Fluid and electrolytes Flashcards

(32 cards)

1
Q

What is the major cation and anion in intracellular fluid?

A

Potassium and Phosphate

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2
Q

What is the major cation and anion in extracellular fluid?

A

Sodium and chloride

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3
Q

What are the signs of intracellular dehydration?

A

1) Reduced skin turgor
2) Sunken eyeballs
3) Sunken fontanelle

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4
Q

What are the signs of interstitial fluid overload?

A

Pitting edema

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5
Q

What are the signs of intravascular dehydration?

A

1) ↑HR
2) ↓BP
3) ↓JVP
4) CRT >3cm
5) ↓tears
6) oliguria

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6
Q

What is the percentage body weight loss in mild, moderate and severe dehydration?

A

Mild: 3-5%
Moderate: 6-9%
Severe: >10%

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7
Q

What are the red flags for dehydration in a child?

A

1) S/S of severe dehydration including shock

2) Altered mental state
- dehydration, hypotension, uremia, acidosis, hypona, hypogly

3) Seizures
- hypoNa, hypogly

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8
Q

How is mild dehydration in children managed?

A

1) Treat cause

2) Volume= maintenance + replacement
- if can, do oral
- if cannot/dont want, consider entered tube feeding
- if cannot oral, IV fluids

3) Monitor hydration status

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9
Q

How is moderate dehydration in children?

A

1) Check complications:
- AKI
- Acid-base
- electrolytes
- glucose abnormalities

2) Determine type of dehydration

3) IV fluids dependent on type of dehydration and complications

4) Encourage oral fluid intake

5) Monitor hydration and state of complication

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10
Q

How is severe dehydration in children managed?

A

1) Fluid resus:
- IV 10-20ml/kg 0.9% normal saline and assess response

2) Determine type of dehydration

3) Check complications:
- AKI
- Acid-base
- electrolytes
- glucose abnormalities

4) Give IV fluids depending on type of dehydration of complications

5) Encourage oral fluids

6) Monitor hydration status

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11
Q

What are the 3 volumes of fluid that need to be added to the final fluid replacement in dehydration?

A

1) Maintenance fluid

2) Correction of deficit

3) Replacement of ongoing fluid loss

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12
Q

What are the 2 phases of treatment in dehydration?

A

1) Rehydration phase
- water + electrolytes rapidly within 3-4hrs

2) Maintenance phase
- restoration of ongoing losses + calories

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13
Q

When is oral rehydration therapy indicated?

A

Mild-to-moderate isonatremic dehydration (eg. viral GE)
- NOT appropriate for hypo/hyperNa

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14
Q

How is ORS ordered?

A

Rehydration: 50-100ml/kg of ORS over 4 hrs

Maintenance: 10ml/kg for each watery stool OR 2ml/kg for each vomitus

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15
Q

When is IV rehydration indicated?

A

1) Shock/severe dehydration
2) Dehydration with altered level of consiousness or severe acidosis
3) Worsening/refractory dehydration
4) Persistent vomiting
5) Severe abdominal distension and ileus
6) Hypo/HyperNa dehydration

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16
Q

What is the clinical definition of polyuria?

A

Excessive urine volume
- > 3L/day in adults
- > 2L/m2/day in children
- > 5ml/kg/hour (useful cutoff when reviewing urine output
chart)

17
Q

When should you suspect a polyuria cause other than primary polydipsia?

A

When there is thirst but polyuria rather than oliguria

(usually ↓TBW → ↑serum Osm → ↑ADH → ↑thirst and water consumption → normalised)

18
Q

What are nocturia and enuresis indicative of in polyuria?

A

Renal causes rather than polydipsia

19
Q

What are the associated symptoms of DM?

A

1) Polyuria, polydipsia
2) Polyphagia
3) Weight loss

20
Q

What are the associated symptoms of hypercalcemia?

A

1) Anorexia
2) Vomiting
3) Constipation

21
Q

What are the associated symptoms of central DI?

A

1) Visual changes
2) Headache
3) Sexual precocity
4) Hx of brain surgery/trauma

22
Q

What do the findings of weak urinary stream, large kidneys and a palpable bladder indicate?

A

Obstructive uropathy

23
Q

What does findings of a precocious puberty, neurological deficits, bitemporal hemianopia, optic atropy, papilloedema

A

Central diabetes insipidus

24
Q

What is the top differential for periorbital swelling?

A

Angioedema 2° to anaphylaxis

25
What is the top differential for localised swelling in the hands and feet?
Kawasaki disease
26
What is the top differential for localised swelling of the abdominal wall?
Peritonitis
27
What is the top differentials for localised swelling in the legs?
1) Dependent edema 2) Turner syndrome 3) Compression of IVC or common iliac veins
28
What are the red flags in a child with edema?
1) Scrotal involvement - risk of cellulitis and nec fasc 2) Rapid onset ± severe pain - DVT, angioedema, infection, peritonitis 3) Generalised edema - check CVS (CHF), Renal (nephritic syndrome), Liver (cirrhosis), GI (protein-losing enteropathy)
29
What is the definition of nephrotic syndrome?
1) Edema 2) Massive proteinuria ≥ 3g/1.73m2/24 hr ≥ 50mg/kg/24 hr ≥ 40mg/hr/m2 Urine protein/creatinine ≥ 0.2 g/mmol 3) Hypoalbuminemia - <25g/L 4) Hyperlipidemia - ↑LDL, VLDL, TGs
30
How does acute glomerulonephritis/ nephritic syndrome present?
1) Gross haematuria (cola-coloured urine) 2) Edema/fluid overload signs 3) HTN 4) Oliguria 5) ±Azotemia
31
What are the complication of acute glomerulonephritis?
1) Hypertensive encephalopathy 2) Fluid overload - acute pulmonary edema - CHF 3) Acute renal failure - uremia - hyperK - acidosis - HyperPO4, HypoCa
32