First Aid Psychiatry: Neuro Flashcards
(41 cards)
What is the ICU triad
delirium
pain
agitation
is delirium a medical emergency
yes
Most common precipitants of delirium in children are
febrile illness and medications
EEG for delirium
diffuse slow EEG
what does EEG show for delirium tremens
nothing
quick bedside am for substance/medication intoxication
VALEUMS vitals alertness Eyes Urine mucous membrane skin
what happens to memory in delirium
deficits in recent memory
What is used to rule diagnose delirium
Confusion Assessment Method
How is delirium treated
treat the underlying cause
drug of choice for Delirium
Haloperidol
what drugs are contraindicated in delirium
second generation antipsychotics
Benzodiazepines (only used in alcohol delirium)
Name 2 tests for diagnosis for neurocognitive disorder
Mini Mental State Exam
Mini-Cog
how does hyperthyroidism show in the elderly
apathetic thyrotoxicosis: depression and lethargy
Most common underlying etiology of major neurocognitive disorder
Alzheimer
cognitive domains impacted by Alzheimer
memory
learning
language
what is found in brain of Alzheimer
senile plaques and neurofibrillary tangles
- extraneural beta-amyloid plaques
- intraneural tau protein tangles
how does Alzheimer start
gradual cognitive decline
genes predisposing to Alzheimer
Amyloid precursor protein
presenilin 1
Presenilin 2
EPO4
treatment for Alzheimer
- Cholinesterase inhibitors
- NMDA receptor antagonist
- antipsychotics: increased mortality
antipsychotics carry a black box warning for what in patients with dementia
increased risk of death
how does vascular disease present
complex attention and executive function
- stepwise deterioation
- acute onset follow by partial improvement
- insidious onset with gradual decline
core features of Lewy Body
- waxing and waning of attention and alertness
- visual hallucinations
- extrapyramidal signs
Suggestive features of Lewy body
- REM sleep behavior disorder
- antipsychotic sensitivity
pathology of Lewy Body
Lewy bodies: alpha-synuclein
Lew Neurites
- both in basal ganglia