Primary Malignancies Flashcards Preview

Diagnostic Imaging II Exam Three > Primary Malignancies > Flashcards

Flashcards in Primary Malignancies Deck (58)
Loading flashcards...
1

What is the most common primary malignancy?

MM (27%) (then osteosarcoma then chondrosarcoma then Ewing's)

2

Which primary malignancy is a proliferation of plasma cells which infiltrate the bone marrow?

MM

3

What is the age range for MM?

5-8th decade (75% are of ages 50-70 years)

4

Which gender is more likely to have MM?

Males

5

Which is more common: MM or metastasis?

Still metastasis....

6

Which two bone tumors are the only ones that are more common in females compared to males?

Hemangiomas and aneurysmal bone cyst ("bloody ones")

7

What is the most common cause of death in patients with MM?

Recurrently bacterial infections

8

What is the primary rad finding for MM?

Deossification of bone

9

What is the usual presentation of a bone scan in those with MM?

Negative

10

What are some laboratory findings that can be seen with MM?

Elevated ESR, plasma proteins, serum calcium, and serum phosphorus with thrombocytopenia, and rouleaux formation

11

What is the rouleaux formation that is commonly seen with MM?

Stacks or aggregates of RBCs seen on blood smear

12

What protein finding is commonly seen in 80-90% of those with MM?

Protein electrophoresis with "M-spike"

13

Detection of which protein in the urine can be found in 40% of MM patients?

Bence Jones proteins

14

What is the best test for MM besides the obvious biopsy?

M-spike protein electrophoresis

15

What are the common locations for a solitary plasmacytoma?

Vertebra > pelvis > skull > sternum > ribs

16

What is the term for a tumor that is a localized form of plasma cell proliferation?

Solitary plasmacytoma

17

How does a solitary plasmacytoma typically present?

Soap bubbly, highly expansile lesion

18

What is unique about the expansion of a solitary plasmacytoma in what it chooses to spare?

Posterior elements (of vertebrae)

19

What radiographic sign on an PA chest film can indicate a possible solitary plasmacytoma?

Extrapleural sign

20

What is an extrapleural sign?

Something in the pleural space pushing lungs inward

21

What type of thoracic spine change can be seen with solitary plasmacytomas of multiple levels?

Gibbus formation

22

What is the Gibbus formation?

Acute angular kyphotic thoracic spine changes causing wedges (think multiple solitary plasmacytomas)

23

"Rain drop skull" is associated with which neoplasm?

Multiple Myeloma

24

What is the best imaging used to detect MM?

Conventional radiography

25

How can an MRI help detect MM?

Marrow changes (2nd best test)

26

What is the cause of the appearance of a "rain drop skull" seen with MM?

Multiple holes of various sizes in the skull

27

In only what specific location of the body is cortical thinning considered a normal pattern of aging?

Deltoid tuberosity of the humerus

28

What type of MRI is best to be used for MM detection?

STIR (contrast enhanced T1)

29

What is usually the prognosis for MM?

Poor (5 year survival 20%)

30

Which tumor is a primary malignant tumor of undifferentiated connective tissue which forms neoplastic osteoid and is also the second most common primary malignant bone tumor overall?

Osteosarcoma