First Aid: pscyhopharmacology

Question 1

first-line treatment for extrapyramidal symtpoms caused by antipsychotics

Answer 1

Benztropine

Question 2

tardive dyskinesia

Answer 2

grimacing and tongue protrusion

Question 3

acute dystonia

Answer 3

intermittent spasmodic or sustained involuntary contractions of muscles in the face, neck, trunk, pelvis, extremities, and even the larynx.

Question 4

Akathisia

Answer 4

restlessness

Question 5

bradykinesia

Answer 5

slow body movement

Question 6

common side effect of anticholinergic medication

Answer 6

constipation

Question 7

Anticholinergic medications exacerbate what disorders

Answer 7

neurocoginitive (dementias)

Question 8

HAM side effects

Answer 8

1. antihistamine: sedation, weight gain
2. antiadrenergic: hypotension
3. antimuscurinic: dry mouth, blurred vision

Question 9

which drugs have HAM side affects

Answer 9

1. TCAs

2. low-potency antipsychotics

Question 10

drugs that cause serotonin syndrome

Answer 10

SSR

MOAI

Question 11

What is hypertensive crisis

Answer 11

buildup of stored catecholamines

Question 12

what causes hyperprolactinemia

Answer 12

1. high potency typical antipsychotics

2. risperidone

Question 13

CYP450 inducers

Answer 13

• tobacco
• carbamazepine
• barbituates
• St. John wort

Question 14

CYP450 inhibitors

Answer 14

• FLuvoxamine
• Fluoxetine
• Paroxetine
• Duloxetine
• Sertaline

Question 15

CYP450 inhibitors do what to drugs

Answer 15

increase drug levels

Question 16

CYP450 inducers do what to drugs

Answer 16

decrease drug levels

Question 17

What percent of patients respond to anti-depressants

Answer 17

60-70

Question 18

Longest half life SSRI

Answer 18

Fluoxetine

Question 19

SSRI with highest GI upset

Answer 19

Sertaline

Question 20

which SSRI is the only drug approved for OCD

Answer 20

Fluvoxamine

Question 21

Black box warning for SSRI drugs

Answer 21

suicidal thinking and behavior in children and young adults

Question 22

Side effect of SNRI

Answer 22

increase blood pressure

Question 23

why would you perscribe Bupropion over SSRI

Answer 23

lack of sexual side effects

Question 24

Black box warning for Nafezodone

Answer 24

serious liver failure

Question 25

what is prescribed to elderly patients for treating major depression and helps with sleep and appetite

Answer 25

Mirtazapine

Question 26

TCA used to treat OCD

Answer 26

Clomipramine

Question 27

TCA used to treat enuresis

Answer 27

Imipramine

Question 28

treatment for overdose TCA

Answer 28

sodium bicarbonate

Question 29

3 C side effects of TCA

Answer 29

Cardiotoxicity Convulsoins Coma

Question 30

Depression with atypical features, characterized by hypersomnia, increased appetite, leaden paralysis, and increase sensitivity to inerpersonal rejection. Treatment?

Answer 30

MOAI

Question 31

MOA for MAOI

Answer 31

irreversibly inhibits enzymes MAO-A and B

Question 32

treatment for serotonin syndrome

Answer 32

1. discontinue medication 2. Benzo and supportive care 3. cyproheptadine

Question 33

warning with atypical antipsychotics for elderly

Answer 33

all-cause mortality and stroke

Question 34

side effect profile for low potency typical antipsychotics

Answer 34

antiadrenergic anticholinergic antihistaminic

Question 35

how is high-potency antipyschotics given to the patient? which ones

Answer 35

intramuscular - haloperidol - fluphenazine

Question 36

what dopamine pathway is blocked for treatment of positive symtpoms

Answer 36

mesolimbic

Question 37

what causes negative symptoms of schizophrenia

Answer 37

mesocortical

Question 38

what causes extrapyramidal symptoms

Answer 38

nigrostiatum

Question 39

treatment for akathisia

Answer 39

beta blockers and benzos

Question 40

dystonia

Answer 40

sustained painful contraction of muscles

Question 41

who is at an increased risk for getting tardive dyskinesia

Answer 41

women and patients with affective disroders

Question 42

Which antipsychotic is shown to decrease risk of suicide

Answer 42

Clozapine

Question 43

Lurasidone treats

Answer 43

bipolar depression

Question 44

Therapuetic range for lithium

Answer 44

.6-1.2

Question 45

Anticonvulsants are good at treating

Answer 45

mixed features and rapid-cycling bipolar disorders

Question 46

main side effects of carbamazapine

Answer 46

Stevens-Johnson syndrome | Teratogenic: neural tube defects

Question 47

Use for lamotrigine

Answer 47

bipolar depression

Question 48

side effect of Lamotrigine

Answer 48

stevens-johnson syndrome

Question 49

Side effect of topiramate

Answer 49

weight loss | cognitive slowing