Final Exam Flashcards

(224 cards)

1
Q

3 pacemakers of the heart

A

SA node (60-100)
AV node (40-60)
purkinje fibers (20-40)

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2
Q

afib S&S

A

dizziness, palpitations, syncope, dyspnea, fatigue

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3
Q

management for afib

A

Manage obesity, HTN, obstructive sleep apnea, diabetes, smoking, alcohol, caffeine, surgery

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4
Q

meds for afib

A

anticoags (watch plt count)
BB (better than digitalis, not for pts in HF or hx bronchospasm)
Ca+ channel blockers (verapamil/diltiazem, good for pts w asthma, COPD, HTN, and HF)
digitalis (w BB)
amiodarone (converts rate and rhythm, ibutilide)
rhythm control for symptoms

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5
Q

procedures for afib

A

radiofrequency ablation
maze with cryoablation
Transesophageal echocardiogram for atrial thrombus
cardioversion (not for pts with clot)
catheter ablation

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6
Q

electrical cardioversion things to know

A

patient is NPO for 6 hours pre-procedure, IV access needed, anterior and posterior pads placed patient sedated with IV midazolam & propofol. Synchronized electrical shocks delivered. Observe for burns, alleviate discomfort

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7
Q

pharmacologic cardioversion

A

Using antiarrhythmics (amiodarone, sotalol, flecainide) for patient who developed afib within the past 7 days. Monitor HR, BP, K+, perform EKG to assess for QT prolongation. Contraindicated in digitalis toxicity, multifocal atrial tachycardia and sub-optimal anticoagulation

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8
Q

what anticoag to use in patients with mechanical heart valves

A

warfarin!! But watch vitamin K and do frequent INR draws

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9
Q

procedure for pts who can’t handle long term anticoags

A

left atrial appendage obliteration for stroke prevention as this is the main site for thrombus formation

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10
Q

target INR

A

2-3

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11
Q

complications of afib

A

clots causing CVA, MI, or cognitive decline (from micro emboli)
hypoperfusion from < CO (heart failure)

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12
Q

findings of angina

A

May be described as tightness, choking, or a heavy sensation
Frequently retrosternal (behind sternum, deep pain) and may radiate to neck, jaw, shoulders, back or arms (usually left)
Anxiety frequently accompanies the pain
Other symptoms may occur: dyspnea or shortness of breath, dizziness, nausea, and vomiting

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13
Q

unstable angina

A

characterized by increased frequency and severity and is not relieved by rest and NTG.
No longer managed with NTG, pain still exists

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14
Q

priorities for treating angina

A

no activity (semi-fowler)
VS, resp distress, pain
ECG
meds (NTG)
2L oxygen

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15
Q

pt teaching for angina

A

avoid extreme temps
avoid OTC meds that > HR or BP
no nic or fat
high fiber
maintain normal BP and glucose

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16
Q

NTG bottle

A

dark, keep away from kids and sunlight

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17
Q

unstable angina vs STEMI vs NSTEMI

A

Unstable angina, coronary ischemia but no acute MI
STEMI: acute MI, damage to myocardium
NSTEMI: elevated biomarkers, no ECG evidence of MI, less damage

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18
Q

manifestations of MI

A

Chest pain: Occurs suddenly and continues despite rest and medication
SOB; C/O indigestion; nausea; anxiety; cool, pale skin; increased HR, RR
ECG changes: Elevation in the ST segment in two contiguous leads is a key diagnostic indicator for MI
Lab studies: cardiac enzymes, troponin, creatine kinase (muscle damage), myoglobin

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19
Q

MONA and VOMIT

A

morphine, oxygen, nitrates, aspirin
vitals, oxygen, monitor, IV, time (if few hrs, give clot busters)

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20
Q

S&S of MI in women

A

Sweating: Similar to stress sweat, rather than sweating from exercise
SOB: Typically trouble breathing for no reason
Fatigue: Extreme tiredness
Chest pain or discomfort: The pain can be anywhere in the chest, not just the left side
Pain in the arms, back, neck, or jaw
Pain can be gradual or sudden
Nausea
Flu-like symptoms, including nausea, may occur a few days before a heart attack
Stomach pain: Can range in intensity from heartburn-like pain to severe abdominal pressure

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21
Q

emergency procedure for MI

A

CABG

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22
Q

hypertrophic and dilated heart

A

cardiomyopathy

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23
Q

right sided HF

A

Viscera (near abdominal area, ASCITES) and peripheral congestion
JVD
Dependent edema
Hepatomegaly
Ascites
Weight gain

