Fibrous Xanthomas and Paget's Flashcards Preview

Diagnostic Imaging II Exam Three > Fibrous Xanthomas and Paget's > Flashcards

Flashcards in Fibrous Xanthomas and Paget's Deck (38)
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1

What conditions make up the group of fibrous xanthomas in order from smallest to largest?

Fibrous cortical defect, nonossifying fibroma, fibrous dysplasia

2

What is unique about the specific placement of a fibrous cortical defect in bone?

Loves cortex

3

What other lesion loves the cortex of bone like a fibrous cortical defect?

Osteoid osteoma

4

What is the treatment for a fibrous cortical defect or nonossifying fibroma?

Nothing because they usually regress over a 2-5 year period

5

How does a fibrous cortical defect look different than an osteoid osteoma?

No nidus or cortical thickening with FCD

6

What is the age range for a nonossifying fibroma?

8-20 years old (most occur in second decade aka teens)

7

How common are nonossifying fibromas?

30-40% of children

8

What is the specific part of bone where we find nonossifying fibromas?

Eccentric and metadiaphyseal

9

What are the common locations for nonossifying fibromas?

Long bones of lower extremity like distal tibia and distal femur

10

Why are fractures more possible with a nonossifying fibroma compared to a FCD?

Larger than a FCD (same with fibrous dysplasia)

11

What is the age range for fibrous dysplasia?

1-2 decades of life

12

Is fibrous dysplasia most commonly monostotic or polyostotic?

Monostotic (involving one bone)

13

Polyostotic fibrous dysplasia is seen with what type of condition that is also associated with Coast of Maine cafe au lai spots and precocious puberty in females?

McCune-Albright Syndrome

14

What radiographic finding is associated with fibrous dysplasia?

Rind sign

15

What is the term for the area of thickened sclerosis along the rim of a lesion of fibrous dysplasia?

Rind sign

16

What appearance occurs with the internal matrix involving fibrous dysplasia?

"Ground glass" appearance

17

What deformities can arise in the femur/tibia from fibrous dysplasia?

Saber shin and/or shepard's crook deformities

18

How common is Paget's disease?

3% of population over 40 years old

19

In what area of the world is Paget's more common?

Norther latitudes and specifically UK, Australia, New Zealand

20

What is the age range for Paget's?

Over 60

21

What is thought to be the cause of Paget's?

Virus

22

How does bone change overall from Paget's disease?

Increased resorption followed by increased bone formation which has a disorganized trabecular pattern lending to bone softening (bone increases in size and gets very white)

23

What are some of the more common areas for Paget's?

Pelvis, lumbar/thoracic spine, proximal femur, calvarium..

24

What are the lab findings seen with Paget's?

Increased hydroxyproline and alkaline phosphatase with normal serum calcium and phosphorus levels

25

"Cotton wool" appearance is associated with what lesion?

Paget's (in path we called it the "fuzzy pelvis")

26

What are the 4 stages of Paget's disease?

1 lytic/destructive 2 mixed 3 sclerotic/ivory 4 malignant degeneration and possible change to osteosarcoma

27

Paget's disease can lead to what serious change in the skull?

Basilar invagination with foraminal encroachment (due to bone softening)

28

What is the term for the well defined lysis of the frontal and occipital regions?

Osteoporosis circumscripta

29

What are the initial patient symptoms with Paget's?

None really...except maybe hats are feeling tighter (due to cortical thickening)

30

At what specific part of bone does Paget's begin in in long bones?

Subarticular end of bone (diff dx with GCT and chondroblastoma)