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Flashcards in Final Deck (40)
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1

Molecules involved in the conversion of oxidized protein to their functional reduced suylfhydryl form include all of the following except

A) Thioredoxin

B) NADPH

C) Catalase

D) Thioredoxin reductase

E) None of the above are correct

Catalase

2

All of the following are components of the electron transport chain except ______.

A) Coenzyme Q

B) Succinate dehydrogenase

C) Coenzyme A

D) Cytochrome C

E) NADH dehydrogenae

Coenzyme A

3

The ETC component that transfers electrons directly to oxygen is __________.

Cytochrome oxidase

4

During the oxidation of NADH there are several steps in which ∆Eo’ is sufficient for ATP synthesis. These occur within

Complexes I, III and IV

5

Which of the following molecules inhibits Complex I of the electron transport chain?

Amytal

6

ATP synthesis and mitochondrial electron transport are coupled by

Protonmotive force & Proton gradient

7

Evidence supporting the chemiosmotic theory inculdes all of the following except

The pH of a weakly buffered suspension of mitochondria rises when O2 added.

8

Examples of uncouplers include ________.

DNP & Gramicidin

9

In the ATP Synthase the Fo factor

Has three types of subunits & In a transmembrane proton channel

10

The maximum P/O ration of FADH2 is

1,5

11

The control of aerobic respiration by _________ is referred to as respiratory control.

ADP 

12

The first ROS formed during the reduction of oxygen is ________.

Superoxide radical

13

The reaction of Fe+2 with H2O2 results in the production of 

Hydroxyl radical & Hydroxide ion

14

ROS are generated during

Xenobiotic metabolism, Respiratory burst, & Ionizing radiation

15

Glutathione peroxidase

Converts organic peroxides into alcohols & Reduces H2O2 into H2O

16

The NADPH required for the generation of GSH from GSSG in synthesized by the reactions of 

The pentose phosphate pathway

17

Glutathione peroxidase requires _____ for full activity

Selenium

18

Examples of antioxidants include all of the following except _________

Gramicidin

19

One of the mechanisms by which vitamin C protects membrane is by

Regenerating reduced α-tocopherol & Reacting with peroxyl radicals

20

The ultimate electron acceptor of the mitochondrial electron transport system is

O& H2O

21

In Complex I of the ETC, the major sources of NADH include

Fatty acid oxidation & The citric acid cycle

22

In Complex III, electrons are tranferred from UQH2 to 

Cytochrome c

23

___________ is a metal cofactor of the cytochromes.

Fe

24

Carbon monoxide inhibits which of the following?

Cytochrome oxidase

25

Which of the following is the best reducing agent?

NADH

26

The final product of oxidative phosphorylation is ________.

ATP

27

_____________ are hydrophobic molecules that dissipate ionic gradients.

Ionophores

28

The return of ______ into the mitochondrion is coupled to the formation of ______.

H+/ATP

29

The energy that is captured by the electron transport system is in the form of 

NADH & FADH2

30

Reducing power generated in the cytoplasm can be transferred into the mitochondrion by which of the following processes?

Glycerol phosphate shuttle & Malate-aspartate shuttle