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24
Q

Left sided HF

A

Pulmonary congestion, crackles
S3 or ventricular gallop (happens with HTN, right after S2, S4 is right before S1)
Dyspnea on exertion (DOE)
Activity level before you feel out of breath
Diet
How many pillows
Low O2 sat
Dry, nonproductive cough initially
Ace inhibitors, arbs taken instead
Oliguria

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25
systolic HF
blood can't pump Impaired contractile function (like scar tissue from MI) Increased afterload Cardiomyopathy (hypertrophic & dilated) Mechanical abnormalities (valve disease) Decreased left ventricular ejection fraction (EF)
26
when to get heart transplant
EF: 5-10%
27
diastolic HF
Impaired ability of the ventricles to relax and fill during diastole, resulting in decreased stroke volume and CO Heart failure with normal (preserved) EF Problem filling, not getting blood out Result of left ventricular hypertrophy from hypertension, MI, valve disease, or cardiomyopathy
28
mixed HF
Seen in disease states such as dilated cardiomyopathy (DCM) Poor EFs (<35%) High pulmonary pressures Biventricular failure Both ventricles may be dilated and have poor filling and emptying capacity
29
compensatory mechanism for HF
adrenal glands
30
catecholamines
nor and epi
31
compensatory mechanisms for HF
SNS neurohormonal responses ventricular remodeling dilation hypertrophy
32
SNS in HF
released epi and norepi increased HR, contractility, peripheral vasoconstriction helps then harms
33
neurohormonal responses in HF
kidneys release renin and initiate RAAS ADH secretion endothelin released proinflammatory cytokines (CRP and homocysteine, seen in MI and HF)
34
what lab value indicates HF
BMP
35
ventricular remodeling
Results from SNS activation and neurohormonal responses Hypertrophy of ventricular myocytes Ventricles larger but less effective in pumping Can cause life-threatening dysrhythmias and sudden cardiac death Might get implantable defibrillator in case this happens
36
dilation in HF
enlargement of chambers initially effective then CO decreases
37
hypertrophy in HF
increased cardiac wall thickness effective at first then leads to poor contractility, increased O2 needs, poor circulation, and v-dysrhythmias
38
FACES in chronic HF
fatigue activity intolerance chest congestion/cough edema SOB
39
Paroxysmal nocturnal dyspnea
SOB that wakes the pt up
40
anasarca
entire body has pitting edema, fluid comes from pores, soaking bed, end stage very uncomfy, give morphine
41
weight gain in ADHF
>3lbs in 2 days
42
meds for HF
ACE inhibitors (vasodilation, diuresis, watch for hypotension, hyperkalemia, bad renal, cough) angiotensin II (alternative to ace) Hydralazine and isosorbide dinitrate (alternative to ace) BB (careful w asthma) diuretics (watch electrolytes) digitalis (watch for toxicity esp with hypokalemia) IV milrinone (hypotension) and dobutamine
43
gerontologic considerations for HF
May present with atypical signs and symptoms such as fatigue, weakness, and somnolence Decreased renal function can make older patients resistant to diuretics and more sensitive to changes in volume Administration of diuretics to older men requires nursing surveillance for bladder distention caused by urethral obstruction from an enlarged prostate gland
44
activity for HF patient
30-45 mins daily 2 hrs after eating avoid extreme temps
45
manifestations of pulmonary edema
restlessness, anxiety, dyspnea, cool and clammy skin, cyanosis, weak and rapid pulse, cough, lung congestion (moist, noisy respirations), increased sputum production (sputum may be frothy and blood tinged), decreased LOC
46
meds for cardiogenic shock
diuretics positive inotrope (+ contractility) vasopressors
47
circulatory assist devices
intra-aortic balloon pump (temporary, does work for the heart)
48
mani of cardiac tamponade
ill-defined chest pain or fullness, pulsus paradoxus, engorged neck veins, labile or low BP, shortness of breath Cardinal signs of cardiac tamponade: falling systolic BP, narrowing pulse pressure, rising venous pressure, distant heart sounds
49
treatments for cardiac tamponade
Pericardiocentesis: Puncture of the pericardial sac to aspirate pericardial fluid Pericardiotomy: Under general anesthesia, a portion of the pericardium is excised to permit the exudative pericardial fluid to drain into the lymphatic system
50
endocarditis
from unresolved strep-A incompetent valves
51
treatment for endocarditis
spironolactone (can cause gynecomastia/big boobs) use eplerenone instead empagliflozin
52
Classes I-IV of HF
I: No limitation II: Slight limitation, rest is good but lots of activity causes fatigue III: Less activity causes fatigue but rest is good IV: Fatigue even at rest
53
manifestations of ischemic stroke
