FLUID AND ELECTROLYTE IMBALANCES Flashcards

(138 cards)

1
Q

y constantly adjusting to
internal and external stimuli.

A

Homeostasis

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2
Q

EXAMPLES OF HOMEOSTASIS IN THE BODY

A

Thermoregulation
● Blood glucose regulation
● Baroreflex in blood pressure

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3
Q

property of particles in a solution to
dissociate into ions

A

OSMOLARITY

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4
Q

Enhances or intensifies the original stimulus

A

POSITIVE FEEDBACK

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5
Q

reverses an original stimulus
for the body to regain physiologic balance.

A

NEGATIVE FEEDBACK

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6
Q

Maintains homeostasis through feedback loops. Using

A

nerves and neurotransmitters

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7
Q

Blood clotting after an injury -
what kind of feedback?

A

positive

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8
Q

Blood pressure control
-Maintenance of normal body
temperature

kind of feedback?

A

Negative

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9
Q

major cations in the body fluid are

A

sodium, potassium, calcium, magnesium,
and hydrogen ions

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10
Q

major anions are

A

chloride,
bicarbonate, sulfate, and proteinate ions.

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11
Q

intracellular fluid refers to all fluids including

A

cytosol as well as fluid in the cell
nucleus.

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12
Q

stimulates or
inhibits the desire for a person to drink

A

thirst center in the hypothalamus

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13
Q

regulates the amount of water the kidney tubules
absorb and is released in response to low blood
volume

A

ADH ANTIDIURETIC HORMONE

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14
Q

controls fluid volume, in which when
the blood volume decreases

A

RENIN ANGIOTENSIN ALDOSTERONE SYSTEM (RAA SYSTEM)

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15
Q

heart also plays a role in correcting overload
imbalances by releasing

A

ANP from the right atrium.

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16
Q

series of
interconnected brain structures that act as a central
hub to control fluid levels in the body

A

lamina terminalis (yellow)

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17
Q

fluid-filled compartments in the brain, called

A

ventricles (blue).

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18
Q

ADH known as

A

VASOPRESSIN

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19
Q

ability of a membrane to allow molecules to pass
through.

A

PERMEABILITY

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20
Q

membranes allow almost any food or waste
substance to pass through.

A

PERMEABILITY OF MEMBRANES FREELY PERMEABLE MEMBRANES

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21
Q

only certain specific
substances to pass through.

A

SELECTIVELY PERMEABLE

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22
Q

from an area of higher
concentration to an area of lower concentration.

A

DIFFUSION

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23
Q

transport of water and dissolved materials
concentration already exists in the cell.

A

FILTRATION

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24
Q

ACTIVE TRANSPORT MECHANISMS examples

A

Phagocytosis of bacteria by Macrophages.
● Movement of Ca?* ions out of cardiac muscle cells.
● Transportation of amino acids across the intestinal
lining in the human gut.

