Final Part 2: Glucose Flashcards

(63 cards)

1
Q

What is glycogen synthase used for

A

Glycogen storage

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2
Q

When is glycogen phosphorylase active

A

During exercise

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3
Q

What is glycogen phosphorylase used for

A

Energy release

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4
Q

What is produced during high-intensity exercise

A

Lactate

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5
Q

What is the misconception about lactate

A

It causes cramps but that is false

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6
Q

What type of exercise reduce blood glucose

A

Low-Intensity

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7
Q

What type of exercise incease blood glucose

A

High-intensity

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8
Q

Why does high-intensity training results in increased glucose

A

Because of adrenaline

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9
Q

What type of diabetes is developped over time?

A

Type 2

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10
Q

What are 2 risk factors of type 2 diabetes

A

Obesity and Inactivity

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11
Q

What is type 2 diabetes characterized by

A

Insulin resistance and high blood sugars

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12
Q

What does type 2 diabetes damage

A

Blood vessels

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13
Q

What is an indicator of type 2 diabetes

A

Excessive thirst and frequent urination

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14
Q

What are 3 ways to measure blood glucose

A

1) HbA1c
2) OGTT
3) Euglycemic hyperinsulinemic clamp

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15
Q

Which of the tehcniques to measure blood glucose reflect long-term glucose control levls

A

HbA1c

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16
Q

What is the gold standrad for insulin sensitivity testing

A

Euglycemic clamp

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17
Q

What medication is used to treat type 2 diabetes

A

Metformin

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18
Q

What does metformin improve

A

Insulin sensitivity

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19
Q

What medication is GREAT to manage type 2 diabetes but leads to loss of muscle mass

A

GLP-1 (semaglutide)

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20
Q

What do semaglutides help with

A

1) Weight loss
2) Improve glucose control

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21
Q

What is type 1 diabetes

A

Autoimmune disorder that destroy beta cells

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22
Q

When is type 1 diabetes most often detected

A

Adolescence

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23
Q

What other factor can VERY RARELY trigger type 1 diabetes

A

An extreme trauma/stress

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24
Q

What is the main issue surrounding type 2 diabetes

A

One can’t absorb glucose properly

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25
What is the main issue surrounding type 1 diabetes
One can't produce insulin
26
What is required for glycogen to get to the liver and muscle
Body tranferers
27
What are the ONLY two ways to get Glut4 or Glut2 to the surface of the liver
1) Insulin 2) Muscle contraction
28
What does stravation do
Loose muscle mass and you use your muscles as a source of energy
29
When you starve do you have a higher MPS or MPB
MPB
30
What is glucose utilization
Break down glucose and use it as a source of energy
31
What is always needed to complete the reactions associated with glucose to allow one to use glucose as a source of energy
2 enzymes - 6 phosphate - Hexokinase
32
What is an indicator of an enzyme
It ends with ''ase''
33
What are enzymes refered to
Scissors
34
If the glucose is already in the cell do you need both enzymes to use glucose
No, only 6 phosphate
35
Do you need to be done eating food completely to secrete insulin
No, there are sensors in your tongue they indicate that food is coming hence the body needs to start secreting insulin.
36
How fast after exercise do lactate levels go back to normal
30 minutes
37
What are cramps created by
Neuromuscular system
38
What molecules are cramps associated with (not lactate)
How calcium is used in the body
39
True or false, there is a direct link between higher blood lactate and soreness
False, there is a correlation between higher blood lactate and soreness but not a direct link
40
When does plasma glucose increase
With activity intensity increase
41
During studies of plasma glucose, why did they only draw blood at the end of the exercise training
Hard to draw blood as participants are running very fast
42
What was an interesting finding of the study on plasma glucose and insulin
During exercise, there is no increase in insulin levels. The peak is only present right after the exercise
43
What does a spike in adrenaline do
Blocks the production of insulin
44
When do you have the highest glucose levels
During sprinting
45
What measures the amount of glucose attached to your red blood cells
HbA1c
46
How long does HbA1c measure glucose
Last 3 months
47
What is an advantage of HbA1c
Gives a great average of glucose levels as glucose levels changes really fast in our day to day life.
48
What can reduce type 2 diabetes to zero
LIFESTYLE CHANGES
49
What are two risk factors of getting type 2 diabetes
Insulin disorder or resistance
50
What is one way to control your type 2 diabetes
Don't eat as much foods that will spike your glucose levels, also known as foods with low glycemic index
51
Is a low insulin sensitivity good or bad
Bad
52
What will a low insulin sensitivity lead to
High insulin resistance
53
What is a serious complication from type 2 diabetes
Amputation because the blood vessels are affected and no nutrients are able to reach the tissues.
54
What is the delay from measuring blood glucose from the skin
15 minutes
55
What is the best insulin test you can use
Skin measurements
56
What does Metformin medication do
Lowers blood sugar
57
In type 2 diabetes what was found in a study that had to do with lifestyle changes and metformin
Lifestyle changes itself had more improvement than metformin did. It decreased diabetes by half.
58
What does decrease weight also decrease
1) Insulin sensitivity 2) Bone density
59
How can you conserve your BD during rapid weight loss
Do resistance training (protects over half)
60
What is HMB
Important supplement in maintaining BD and muscle mass
61
In olrder adults, which exercise (aerobic or resistance) is the key to longevity and better functionality
Resistance
62
What exercise is great for patients with type 1 diabetes and why
10-s maximal sprint as sprints increases glucose levels and can avoid hypoglycemia
63
What should a person with type 1 diabetes always carry
Carbs