Symptoms depend on the location and size of the affected area Numbness or weakness of face, arm, or leg, especially on one side Confusion or change in mental status Trouble speaking or understanding speech Difficulty in walking, dizziness, or loss of balance or coordination Sudden, severe headache Perceptual disturbances
54
hemiplegia
one side paralysis
55
hemiparesis
one side weakness
56
hemianopsia
only seeing on one side
57
agnosia
not recognizing objects
58
care of patient after stroke
primarily supportive Bed rest with sedation Oxygen Treatment of vasospasm, increased ICP, hypertension, potential seizures, and prevention of further bleeding Deliberate CALM care!! watch for fever and high bp (ischemic stroke and > ICP) check glucose (high is bad) don't give dextrose HOB 30
59
mani of hemorrhagic stroke
Similar to ischemic stroke Severe headache Early and sudden changes in LOC Vomiting Bleeding
60
assessment during acute phase of stroke
LOC and neuro assessment GCS pupil I&Os BP bleeding O2
61
nursing care after acute phase of stroke
Mental status Sensation/perception Motor control Swallowing ability Nutritional and hydration status Skin integrity Activity tolerance Bowel and bladder function Get men ready to pee again once they’re stable enough to stand
62
how often to turn patient after stroke
q2h prom or arom 4-5x/day
63
diet for post CVA
Chin tuck or swallowing method Use of thickened liquids or pureed diet Ice chips bad!!
64
how often to do neuro assessment post CVA
q2-4h
65
aneurysm precautions
Absolute bed rest with HOB 30 degrees Avoid all activity that may increase ICP or BP; Valsalva maneuver, acute flexion or rotation of neck or head Stool softener and mild laxatives so they don’t bear down Non-stimulating, non-stressful environment; dim lighting, no reading, no TV, no radio Visitors are restricted
66
early identification of aneurysm rupture
Call RRT (neuro) Initiating stroke algorithm Ensure labs are sent prior to CT scan CBC, BMP, coags, T&S
67
nursing interventions to maintain airway
HOB >30 suction and O2 assessment
68
modified massey bedside swallow test
complete with time and date (cva and tia) within 24h of new tia/cva can't just document +/- gag when in doubt, NPO
69
right sided stroke
Left paralysis Spatial difficulties Impulsive behavior Poor judgment Time blindness
70
left stroke
Right paralysis difficulty knowing left and right slow cautious movements impaired cognition dep and anxiety
71
decorticate
Plantar flexed (feet point OUTWARD) Legs internally rotated Arms flexed and adducted (towards midline) Hands flexed BETTER PROGNOSIS
72
decerebrate
Plantar flexed (feet point OUTWARD) Arms adducted (toward midline), extended, pronated, and hands flexed outward
73
GCS-eye
4 Spontaneous 3 Loud voice 2 Pain 1 None
74
GCS-verbal
5 Normal conversation 4 Disoriented conversation 3 Non coherent 2 No words, only sounds 1 None
75
GCS-motor
6. Normal 5. Localized to pain 4. Withdraws to pain 3. Flexion 2. Extension 1. None
76
CN1 and test
olfactory smell stuff
77
CN2 and test
optic snellen wiggle fingers and move hand medially, ask when pt sees it ishihara for color blindness pt looks at you while you wiggle fingers in each quadrant pupil reflex fundoscope
78
CN3 and test
oculomotor 6 cardinal points in H PERRLA
79
CN4 and test
trochlear 6 cardinal points in H PERRLA
80
CN5 and test
trigeminal dull sharp corneal reflex with cotton, pt should blink resist jaw against hand jaw jerk should cause protrusion
81
CN6 and test
abducens 6 cardinal points in H PERRLA
82
CN7 and test
facial raise eyebrows close eyes tight puff cheeks and show teeth taste
83
CN8 and test
vestibulocochlear/acoustic rinne (forehead > ear) weber (ear=ear)
84
CN9 and test
glossopharyngeal swallow/gag reflex phonation taste
85
CN10 and test
vagus swallow/gag reflex phonation taste
86
CN11 and test
spinal accessory shrug against resistance
87
CN12 and test
hypoglossal stick out tongue, is it straight
88
obtunded
Difficult to arouse, needs constant stimulation to follow a simple command
89
stupor
Arouses to vigorous, continuous stimulation (can’t follow a simple command) severe impairment to brain circulation may become comatose
90
akinetic mutism
unresponsiveness, no movement or sound, sometimes opens eyes
91
PVS
sleep-wake! no cognitive function
92
locked in syndrome
Inability to move or respond except for eye movements due to a lesion affecting the pons (according to Chicago Med, some pts can move eyes up and down but not side to side)
93
cushing's triad
Increased SBP w widening pulse pressure Bradycardia Bradypnea seen in herniation syndrome
94
normal ICP
1-15
95
early mani of increased ICP
Changes in LOC Any change in condition Restlessness, confusion, increased drowsiness, increased respiratory effort, purposeless movements (loss of spontaneous movement), hemianopsia, lost taste for sweet and salty, pulse and pulse pressure changes Pupillary changes and impaired ocular movements Weakness in one extremity or one side Headache: constant, increasing in intensity, or aggravated by movement or straining