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25
urine output of male, female and infant
Male void - 300 - 500ml/day ● Female void - 250 ml/day ● Infants void - 5-40 Xa day ● Preschool children are void - every 2 hrs.
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are the body's major chemical buffers.
Sodium bicarbonate and carbonic acid a
27
e basic components in the body, and the kidneys
Bicarbonate ions
28
change in the pH of a solution by one pH unit means a
tenfold change in hydrogen concentration.
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causes high anion gap metabolic acidosis and respiratory alkalosis.
Aspirin
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CO2 or HCO3 normal
Uncompensated:
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: Nothing is normal in abg
Partially Compensated:
32
pH is normal (7.4 baseline/neutral)
Compensated
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values for Sodium Potassium Calcium Magnesium Phosphate
S: 135-145 mEq/L P: 3.5-5.0 mEq/L C: 8.8.-10.4 mg/dL M: 1.8-2.6 mg/dL P: 3.4-4.5 mg/dL
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SIADH means
/ SYNDROME OF INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE
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DISORDER OF IMPAIRED WATER EXCRETION CAUSED BY THE INABILITY TO SUPPRESS THE SECRETION OF ANTIDIURETIC HORMON
SIADH
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treat hyponatremia by stimulating free water excretion.
AVP receptor agonists.
37
decrease fluid volume in FVE,
Diuretics.
38
If serum potassium levels are dangerously elevated, it may be necessary
IV calcium gluconate
39
used to lower the serum calcium level and is particularly useful for patients with heart disease
Calcitonin.
40
enhance conservation of water by increasing the permeability of collecting ducts to water
Avp/ Vasopressin is a vasopressin receptor agonist
41
predisposing factors of FLUID VOLUME DEFICIT (FVD)
Diabetes Insipidus ● Adrenal insufficiency ● Osmotic diuresis ● Hemorrhage ● Coma
42
movement of fluid from the vascular system to other body spaces f
Third-space fluid shifts o
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SIGNS AND SYMPTOMS of FVD (INFANT AND YOUNG CHILDREN)
Crying without tears ● No wet diapers for three hours or more ● Being unusually sleepy or drowsy
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Decreased ability to concentrate urine due to ADH deficit or nephron resistance to ADH
Diabetes Insipidus
45
decreased PLASMA VOLUME and makes the RBCs concentrated
increase Hematocrit level
46
Elevated BUN indicates?
out of proportion with creatinine Because Urea
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Appearance of wakefulness, awareness of the self and environment
ALERT (CONSCIOUS)
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mild reduction in alertness
LETHARGY
49
moderate reduction in alertness. Increased response time to stimuli
OBTUNDATION
50
aroused only by vigorous and repetitive stimulation.
STUPOR
51
(Unarousable unresponsiveness, eyes closed)
COMA (UNCONSCIOUS)
52
a measure of pressure in the vena cava, can be used as an estimation of preload and right atrial pressure.
CENTRAL VENOUS PRESSURE
53
NORMAL Central venous pressure?
2-5 mmHg
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3 STAGES OF HYPOVOLEMIC SHOCK
Stage 1: 15% blood loss (750 mL or about 25 ounces). ● Stage 2: 15% to 30% (750 mL to 1,500 mL or up to almost 51 ounces) ● Stage 3: 30% to 40% of your blood (1,500 to 2,000 mL or up to 68 oz.)
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caused by the abnormal retention of water and sodium
HYPERVOLEMIA
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SIGNS & SYMPTOMS (PULMONARY) of FVE
Pulmonary Congestion: crackles, rales ● Change in respiratory pattern
57
buildup of, nitrogenous products
Azotemia
58
Normal urine specific gravity levels are
1.010 and 1.020
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right ventricular third heart sound. It is usually heard best where
right or left lower sternal edge, in the epigastrium, or rarely over the jugular veins
60
swelling that occurs prior to a woman's menstrual cycle
Premenstrual edema
61
disorder that causes excess excretion of protein in the urine
Nephrotic syndrome
62
major extracellular fluid cation.
Sodium (Na)
63
urine specific gravity of hypernatremia
>1.025
64
SIGNS AND SYMPTOMS (TOO MUCH SALT)
Skin flushed ● Agitation ● Low grade fever ● Thirst
65
NURSING MANAGEMENT of hypernatremia
Monitor level of consciousness, muscular strength, tone, & movement
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very brisk, hyperactive, with clonus
4+
