GI Flashcards

0
Q

characterized by increased tone and pressure at the lower esophageal sphincter (LES), diminished to absent peristalsis in the distal portion of the esophagus and lack of a coordinated LES relaxation in response to swallowing.

A

Achalasia

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1
Q

4 esophageal motility disorders

A

Achalasia, diffuse esophageal spasm, nutcracker esophagus and hypertensive lower esophageal spasm

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2
Q

lymphocytic infiltration of Auerbach’s plexus and destruction of ganglion cells is likely the underlying pathophysiology that results in this condition.

A

Achalasia

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3
Q

contractions are uncoordinated and several segments of the esophagus contract simultaneously

A

Diffuse esophageal spasm

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4
Q

contractions proceed in a coordinated manner but the amplitude is excessive.

A

Nutcracker esophagus

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5
Q

bleeding from tears in the mucosa at the junction of the stomach and esophagus

A

Mallory-Weiss syndrome

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6
Q

The tear involves mucosa and submucosa but not the muscular layer.
Usually caused by severe coughing, retching or vomiting.

A

Mallory-Weiss tear

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7
Q

full thickness tear or rupture of the esophageal wall that can occur as a consequence of severe retching or vomiting.

A

Boerhaave’s Syndrome

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8
Q

condition characterized by mucosal damage to the esophageal lining due to stomach acid reaching the esophagus.

A

GERD

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9
Q

autoimmune disorder of the small intestine caused by a reaction to gliadin, a gluten protein found in wheat and other common grains such as barley and rye.

A

Celiac dz

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10
Q

leads to villous atrophy (shortening of the villi lining the small intestine).

A

celiac dz

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11
Q

can affect any part of the gastrointestinal tract from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum.

A

Crohn’s

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12
Q

is restricted to the colon and the rectum.

A

ulcerative colitis

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13
Q

Microscopically, … is restricted to the mucosa while …. affects the whole bowel wall (“transmural lesions”).

A

ulcerative colitis / crohn’s

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14
Q

Most common cause of viral enteritis

A

Norwalk virus

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15
Q

Most common cause of severe diarrhea in infants and young children

16
Q

picnic food poisoning

A

staph aureus

17
Q

chinese restaurant food poisoning

18
Q

food poisoning from salt water crabs and shrimp

19
Q

canned fruits and veggies food poisoning

20
Q

an autosomal dominant disorder characterized by mucocutaneous pigmentation (i.e. lesions on the face, lips, and buccal mucosa) and benign GI hamartomas.

A

Peutz-Jeghers syndrome

21
Q

Histologically, the lesions seen in …. feature a distinctive frond-like appearance with a stromal/smooth muscle core that is covered by acinar glands and normal mucosa. Nuclear atypia is absent.

A

puetz-jeghers

22
Q

(benign/pre-malignant/malignant) hyperplastic polyp

23
Q

(benign/pre-malignant/malignant) tubular adenoma

A

pre-malignant

24
(benign/pre-malignant/malignant) colorectal adenocarcinoma
malignant
25
Most common type of poyp in the colon
hyperplastic
26
glands that are more irregular and contain darker and more crowded nuclei. This neoplasm is benign and well-differentiated, as it still closely resembles the normal colonic structure.
adenomatous polyp
27
polyp that is stalk-like
adenomatous polyp
28
sessile polyp
villouos adenoma
29
tubular adenoma
adenomatous polyp
30
characterized by the appearance of multiple polyps in the gastrointestinal tract, usually in a child, adolescent or young adult.
Juvenile polyposis syndrome
31
While the majority of the polyps found in ... are non-neoplastic, hamartomatous, self-limiting and benign, there is an increased risk of developing adenocarcinoma.
Juvenile Polyposis Syndrome
32
an inherited condition in which hundreds to thousands of polyps form mainly in the epithelium of the large intestine.
Familial adenomatous polyposis
33
While these polyps start out benign, malignant transformation into colon cancer occurs when not treated
Familial adenomatous polyposis
34
The combination of polyposis, osteomas, fibromas and sebaceous cysts is termed
Gardner's Syndrome