96
late mani of increased ICP
Respiratory and vasomotor changes VS: major changes Cushing triad: bradycardia/pnea, HTN Projectile vomiting Further deterioration of LOC Going from stupor to coma Hemiplegia, decortication, decerebration, or flaccidity Respiratory pattern alterations including cheyne-stokes breathing and arrest Loss of brainstem reflexes: pupil, gag, corneal, and swallowing
97
brain tumor mani
depends on location and size Localized or generalized neurologic symptoms Symptoms of increased ICP Headache Vomiting Visual disturbances Seizures hormonal if pituitary loss of hearing, tinnitus, and vertigo if acoustic
98
planning for radical neck dissection
absence of infection viability of graft nutrition and fluids
99
laryngeal cancer early S&S
Hoarseness (lower voice) of more than 2 weeks’ duration occurs ACE inhibitors (-prils) cause cough and polyps in throat (not cancer but check! Persistent cough or sore throat and pain and burning in the throat A lump may be felt in the neck.
100
later symptoms of laryngeal cancer
Dysphagia Dyspnea Unilateral nasal obstruction or discharge Persistent hoarseness Persistent ulceration and foul breath (late symptoms) Cervical lymphadenopathy Unintentional weight loss General debilitated state Pain radiating to the ear may occur with metastasis
101
S&S of resp alkalosis
lightheadedness, inability to concentrate, numbness and tingling, sometimes loss of consciousness
102
S&S of resp acidosis
may be asymptomatic Symptoms may be suddenly increased pulse, respiratory rate and BP, mental changes, feeling of fullness in head
103
what type of pressure do we want in lungs
negative!
104
internal beam radiation
implant that is right next to tumor, less systemic side effects
105
brachytherapy
seeds, don’t be near pregnant women and be cautious with immune system threat
106
external radiation
Can be scary bc mimics pulmonary cancer S&S fatigue bc of bone marrow suppression
107
risk factors for breast ca
longer exposure to estrogen obesity high fat diet alc fibrositis (dense tissue)
108
breast cancer screening
20-30s, breast exam q3y annual after age 40 annual mammo at 40
109
fine needle aspiration biopsy for breast cancer
fluid=cyst=benign
110
hormonal therapy for breast ca
Estrogen and progesterone receptor assay (Moms genetic coding is checked and meds are given for specific type of cancer) SERMs (tamoxifen/causes uterine) aromatase inhibitors (anastrozole, letrozole, exemestane)
111
physical therapy after mastectomy
exercise 3x/day for 20 mins do not lift over 5-10 lbs
112
when to remove drains after mastectomy
<30ml drainage in 24 hrs for 2 days usually 7-10 days
113
palliative surgery
DEBULKING radiation, chemo, pain control
114
specific gravity
1.010-1.025
115
serum creatinine
0.6-1.2
116
BUN
7-18 8-20 for >60
117
3 way bladder irrigation
Urine should be a little pinkish first day, should NOT look cranberry color. If clots are there, they should be small enough to pass Irrigating bladder wall, VERY vascular so minimize bleeding
118
mani of cirrhosis
Jaundice is late manifestation Portal hypertension, ascites, and varices (a varicose vein, outpouching of the vein, can rupture) Hepatic encephalopathy or coma Nutritional deficiencies
119
hepatocellular jaundice
May appear mildly or severely ill Lack of appetite, nausea, weight loss Malaise, fatigue, weakness Headache chills and fever if infectious in origin (like hepatitis)
120
obstructive jaundice
Dark orange-brown urine and light clay-colored stools Dyspepsia and intolerance of fats, impaired digestion Pruritus (can also be a sign of hodgkin’s lymphoma)
121
treatment of ascites
Low-sodium diet Diuretics (often a combination of diff classes) Bed rest Paracentesis Administration of salt-poor albumin Transjugular intrahepatic portosystemic shunt (TIPS) to continually remove fluid
122
hepatic encephalopathy
A life-threatening complication of liver disease. May result from the accumulation of ammonia and other toxic metabolites in the blood
123
assessments with hepatic encephalopathy
LOC q15-30 minutes seizures fetor hepaticus (shit breath) f&e and ammonia asterixis
124
medical management of hepatic encephalopathy
Lactulose to reduce serum ammonia levels IV glucose to minimize protein catabolism Protein restriction Reduction of ammonia from GI tract by gastric suction, enemas, oral antibiotics (not eating, they have an NG tube, meds go IV, not NG) Discontinue sedatives analgesics and tranquilizers Monitor for and promptly treat complications and infections
125
portal HTN
Obstructed blood flow through the liver results in increased pressure throughout the portal venous system (everything is backing up, like a reflux)
126
results of portal HTN
Ascites (abdominal fluid buildup, usually peritoneal, puts pressure on diaphragm which causes SOB) Esophageal varices (when these rupture, pt vomits bright red BADDD smelling blood)
127
