Final Flashcards

(39 cards)

1
Q

What is Heart Failure?

A

insufficient cardiac output

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2
Q

Sympathetic response to ACUTE dec. in cardiac output

A

+ inotrope, + chronotrope, vasoconstriction

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3
Q

Endocrine response to CHRONIC dec. in cardiac output

A

Renin-angiotensin-aldosterone system => inc. circulatory volume and venous return

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4
Q

Dilated Cardiomyopathy: Sympathetic Response => results

A

inc. peripheral resistance => inc. effort;
inc. HR => dec. diastole;
dec. cardiac output + RAAS => pulmonary edema

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5
Q

Chronic Valve Dz: Cause

A

failure of valve => regurgitation

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6
Q

Chronic Valve Dz: Sympathetic Response => Results

A

Na + water retention => inc. preload => pulmonary edema;

angioconstriction => inc. aortic resistance => inc. regurgitation

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7
Q

Hypertorphy: Causes

A

tension in heart muscle, angiotensin II (supports but not improves)

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8
Q

Hypertrophy: Types

A

Pressure Overload, Volume Overload

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9
Q

What type of hypertrophy is seen with Pressure Overload?

A

Concentric Hypertrophy

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10
Q

What form of hypertrophy is seen with Volume Overload?

A

Eccentric Hypertrophy

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11
Q

What the difference between Concentric and Eccentric hypertrophy?

A

Concentric => inc. myocyte size;

Eccentric => inc. in myocyte length

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12
Q

Left-Sided Congestive Heart Failure: Results

A

Hypotension => inc. HR, pulse weakness, syncope, azotemia;

Pulmonary Edema => dyspnea, tachypnea, exorcise intolerance, cyanosis

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13
Q

Right Sided Congestive Heart Failure: Results

A

General edema

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14
Q

Cardiac Cachexia: Results

A

anorexia, immobility, congestion of GI, hyperventilation

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15
Q

Upper Motor Neuron Signs

A

paralysis, normal/accentuated reflexes, normal/inc. muscle tone, min. muscle atrophy

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16
Q

Lower Motor Neuron Signs

A

Parlysis, a/hypoflexia, muscular hypotonia, rapid muscle atrophy

17
Q

Order of declining Mental status

A

Alert -> depression -> stupor -> coma

18
Q

Major types of Vascular Shunts

A

Arterio-venous and Portosystemic

19
Q

What is an Arterio-venous fistula/malformation?

A

direct communication between artery and vein that bypasses capillary bed

20
Q

Arterio-venous Fistula/Malformation: Etiology

A

congenital, traumatic, iatrogenic

21
Q

AV Fistula: Most Common Site

22
Q

AV Fistula: Pathophysiology

A

Inc. CO, HR, absolute blood volume;

Dec. total peripheral resistance

23
Q

What is Patent Ductus Arteriosus?

A

blood in the aorta re-enters pulmonary circulation

24
Q

What is Ventricular Septal Defect?

A

hole in the wall between the 2 ventricles

25
What is Eisenmenger Syndrome?
inc. pulmonary circulation => pulmonary hypertension; | reversal of flow through shunt.
26
Portosystemic Shunts: Types
Congenital, acquired, portal vein hypoplasia/atresia, hepatic arteriovenous malformations
27
What is an Extrahepatic shunt?
blood flow completely bypasses liver
28
What is an Intrahepatic Shunt?
portal vein branch communicates directly with hepatic vein branch
29
Portal Vein Hypoplasia: Forms
Idiopathic noncirrhotic portal hypertension, Portal vein hypoplasia-microvascular dysplasia
30
Portosystemic Shunts: Results
hypoglycemia, hyoalbuminemia, hypocholesterolemia, hypokalemia, dec. clotting factors, stunted growth, hyperammonemia
31
Pre-hepatic Liver Dz: Causes
hemolysis w/ hypoxia, necrosis, microthrombi mediated hepatopathy
32
Hepatic Liver Dz: Causes
toxin, infection, immune-mediated, Cu storrage
33
Post-hepatic Liver Dz: Causes
obstruction, tumor
34
Liver Function Tests
ammonia tolerance test, bile acid stimulation test
35
Growth Hormone: Functions
growth, protein metabolism, fat metabolism, carb metabolism
36
Growth Hormone: Stimulants
hypoglycemia, trauma, stress, exercise, gonadotropins, deep sleep, GHRH
37
Growth Hormone: Inhibitors
Hyperglycemia, aging, obesity, GHIH, somatomedins
38
Growth Hormone: Abnormalities
Pituitary Dwarfism, acromegaly (secretory tumor)
39
GI Obstruction: Signs
pain, distention, tympany, dec. motility, dehydration, vomiting/NG reflux (horse)