Final Exam - NSAIDs/Anti-Inflam Flashcards
The nurse is taking care of patients taking ibuprofen. Which of the following should be included in her assessment?
A) BP & bowel sounds
B) Weight/appetite
C) Muscle strength & ROM
D) RR, depth, rhythm
A) BP & bowel sounds - b/c NSAIDs are associated with hypertension & GI upset. All other options are not relevant
Upon checking the med chart, the nurse found out that his patient is taking both acetaminophen & furosemide. Which of the following interventions is an appropriate nursing action for these two drugs?
A) Administer meds as they are b/c they enhance drug actions
B) Measure patient’s I/O closely
C) Arrange for SGPT monitoring
D) Assess for signs & symptoms of bleeding
B) Measure patient I/O closely - b/c Acetaminophen can decrease the diuretic effect of loop diuretics so it is important to monitor patient fluid retention
Which of the following patient manifests acetaminophen toxicity?
A) Marie, 26, w/ new-onset jaundice while on drug therapy
B) Eva, 54, w/ difficulty of breathing while on drug therapy
C) Steven, 37, w/ joint stiffness while on drug therapy
D) Robert, 29, w/ new-onset glaucoma while on drug therapy
A) Marie, 26, w/new-onset jaundice while on drug therapy
b/c Acetaminophen toxicity manifests as severe hepatotoxicity
Which enzyme is found in active sites of trauma or injury?
A) Streptokinase
B) COX-1
C) Alpha-ketoglutarate
D) COX-2
D) Cox-2
b/c The presence of this enzyme in active sites of trauma prompts increase in prostaglandins. NSAIDs block COX-2 before signs & symptoms of inflammation can develop
The patient asked the nurse of how soon pain relief will be achieved after a dose of IV NSAIDs. The nurse would be correct by answering:
A) 5-10 minutes depending on the site involved
B) At the start of the infusion
C) 30 minutes since pain is usually extensive
D) At the first hour of infusion
B) At the start of infusion
b/c onset of action of NSAIDs is immediately after infusion. In oral form, onset is 30 minutes after administration
Which of these lab values would indicate toxicity in a patient taking acetaminophen daily?
A) Direct bilirubin level of 2mg/dl
B) Platelet count of 400,000mm3
C) Sodium level of 140mEq/L
D)Prothrombin time of 12 seconds
A) Direct bilirubin level of 2mg/dl
B/C bilirubin level of 2mg/dL or greater indicates acetaminophen toxicity (hepatotoxicity)
Which of the following is an antidote for opioid overdose?
A) Flumazenil
B) Glucagon
C) Naloxone
D) N-acetylcysteine
C) Naloxone
B/C Naloxone is the antidote for opioid overdose by competitively binding to u-opioid receptors.
Flumazenil is an antidote to benzodiapines. Glucagon is an antidote for beta blocker overdose. N-acetylcysteine is an antidote for acetaminophen.
Which of the following OTC analgesics is one of the most common causes of liver failure in the USA?
A) Naproxen
B) Acetaminophen
C) Ibuprofen
D) Aspirin
B) Acetaminophen
B/C Acetaminophen in doses over 3000mg per day can result in significant liver damage or failure.