pancreatic (pancreatitis) cancer treatment
Use of analgesics Nasogastric suction to relieve nausea and distention Frequent oral care Bed rest Measures to promote comfort and relieve anxiety
128
common bile duct obstruction complications
chronic pancreatitis type 1 diabetes Fluid and electrolyte disturbances Necrosis of the pancreas Shock Multiple organ dysfunction syndrome DIC jaundice pruritus RUQ pain anorexia fever, fatigue If left untreated, infections, sepsis, and liver disease
129
complications of pancreatitis
Fluid and electrolyte disturbances Necrosis of the pancreas Shock Multiple organ dysfunction syndrome DIC
130
SIADH fluid restriction
<800ml/day
131
S&S of SIADH
Weight gain without edema, weakness, anorexia, N/V, personality changes, seizures, oliguria, decreased reflexes, coma, hyponatremia
132
treatment of SIADH
Treat underlying malignancy & correct the sodium- water imbalance (fluid restriction, oral salt tablets or isotonic [0.9]) saline and IV administration of 3% sodium chloride solution. Furosemide (Lasix) may also be a helpful treatment in the initial phases. Demeclocycline (Declomycin) may be needed on an ongoing basis Monitor sodium level
133
diabetes insipidus
decreased ADH Excessive urine output Decreased urine osmolality Serum hyperosmolality Give IV fluids, electrolyte replacement and desmopressin (synthetic vasopressin) Hypopituitary
134
addison's disease
adrenocortical insufficiency adrenal suppression
135
addison's disease S&S
Muscle weakness, anorexia, GI symptoms, fatigue, dark pigmentation of skin and mucosa, hypotension, low blood glucose, low serum sodium, high serum potassium, apathy, emotional lability, confusion
136
diagnostic tests for addison's
adrenocortical hormone levels, ACTH levels, ACTH stimulation test low sodium, high potassium bronze skin
137
assessments for addison's
Note any illness or stressors that may precipitate problems Fluid and electrolyte status VS and orthostatic blood pressures Note signs and symptoms related to adrenocortical insufficiency: weight changes, muscle weakness, fatigue
138
interventions for addison's
monitor for signs and symptoms of fluid volume deficit; encourage fluids and foods; select foods high in sodium; administer hormone replacement as prescribed Activity intolerance; avoid stress and activity until stable, perform all activities for patient when in crisis; maintain a quiet, non stressful environment; measures to reduce anxiety
139
cushings
Excessive adrenocortical activity or corticosteroid medications
140
mani of cushings
Hyperglycemia; central-type obesity with “buffalo hump;” heavy trunk and thin extremities; fragile, thin skin; ecchymosis; striae; weakness; lassitude; sleep disturbances; osteoporosis; muscle wasting; hypertension; “moon-face”; acne; infection; slow healing; virilization in women; loss of libido; mood changes; increased serum sodium; decreased serum potassium
141
**tests for cushing's
ACTH stimulation test and dexamethasone suppression
142
assessment for cushings
Activity level and ability to carry out self-care Skin assessment Changes in physical appearance and patient responses to these changes Mental function Emotional status Medications
143
addisonian crisis
complication of addison's too much too little Profound fatigue Dehydration Vascular collapse (low BP) Renal shutdown Decreased sodium, increased potassium
144
planning for cushings
decreased risk of injury, decreased risk of infection, increased ability to carry out self-care activities, improved skin integrity, improved body image, improved mental function, and absence of complications
145
corticosteroid therapy
Suppress inflammation and autoimmune response, control allergic reactions, and reduce transplant rejection long half life, same time per day TAPER! blister pack to taper immunosuppression increased glucose personality in kids
146
SNS
Pupils dilate Bronchodilation Increased HR Smaller blood vessels constrict Relaxed GI Relaxed bladder and uterus
147
PNS
Constricted pupils Constricted bronchioles and increased secretions Decreased HR Dilated blood vessels Increased peristalsis and secretions Contracted bladder Increased salivation
148
treatment for hyperthyroidism
treatment of choice is removal modified or radical neck dissection, possible radioactive iodine to minimize mets seeds to shrink tumor before surgery
149
caffeine and thyroid
avoid caffeine thyroid storm!
150
preop education for thyroid surgery
dietary guidance no caffeine and stimulants explain tests and procedures head + neck support look for shoulder drop to make sure we didn't cut into sternocleidomastoid muscle
151
postop management for thyroid surgery
Monitor respirations; potential airway impairment Monitor for potential bleeding and hematoma formation; check posterior dressing Assess pain and provide pain relief measures Semi-Fowler position, support head and neck Assess voice, discourage talking Potential hypocalcemia related to injury or removal of parathyroid glands
