Female Reproductive #3 Flashcards Preview

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Flashcards in Female Reproductive #3 Deck (13):
1

What are the 3 different hormonal stages that maintain the Endometrium?

1. Luteal Phase (before implantation)
2. Implantation - 2nd month
3. 3rd Month - Term

2

Main hormones involved in the maintenance of the Endometrium in the Luteal Phase ?

1. ⬆️LH—> ⬆️⬆️progesterone and ⬆️estradiol

CORPUS LUTEUM

3

Main hormones involved in the maintenance of the Endometrium from implantation to 2nd month?

Placenta: ⬆️hCG —> ⬆️Corpus LUTEUM —> ⬆️⬆️progesterone/⬆️estradiol

4

How is progesterone secretion maintained from the 3rd month to term?

1. LDL delivered to Placenta

5

How is estrogen production maintain from 3rd month to term?

⬆️ Fetal Adrenal Androgens —> ⬆️DHEA —> FETAL LIVER —> ⬆️Androstenedione and ⬆️Testosterone —> PLACENTA AROMATASE —> ⬆️Estriol

6

Main function of hPL (human placental lactogen) ?

⬆️Glucose availability for the Fetus

7

hPL mechanism of action?

1. ⬆️Gluconeogenesis and ⬆️Glycogenolysis
2. ⬆️Insulin Resistance
3. ⬆️Glucose available for fetus

8

Why is glucosuria normal in pregnancy?

1. ⬆️GFR
2. ⬆️Insulin resistance

9

Why is the pituitary gland enlarged during pregnancy?

1. ⬆️ Estrogen —> ⬆️Lactotroph Cells —> ⬆️Prolactin

10

Why is there fluid retention and hemodilution in pregnancy?

1. ⬆️RAAS activity

11

Main physiologic mechanism in spontaneous abortion?

1. Death of Fetus —> ⬆️PGD’s —> ⬆️Contractions —> ABORTION

12

What hormones keep from overproduction of milk during pregnancy?

⬆️Estrogen and ⬆️Progesterone —> ⬇️Milk Synthesis

13

This hormone is inhibited during lactation to ⬆️prolactin synthesis and release ?

2. ⬇️Dopamine