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3+ DTR RESPONSE
Brisker than average, slightly hyperreflexic
68
2+ DTR
Average, expected response; normal
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Somewhat diminished, low normal DTR
1+
70
No response, absent
0
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SIGNS AND SYMPTOMS (LOSS) FOR HYPONATREMIA
Limp muscles ● Orthostatic hypotension ● Seizures ● Stomach cramping
72
Hypertonic 0.3% NS - slow IV infusion via central line. ***Watch out for fluid overload! Nursing managment for what type of hyponatremia
HYPOVOLEMIC HYPONATREMIA
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Caused by SIADH antidiuretic hormone problems: fluid restriction or treated with antidiuretic hormone
EUVOLEMIC HYPONATREMIA
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Restrict fluid intake and in some cases administer diuretics to excretion the extra water nursing management for what type of hyponatremia
. FOR HYPERVOLEMIC HYPONATREMIA
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antidiuretic hormone antagonists called
Declomycin (don’t give with food especially dairy or antacids
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e major cation in the intracellular fluid (ICF)
Potassium K+.
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= mild hyperkalemia
5.1 mEq/L to 6.0 mEq/L
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moderate hyperkalemia
6.1 mEq/L to 7.0 mEq/L =
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severe hyperkalemia
● above 7 mEq/L
80
increased when potassium is lost from the tissue
glycogen synthesis
81
SIGNS AND SYMPTOMS for Hyperkalemia MURDER
Muscle weakness/cramps ● Urine, oliguria, anuria ● Respiratory distress ● Decrease cardiac contractility ● EKG changes ● Reflexes ( hyper or areflexia)
82
Treatment for Hyperkalemia “C BIG K DROP”
Calcium gluconate (stabilizes cardiac membrane) ● Beta-2-agonist(albuterol neb q2-4hrs), Bicarb (shift K+ to the cell) ● Insulin ● Glucose ● Kayexalate(Na polystyrene sulfonate)- to excrete K+ out ● Drop - DIURETICS(Furosemide) - to excrete K+
83
SEVERE HYPERKALEMIA IS TREATED IN 3 STEPS CIH:
Calcium infusion Insulin Hemodialysis
84
associated with shifting of K+ into cells, K+ loss from GI and biliary tracts, renal K+ excretion and reduced K+ intake
HYPOKALEMIA
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causes kidneys to excrete K
CUSHING’S SYNDROME
86
SIGNS & SYMPTOMS (7L’S) of hypokalemia
Lethargy ● Low, shallow breathing ● Lethal cardiac arrest ● Loss of urine ● Leg cramps ● Limp muscles ● Low BP & HR
87
TREATMENT (STOP K+ LOSSES!) for Hypokalemia
Discontinue diuretics, laxatives ● Don’t give LASIX Use rather potassium-sparing diuretics /Aldactone,
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T (PREVENTION AND CORRECTION OF POTASSIUM DEFICIENCY;) ● with alkalosis
use potassium chloride
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PREVENTION AND CORRECTION OF POTASSIUM DEFICIENCY; acidosis
use potassium acetate,
90
Serum calcium is regulated by?
PTH and Calcitonin
91
important for neuromuscular activity & blood coagulation
Ionized calcium
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plasma calcium is bound to serum proteins - albumin
Bound calcium
93
the remaining plasma is combined with nonprotein ions: phosphate, citrate, & carbonate.
Complex calcium
94
SIGNS & SYMPTOMS (BACKME) hypercalcemia BACKME
Bone Pain ● Arrhythmias ● Cardiac Arrest ● Kidney Stones ● Muscle Weakness ● Excessive Urination
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S/S of Hypercalcemia too weak
Absent reflexes, disorientated, abdominal distention from constipation ● Kidney Stone formation
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most common ECG findings of hypercalcemia are
a short QT interval secondary to a shortened ST segment. There may also be a widened or flattened T wave
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hypercalcemia can cause ECG changes that mimic
acute myocardial infarction.
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Hypercalcemia has also been known to cause an ECG finding mimicking hypothermia
known as an Osborn wave ( J wave). Ventricular fibrillation and arrest for extreme hypercalcemia.
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adrenal glands above the kidneys, produces too little cortisol and too little aldosterone.
Adrenal insufficiency (Addison’s Disease)
100
decreased with Thiazide* diuretics & renal failure, cancer of the bones
Calcium excretion
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causes phosphate to decrease and calcium to increase
Lithium usage (affects the parathyroid