152
parathormone regulates what 2 electrolytes and how
calcium and phosphorus increases serum Ca and decreases ph
153
hyperparathyroidism
may have no symptoms apathy, fatigue, muscle weakness, nausea, vomiting, constipation, hypertension, and cardiac dysrhythmias may occur mimics depression
154
hypercalcemic crisis**
neuro, cardio, and renal symptoms life threatening rapid isotonic rehydration calcitonin and corticosteroids given
155
3 causes of hypoparathyroid
Abnormal parathyroid development Destruction of the parathyroid glands (surgical removal or autoimmune response) Vitamin D deficiency
156
clinical mani of hypoparathyroid
Tetany, numbness, tingling in extremities, stiffness of hands and feet, bronchospasm, laryngeal spasm, carpopedal spasm, anxiety, irritability, depression, delirium, ECG changes Carpopedal spasm = chvostek trousseau
157
chvostek and trousseau
chvostek: sharp tap in front of parotid and ear, spasm of mouth, nose, and eye trousseau: BP cuff for 3 mins, gay italian hand
158
management of hypoparathyroid
increase calcium to 9-10 calcium gluconate pentobarbital to decrease muscular irritability parathormone low stim environment high calcium, low phosphorus vit d
159
medical management of pituitary tumors
Stereotactic radiation (external beam) bromocriptine/octreotide (inhibits GH and octreotide shrinks tumor)
160
surgical management of pituitary tumor
Hypophysectomy (removal of pituitary gland, also for cushing’s and palliation for bone pain) Irradiation Cryosurgery Menstruation stops Infertility after total or near-total ablation of pituitary Replacement therapy with corticosteroids and thyroid hormone
161
adrenal crisis S&S
low cortisol dizziness, weakness, sweating, abd pain, N/V, LOC, rapid weak pulse, rapid RR, pallor
162
CLL
Malignant clone of B lymphocyte (T lymphocyte CLL is rare) *Most of leukemic cells of CLL are mature, (may have escaped/resisted apoptosis) men > 60 2-14 year survival
163
diagnosis and mani of CLL
Normal or ↓erythrocytes and platelet Early: ↑lymphocyte count Lymphadenopathy- Swollen painful nodes; Enlarged liver and spleen Later stage: Thrombocytopenia Auto-immune complications can occur at any stage. B symptoms: Night sweats, unintentional wt loss; infections
164
medical management of CLL
early: no treatment, monitor late: begin! chemo, monoclonal antibody therapy, IVIG, HSCT
165
hodgkin's lab findings
Reed Sternberg cell or be of viral etiology. Mediastinal mass on X-ray Assess for B symptoms PET scan; CT of chest, abd and/or pelvis Lab: EST, Liver & Renal studies Unilateral, painless enlargement of lymph node on neck
166
hodgkin's S&S
related to compression of organs involved ie: Compression of trachea cough; pleural effusion; abdominal pain; Pruritus; Herpes Zoster Severe pain on ingestion of alcohol; anemia; B symptoms; normal or slightly decreased platelet count; decrease skin sensitivity test
167
lab findings of tumor lysis
HYPERuricemia HYPERphosphatemia HYPERkalemia HYPOcalcemia
168
S&S of tumor lysis
N/D, muscle cramps, confusion, weakness, seizures
169
resp mani at EOL
cheyne stokes accessory muscles irregular and slowing down can't cough or clear secretions death rattle is fluid from lungs building up
170
hearing and touch mani at EOL
hearing is the last sense to go decreased sensation to hot and cold decreased perception of pain and touch
171
taste, smell, and sight mani at EOL
blurred vision no blinking eyelids half open decreased taste and smell
172
skin mani at EOL
mottling cold, clammy cyanosis of nose, nails, knees wax like skin when close to death (looks wet)
173
urinary mani at EOL
decrease in output incontinent unable to urinate
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GI mani at EOL
slow GI tract and possible cessation accumulation of gas distension and nausea incontinent BM before or at time of death
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musculoskeletal mani at EOL
loss of ability to move trouble holding body posture and alignment loss of facial muscle tone (sagging jaw, difficulty speaking, no gag reflex, go from normal to puree to NPO)
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cardio mani at EOL
tachy then slow, weak pulse irregular decreased BP delayed absorption of IM or SQ
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HIV
Targets CD4+ lymphocytes AKA T-cells T-cells and B-cells work together HIV integrates its RNA into host cell DNA through reverse transcriptase, reshaping the host's immune system
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3 infection stages of HIV
stage 1: CD4+ 500 Stage 2: CD4+ 200-499 Stage 3 (AIDS): CD4+ <200, T-lymphocytes >14%
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B-cell lymphoma
non-hodgkins
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non-hodgkin's lymphoma
