Final

Question 1

Molecules involved in the conversion of oxidized protein to their functional reduced suylfhydryl form include all of the following except

A) Thioredoxin

B) NADPH

C) Catalase

D) Thioredoxin reductase

E) None of the above are correct

Answer 1

Catalase

Question 2

All of the following are components of the electron transport chain except ______.

A) Coenzyme Q

B) Succinate dehydrogenase

C) Coenzyme A

D) Cytochrome C

E) NADH dehydrogenae

Answer 2

Coenzyme A

Question 3

The ETC component that transfers electrons directly to oxygen is __________.

Answer 3

Cytochrome oxidase

Question 4

During the oxidation of NADH there are several steps in which ∆E_^o’ is sufficient for ATP synthesis. These occur within

Answer 4

Complexes I, III and IV

Question 5

Which of the following molecules inhibits Complex I of the electron transport chain?

Answer 5

Amytal

Question 6

ATP synthesis and mitochondrial electron transport are coupled by

Answer 6

Protonmotive force & Proton gradient

Question 7

Evidence supporting the chemiosmotic theory inculdes all of the following except

Answer 7

The pH of a weakly buffered suspension of mitochondria rises when O2 added.

Question 8

Examples of uncouplers include ________.

Answer 8

DNP & Gramicidin

Question 9

In the ATP Synthase the F_o factor

Answer 9

Has three types of subunits & In a transmembrane proton channel

Question 10

The maximum P/O ration of FADH2 is

Answer 10

1,5

Question 11

The control of aerobic respiration by _________ is referred to as respiratory control.

Answer 11

ADP

Question 12

The first ROS formed during the reduction of oxygen is ________.

Answer 12

Superoxide radical

Question 13

The reaction of Fe+2 with H2O2 results in the production of

Answer 13

Hydroxyl radical & Hydroxide ion

Question 14

ROS are generated during

Answer 14

Xenobiotic metabolism, Respiratory burst, & Ionizing radiation

Question 15

Glutathione peroxidase

Answer 15

Converts organic peroxides into alcohols & Reduces H2O2 into H2O

Question 16

The NADPH required for the generation of GSH from GSSG in synthesized by the reactions of

Answer 16

The pentose phosphate pathway

Question 17

Glutathione peroxidase requires _____ for full activity

Answer 17

Selenium

Question 18

Examples of antioxidants include all of the following except _________

Answer 18

Gramicidin

Question 19

One of the mechanisms by which vitamin C protects membrane is by

Answer 19

Regenerating reduced α-tocopherol & Reacting with peroxyl radicals

Question 20

The ultimate electron acceptor of the mitochondrial electron transport system is

Answer 20

O₂& H₂O

Question 21

In Complex I of the ETC, the major sources of NADH include

Answer 21

Fatty acid oxidation & The citric acid cycle

Question 22

In Complex III, electrons are tranferred from UQH₂ to

Answer 22

Cytochrome c

Question 23

___________ is a metal cofactor of the cytochromes.

Answer 23

Fe

Question 24

Carbon monoxide inhibits which of the following?

Answer 24

Cytochrome oxidase

Question 25

Which of the following is the best reducing agent?

Answer 25

NADH

Question 26

The final product of oxidative phosphorylation is \_\_\_\_\_\_\_\_.

Answer 26

ATP

Question 27

\_\_\_\_\_\_\_\_\_\_\_\_\_ are hydrophobic molecules that dissipate ionic gradients.

Answer 27

Ionophores

Question 28

The return of ______ into the mitochondrion is coupled to the formation of \_\_\_\_\_\_.

Answer 28

H⁺/ATP

Question 29

The energy that is captured by the electron transport system is in the form of

Answer 29

NADH & FADH₂

Question 30

Reducing power generated in the cytoplasm can be transferred into the mitochondrion by which of the following processes?

Answer 30

Glycerol phosphate shuttle & Malate-aspartate shuttle

Question 31

The cytochromes contain which type of prostheic group?

Answer 31

Heme

Question 32

The function of complex III is the transfer of electrons from

Answer 32

Coenzyme Q to Cyt c

Question 33

Which of the following complexes contain copper?

Answer 33

Complex IV

Question 34

Which of the following acts as an allosteric inhibitor of complex IV?

Answer 34

ATP

Question 35

Which of the following is not a step in the ATP synthesizing process?

Answer 35

The O conformation binds ADP and Pi

Question 36

Nonshivering thermogenesis is regulated by which of the following?

Answer 36

Norepinephrine

Question 37

The primary function of catalase is to

Answer 37

Convert hydrogen peroxide to water

Question 38

How many ATP are generated during the oxidation of one NADH?

Answer 38

2.5

Question 39

Which of the following would not be classified as a ROS?

Answer 39

Hydroxide ion

Question 40

The principle sources of electrons for the electron transport system is (are) which of the following ## Footnote A) Glycolysis B) Citric acid cycle C) Fatty acid oxidation D) Both A and B are correct E) All of the above are correct

Answer 40

All of the above are correct