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COMMON MEDICATIONS AND SUPPLEMENTS THAT CAN CAUSE HYPERCALCEMIA
Hydrochlorothiazide Lithium. ● Excessive intake of vitamin D
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treatment for hypercalcemia
Forced Diuresis Loop DIURETICS Glucocorticoids:
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Saline administration will cause renal elimination/ to decrease calculi formation.
Forced Diuresis
105
reduces intestinal absorption and tubular reabsorption of calcium
Glucocorticoids:
106
refers to the total concentration of dissolved substances in drinking water
– TOTAL DISSOLVED SOLIDS TDS
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calcium deposits in the kidney that causes poor kidney function
Nephrocalcinosis -
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COMPLICATIONS OF LONG-TERM HYPERCALCEMIA
Nephrocalcinosis - Kidney failure. ● Kidney stones. ● High blood pressure (hypertension).
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determines a reduction of calcium due to a decrease in the fraction bound to proteins
Hypoalbuminemia
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reduced response of the target tissues to parathyroid hormone (PTH) and /
reduction in ionized calcium
111
SIGNS & SYMPTOMS of hypocalcemia TCT
Tetany ● Chvostek’s sign ● Trousseau’s sign
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symptom characterized by the involuntary contraction of muscles
Tetany i
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Common symptoms of tetany
umbness around the mouth, muscle cramps, a
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hallmark of acute hypocalcemia is
neuromuscular irritability
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TAPPING ON THE COURSE OF FACIAL NERVE, BETWEEN ZYGOMATIC ARCH & ANGLE OF MANDIBLE
chvostek sign
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BP CUFF WHEN INFLATED HIGHER THEN PERSON'S SYSTOLIC BP FOR ____ minutes
2 minutes: Trousseau’s sign
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SIGNS & SYMPTOMS ("CATS GO NUMB" MNEMONIC) HYPOCALCEMIA
Convulsions (seizures) ● Arrhythmias (prolonged QTc) ● Tetany ● Spasms, Stridor (laryngospasm) ● Numbness [perioral, acral (hands, feet)
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might be a collapsing of the larynx most likely caused by decalcification. I
STRIDOR
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refers to a burning or prickling sensation that is usually felt in the hands, arms, legs, or feet, b
Paresthesia
120
Hypocalcemia may lead to what ecg finding also refers to complete heart block
torsades de pointes
120
Hypocalcemia may lead to what ecg finding also refers to complete heart block
torsades de pointes
121
CAUSES (POSSIBLE CAUSES) of hypocalcemia
Hyperparathyroidism Vitamin D deficiency: Kidney failure:
122
CAUSES (CERTAIN MEDICATIONS) Hypocalcemia
Pseudohypoparathyroidism: Bisphosphonates, Hypomagnesemia: Pancreatitis:
122
CAUSES (CERTAIN MEDICATIONS) Hypocalcemia
Pseudohypoparathyroidism: Bisphosphonates, Hypomagnesemia: Pancreatitis:
123
an inherited disorder that causes your body to not respond properly to the normal amount of parathyroid hormone (PTH)
Pseudohypoparathyroidism:
124
abundant intracellular cation.
Mg++
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MAGNESIUM function
CONSTIPATION RELIEF REDUCES ECLAMPTIC SEIZURES
126
Significant symptoms and signs are seen when serum Mg is
s < 1.2 mg/dl (0.5 mmol/l)
127
Significant symptoms and signs are seen when serum Mg exceeds
4.8 mg/dl (2 mmol/l)
128
relationship of DTR and Magnesium
High DTR = Low magnesium
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phosphorus found in the extracellular fluid space is in the form of
form of inorganic phosphate.
130
HYPOPHOSPHATEMIA SIGNS & SYMPTOM
Anemia, bruising ● SZ, Coma ● Constipation ● Muscle weakness ● Hypoactive bowel sounds ● Mild: asymptomatic
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DIAGNOSIS (LAB RESULTS) phosphate
↓ phosphate ● ↑ calcium ● ↓ vitamin D ● ↑ parathyroid hormone
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causes of hypophosphatemia
Increased kidney excretion Decreased intake, absorption through GI tract Transcellular shift Insulin treatment in diabetic ketoacidosis;
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COMPLICATIONSHYPOPHOSPHATEMIA
Rhabdomyolysis, kidney dama
134
when damaged muscle tissue releases its proteins and electrolytes into the blood.
Rhabdo
135
occurs when the pituitary gland produces too much growth hormone (GH)
Acromegaly
136
TREATMENT hyperphospatemia
Calcium carbonate and calcium citrate Fluid resuscitate For acute or chronic Hyperphosphatemia: consider forced diuresis