b-lymphocyte average age 50-60
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diagnosis of non-hodgkins
CT PET Bone marrow biopsy CNS fluid analysis
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S&S of non-hodgkins
multiple lymph nodes! B symptoms (33%) Less aggressive forms can wax and wane Asymptomatic in early stage. Lymphadenopathy in stage 3-4. Lymph masses can compromise organ functions e.g. respiratory, spleen CNS; urinary
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treatment for non-hodgkins
Bone marrow transplant & stem cell transplant may be considered for younger patients. Chemo Radiation: If the disease is not aggressive radiation alone may be needed. Lifetime screening
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kaposi sarcoma
Oncologic manifestation of HIV a malignancy of endothelial cells that line the blood vessels chronic, benign
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kaposi sarcoma mani
dark reddish-purple lesions of the skin, oral cavity, gi tract, and lungs
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kaposi sarcoma risk factors
older men mediterranean or jewish endemic (african) ks: eastern half of africa, men, resembles classic iatrogenic/organ transplant-associated ks: organ transplant patients and immunosuppressants occurs with AIDS, aggressive
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AIDS defining illnesses
HIV encephalopathy, pneumocystis, recurrent PNA
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complications of AIDS
Opportunistic (secondary) infections Most common are fungal Impaired breathing or respiratory failure Wasting syndrome and f&e imbalance Electrolyte imbalance kills most ppl, same w chemo Adverse effects of medications
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4 causes of blindness
macular degeneration glaucoma cataracts diabetic retinopathy
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glaucoma
Disturbance of the functional or structural integrity of the optic nerve. This is characterized by increased fluid secretion or decreased fluid drainage which increases intraocular pressure and can cause atrophy of the optic nerve and deterioration of vision
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open angle glaucoma
more common aqueous humor secretion decreased bc of blockage in schlemm increased pressure in eye
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S&S of open angle glaucoma
headache mild pain loss of peripheral vision halos around lights IOP 22-23
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treatment of open angle glaucoma
cholinergics (carbachol, echothiophate, pilocarpine) adrenergic agonists (Apraclonidine, brimonidine tartrate, dipivefrin) BB Carbonic anhydrase inhibitors (-lamide) prostaglandin analogs (-prost)
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surgery for open angle glaucoma
Laser trabeculectomy Iridotomy Placement of shunts to allow fluid to circulate better
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closed angle glaucoma
There is a closure of the angle of the iris and the sclera which causes a sudden and dramatic rise in intraocular pressure This is an emergent situation
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S&S of closed angle glaucoma
Severe pain Blurred vision, decreased vision, loss of vision Pupils that do not respond to light Light sensitivity Halos around lights are seen IOP greater than 30 mm Hg
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treatment of closed angle glaucoma
osmotics (mannitol or glycerin) cholinergics adrenergic agonist BB carbonic anhydrase inhibitors (-lamide) prostaglandin analogs (-prost)
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surgery for closed angle glaucoma
Laser trabeculectomy Iridotomy Placement of shunts to allow fluid to circulate better same as open angle
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administering eye drops
antiseptic technique sit upright or lay down with chin up -dropper held 1-2cm above conjunctival sac -don't drop onto cornea -gentle pressure on tear duct to prevent systemic absorption -wait 5 min if multiple -ointments should go inner to outer corner
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administering ear drops
aseptic technique room temp sit upright or lie on side straighten ear canal by pulling UP AND OUT for adults and BACK for children <3 dropper 1cm above canal apply gentle pressure to tragus unless too painful no cotton inside ear, just outermost part of canal stay in side-lying for 2-3 mins
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meniere's disease
A chronic disorder of the inner ear involving sensorineural hearing loss, severe vertigo and tinnitus
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meniere's and aspirin
no aspirin
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meds for meniere's
