First Aid Psychiatry: Neuro Flashcards

(41 cards)

1
Q

What is the ICU triad

A

delirium
pain
agitation

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2
Q

is delirium a medical emergency

A

yes

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3
Q

Most common precipitants of delirium in children are

A

febrile illness and medications

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4
Q

EEG for delirium

A

diffuse slow EEG

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5
Q

what does EEG show for delirium tremens

A

nothing

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6
Q

quick bedside am for substance/medication intoxication

A
VALEUMS
vitals
alertness
Eyes
Urine 
mucous membrane
skin
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7
Q

what happens to memory in delirium

A

deficits in recent memory

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8
Q

What is used to rule diagnose delirium

A

Confusion Assessment Method

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9
Q

How is delirium treated

A

treat the underlying cause

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10
Q

drug of choice for Delirium

A

Haloperidol

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11
Q

what drugs are contraindicated in delirium

A

second generation antipsychotics

Benzodiazepines (only used in alcohol delirium)

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12
Q

Name 2 tests for diagnosis for neurocognitive disorder

A

Mini Mental State Exam

Mini-Cog

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13
Q

how does hyperthyroidism show in the elderly

A

apathetic thyrotoxicosis: depression and lethargy

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14
Q

Most common underlying etiology of major neurocognitive disorder

A

Alzheimer

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15
Q

cognitive domains impacted by Alzheimer

A

memory
learning
language

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16
Q

what is found in brain of Alzheimer

A

senile plaques and neurofibrillary tangles

  • extraneural beta-amyloid plaques
  • intraneural tau protein tangles
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17
Q

how does Alzheimer start

A

gradual cognitive decline

18
Q

genes predisposing to Alzheimer

A

Amyloid precursor protein
presenilin 1
Presenilin 2
EPO4

19
Q

treatment for Alzheimer

A
  1. Cholinesterase inhibitors
  2. NMDA receptor antagonist
  3. antipsychotics: increased mortality
20
Q

antipsychotics carry a black box warning for what in patients with dementia

A

increased risk of death

21
Q

how does vascular disease present

A

complex attention and executive function

  • stepwise deterioation
  • acute onset follow by partial improvement
  • insidious onset with gradual decline
22
Q

core features of Lewy Body

A
  1. waxing and waning of attention and alertness
  2. visual hallucinations
  3. extrapyramidal signs
23
Q

Suggestive features of Lewy body

A
  • REM sleep behavior disorder

- antipsychotic sensitivity

24
Q

pathology of Lewy Body

A

Lewy bodies: alpha-synuclein
Lew Neurites
- both in basal ganglia

25
treatment Lewy Body
1. cholinesterase inhibitor 2. Quetiapine or clazapine 3. levodopa/carbidopa 4. Melatonin/clonazepam
26
clinical manifestation for Frontotemporal degeneration
cognitive deficits in attention, abstraction, planning, and problem solving - difficult speech and comprehension
27
treatment for frontotermpaol degeneration
Serotnergic medications my help
28
name an infection that can cause neurocognitive deficiency
HIV
29
treatment of HIV
- Highly active antiretroviral therapy | - psychostimulants
30
Triad of Huntington clinical manifestation
1. Motor: chore and bradykinesia 2. cognitive: executive function 3. psychiatric
31
Treatment of Huntington
Tentrabenzine or atypical antipsychotics
32
How is Parkinson's diagnosed
1. Bradykinesia : tremor or ridigity 2. asymmetry of motor symptoms 3. cognitive decline appears after onset of motor symptoms
33
treatment for Parkinsons
1. carbidop/levodopa 2. cholinesterase inhibitor 3. Queitipine or clozapine (low dose)
34
symptoms of Parkinson's disease can be exacerbated by what medication
antipsychotics
35
pathology of prion disease
spongiform encephalopathy
36
most common type of prion disease
Creutzfeldt-Jakob disease
37
clinical features of prion diseae
- rapid progression - concentration, memory, and judgment first to go - myoclonus - ataxia, nystagmus, and hypokinesia
38
EEG for prion disease
periodic sharp wave complexes
39
lesions occur where in brain for prion disease
putamen or caudate nucleus
40
what does lumbar puncture show for normal pressure hydrocephalus
- normal opening pressure | - elevation of CSF
41
treatment for normal pressure hydrocephalus
shunt