma
theca externa