antihistamines tranquilizers antiemetic diuretic gentamycin
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2 surgeries for meniere's
Endolymphatic sac decompression: shunting. Basically a drain, first-line, safe, effective, and quick Vestibular nerve sectioning: preserves hearing if done that way. Cutting the nerves stops auditory input brief stay
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basal cell carcinoma
appears on sun exposed hands,face, neck, scalp small waxy nodule may appear shiny, flat, gray, yellow rarely metastasizes reoccurrence common
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surgery of basal cell carcinoma
surgical incision mohs micrographic surgery electrosurgery cryosurgery
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alternatives to surgery for basal cell carcinoma
radiation, photodynamic, topical chemotherapeutic creams
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malignant melanoma
cancerous neoplasm present in dermis and epidermis manifests as a change in nevus or a new growth on the skin color is dark, red, blue colored or a mix, irregular shape itching, rapid growth, ulceration, bleeding
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treatment of malignant melanoma
surgical excision, chemotherapy
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what to ask about with malignant melanoma
pruritus, tenderness, pain, changes in moles, or new pigmented lesions
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squamous cell carcinoma
arises from epidermis, sun damaged skin less aggressive than melanoma, can cause death may metastasize by blood or lymph rough, thickened, scaly tumor may be asymptomatic or bleed border is wide, more infiltrated, more inflammatory
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psoriatic plaques complications
infection and psoriatic arthritis
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what aggravates psoriasis
stress, trauma, seasonal and hormonal changes
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treatment of psoriasis
baths to remove scales and medications remove scales with soft brush emollient creams after maintain routine pharmacologic therapy topical phototherapy ASSESS NAIL AND SCALP
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CABG complications
Bleeding Clots Infection PNA Breathing issues Pancreatitis Kidney failure Abnormal heart rhythms Graft failure Death
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Post-op gallbladder care
low fowlers fluids and NG suction for distention soft diet when bowel sounds return avoid turning splint affected side shallow breaths analgesics to help pt turn, cough, and deep breathe ambulate
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treatment of adrenal crisis
IV glucose, fluids, electrolytes (sodium), missing steroid hormones, and vasopressors
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S&S of thrombocytopenia come from (4)
enlarged spleen, vascular occlusion, headaches, and hemorrhage
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leukemia S&S
From inadequate production of normal blood cells Neutropenia (fever and infection) Anemia (pallor, fatigue, weakness, dyspnea on exertion, dizziness) Thrombocytopenia (ecchymoses, petechiae, nosebleeds, gingival bleeding S&S from enlarged liver or spleen Hyperplasia of gums and bone pain from expansion of marrow
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HIV encephalopathy early mani
Memory deficits, HA, difficulty concentrating, confusion, psychomotor slowing, apathy, and ataxia
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HIV encephalopathy late mani
global cognitive impairments, delay in verbal responses, vacant stare, spastic paraparesis, hyperreflexia, psychosis, hyperreflexia, tremor, incontinence, seizures, mutism, and death
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herpes virus presentation
Blisters, painful and can take 2-4w to heal, or asymptomatic Itching and pain on infected area, red and edematous May begin with macules and papules and progress to vesicles and ulcers Labia is usually primary site Men is usually foreskin, glans penis, or shaft Inguinal lymphadenopathy (groin lymph nodes), minor temp, malaise, HA, myalgia (muscle aches), dysuria
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herpes virus treatment
No cure Relieve symptoms Prevent spread of infection, make pt comfy, decrease health risks, counseling Oral antivirals (acyclovir, valacyclovir, famciclovir) can suppress symptoms and shorten course of infection Antispasmodics and saline compress
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tamponade nursing actions
IV fluids for hypotension chest x-ray or ECG prep pt for pericardiocentesis monitor hemodynamic pressures monitor heart rhythm, changes indicate improper needle position monitor for dyspnea and give O2 prn