Female Reproductive #2 Flashcards Preview

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Flashcards in Female Reproductive #2 Deck (15):
1

How is negative feedback to LH exerted in Luteal Phase?

⬆️Progesterone

2

How is negative feedback to FSH exerted in LUTEAL PHASE?

INHIBIN B!!

3

This part of the menstrual cycle is ALWAYS CONSTANT?

1. LUTEAL (15 days)

4

Order of estrogen potency?

Estradiol > Estrone > Estriol

5

Primary estrogen secreted by the ovarian follicule?

Estradiol

6

Main estrogen converted peripheraly by aromatase and its the predominant estrogen in menopause?

Estrone

7

Estrogen produced by the placenta from circulating androgens?

Estriol

8

Main clinical signs of Polycystic Ovarian Syndrome ?

1. Infertility
2. Hirsutism
3. Obesity
4. Insulin resistance
5. Amenorrhea/Oligo

9

Main hormones elevated in PCOS?

1. ⬆️LH
2. ⬆️DHEA

10

In PCOS, why is FSH suppressed?

1. ⬆️Levels of estrone (weak estrogen) —> ⬇️FSH

11

Mainly, why is there ⬆️Androgens in PCOS?

⬇️Aromatase activity —> ⬆️androgens and ⬇️estrogen

12

How to differentiate hirsutism of Adrenal from ovarian origin?

1. Dexamethasone test—> ⬇️DHEA (Adrenal)

13

When does pregnancy usually occur?

8-25 hours after ovulation

14

When does implantation usually occur?

5-7 days after fertilization

15

LH and hCG have similar activity, why?

They share same Beta-subunit