Final: Cancers

Question 0

Most common tumor of the heart

Answer 0

Atrial myoxoma

Question 1

Hypocellular myoxoid mass with polygonal or elongated cells. Mononuclear or multi nucleated. Finely vacuolated eosinophilic cytoplasms

Answer 1

Atrial myoxoma

Question 2

Atrial myoxoma (benign/malignant)

Answer 2

benign (though can metastasize)

Question 3

Most common primary pediatric tumor of the heart

Answer 3

Cardiac rhabdomyoma

Question 4

Neoplasm with the greatest propensity to metastasize to the heart

Answer 4

Melanoma

Question 5

Areas of mycardium with brown/black pigment

Answer 5

Metastasizing melanoma

Question 6

tumors are of neural origin and arise from Schwann cells.

Answer 6

Granular cell tumor

Question 7

Most common GI site for granular cell tumor

Answer 7

esophagus

Question 8

two main forms of esophageal cancer

Answer 8

squamous cell carcinoma and adenocarcinoma

Question 9

Esophageal … are similar to head and neck cancer in their appearance and association with tobacco and alcohol consumption.

Answer 9

squamous cell carcinoma

Question 10

Esophageal …. are most often associated with a history of gastroesophageal reflux disease and Barrett’s esophagus

Answer 10

adenocarcinomas

Question 11

….. cancer accounts for ~ 90 - 95% of all esophageal cancer worldwide, however in the U.S. ~ 50 - 80% of all esophageal cancer cases are …..

Answer 11

squamous cell / adenocarcinoma

Question 12

Most common benign tumor of the esophagus

Answer 12

leiomyoma

Question 13

one commonly finds gastricmucosa withinfiltration by neutrophils.

Answer 13

acute gastritis

Question 14

Small curved to spiral rod-shaped bacterium is found in the surface epithelial mucus are seen here with a methylene blue stain.

Answer 14

H. pylori

Question 15

… ulcers typically have smooth, regular, rounded edges with a flat, smooth base and radiating mucosal folds.

Answer 15

Benign

Question 16

… ulcers typically have irregular, heaped or overhanging margins often with an nodular and irregular mass that may be ulcerated which protrudes into the lumen of the stomach

Answer 16

malignant

Question 17

triad of gastric acid hypersecretion, severe peptic ulceration, and non-beta cell islet tumor of pancreas (gastrinoma).

Answer 17

Zollinger-Ellison

Question 18

In most cases of Zollinger-Ellison syndrome, a … is found in either the pancreas or in the duodenum.

Answer 18

gastrinoma

Question 19

The neoplastic glands of demonstrate mitoses, increased nuclear/cytoplasmic ratios and hyperchromatism

Answer 19

gastric adenocarcinoma

Question 20

rows of infiltrating neoplastic cells with marked pleomorphism are seen. Many of the neoplastic cells have clear vacuoles of mucin.

Answer 20

gastric adenocarcinoma

Question 21

are a class of neuro-endocrine neoplasms that arise from enterochromaffin cells.

Answer 21

carcinoid tumors

Question 22

Over two-thirds of are found in the gastrointestinal tract.

Answer 22

carcinoid tumors

Question 23

Increased risk for intestinal adenocarcinoma

Answer 23

ulcerative colitis

Question 24

Most common benign small bowel tumors

Answer 24

Hyperplastic polyps, adenomas, leiomyomas, lipomas, hamartomas

Question 25

elongated spindle cells containing cigar-shaped nuclei and no evidence of increased mitotic activity is seen.

Answer 25

leiomyoma

Question 26

the most common type of small bowel malignancy in the US.

Answer 26

adenocarcinoma

Question 27

Other malignancies of the small bowel include

Answer 27

carcinoid tumors, lymphomas or sarcoma aka gastrointestinal stromal tumors (GISTs).

Question 28

have a typical endocrine appearance with collections of small round cells containing nuclei that are consistent in size and shape and surrounded by cytoplasm which stains pink to pale blue

Answer 28

nests of carcinoid tumor

Question 29

There is still a glandular configuration but the glands are irregular and very crowded. Many of them have lumens containing bluish mucin.

Answer 29

Adenocarcinoma of the colon

Question 30

At higher magnification, the neoplastic glands of adenocarcinoma have crowded nuclei with hyperchromatism and pleomorphism. No normal goblet cells are seen in this specimen.

Answer 30

Adenocarcinoma of the colon