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Flashcards in Final Exam Material Deck (234)
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1

What are the 4 genera of the family Rhabdoviridae

-Lyssavirus
-Vesiculovirus
-Ephemerovirus
-Novirhabdovirus

2

What virus causes rabies like disease?

Lyssavirus

3

What are the virion properties of rhabdoviruses?

-RNA Virus
-Genome is single stranded, linear, negative sense RNA
-Enveloped
-Rod or cone -shaped

4

T/F Virions of rhabdovirus is not stable in the environment?

False they are relatively stable in the environment
-can withstand alkaline pH
-Sensitive to UV
-Detergent based disinfectants are effective disinfectants

5

Where does replication of rhabdoviruses take place?

Cytoplasm

6

What sp. of bats is a common reservoir of rabies virus in many parts of the world?

Silver-haired bats

7

In central and south america rabies is transmitted to cattle by what bat?

Vampire bats

8

What virus has the presence of eosinophilic intracytoplasmic inclusion bodies (negri bodies) in neurons

Rabies

9

What is the gold standard test for diagnosing rabies

Fluorescent antibody test (FAT)

10

What virus causes vesicular stomatitis?

Vesiculovirus -vesicular stomatitis virus (VSV)

11

T/F Vesiculovirus is clinically indistinguishable from other vesicular diseases of swine and cattle (e.g FMD)

True

12

T/F Vesicular lesions in horses are only characteristic of VSV infection

True

13

T/F Vesicular stomatitis is NOT a zoonotic disease?

False- it is zoonotic

14

What are the virion properties of picornavirus

-Non-enveloped, single stranded, positive sense RNA viruses
-Genomic RNA is infectious

15

Is picornaviruses stable in mucus and feces?

Yes

16

Can picornaviruses withstand strong sunlight?

Yes

17

What is an effective disinfectant of picornaviruses?

Sodium Carbonate

18

What is a distinct clinical sign of foot-and-mouth disease virus?

-Vesicles on the coronary bands and interdigital space

19

How is FMD transmitted?

-Respiratory aerosols (survives 1-2 days in human resp. tract)
-Direct contact
-Indirect contact via fomites

20

What are the clinical features of Ephemerobvirus- Bovine ephemeral fever virus

-Immediate drop in milk production
-Occasionally nasal and ocular discharge

21

What are the 3 genus in the family Reoviridae that we need to know?

-Orbivirus
-Rotavirus
-Orthoreovirus

22

Family reoviridae ; genus orbivirus causes what viruses?

-African Horse Sickness virus
-Bluetoungue virus

23

Family reoviridae; genus rotavirus causes what virus?

RVA (Group A Rotavirus)

24

Family reoviridae; genus Orthoreovirus causes what virus?

Avian Reovirus

25

Blue tongue effects what species?

Most susceptible/common host: sheep (particularly fine wool and mutton breeds that are common in Europe) and some species of Deer, such as white tail deer.

26

T/F Bluetongue is a "List A" disease of the office of international epizootics (OIE).

True

27

How is blue tongue virus transmitted?

-Arthropod (insect)-borne transmission (major route of transmission)
-Transmitted biologically by certain species of Culicoides, a genus of biting midge

28

What are some of the less significant routes of transmission of blue tongue virus?

-Trans-placental transmission
-Venereal transmission

29

Clinical findings of BTV in sheep

-Cyanosis, necrotic ulceration of tongue
-Erosion of dental pad, Necrosis, Hyperemia, Ulceration in oral cavity.
-Coronitis and Laminitis causing lameness
-Extensive facial swelling
-Aborted, macerated fetus

30

How to prevent BTV?

-Vaccination: attenuated vaccine.
-Vector control
-Reduce exposure to biting insects
-Slaughter of sick or viremic animals