Fluids & Electrolytes Flashcards

1
Q

Organs used in Fluid Balance

A

Kidneys
Hypothalamus
Pituitary gland
Adrenal Cortex

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2
Q

What is the major filtering of fluid that needs pressure to work?

A

Kidneys

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3
Q

Electrolytes are

A

electronically charged solutes
necessary to maintain life

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4
Q

Hypothalamus gives the perception of

A

thirst

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5
Q

The posterior pituitary gland releases what

A

releases and inhibits ADH

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6
Q

ADH focuses on

A

holding and letting go of water

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7
Q

Adrenal cortex regulates

A

Na though aldosterone

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8
Q

Hydrostatic pressure is increasing

A

artery pressure

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9
Q

Functions of electrolytes

A

neuromuscular irritability
maintain the body’s osmolality
regulate acid/base
regulate the distribution of body fluids

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10
Q

Increase in hydrostatic pressure caused by

A

venous obstruction
sodium and water retention

(Heart and renal failure)

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11
Q

Hypoalbuminemia

A

decrease in plasma oncotic pressure caused by low plasma albumin

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12
Q

Inflammation and immune response happen due to what abnormal fluid movement?

A

increase in capillary permeability

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13
Q

Obstruction of lymph channels caused by

A

tumors
inflammation
surgical removal

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14
Q

Complications of edema

A

pressure injuries
infections
life-threatening to the brain, lungs, and larynx

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15
Q

What are the 4 abnormal fluid movements?

A

Increase in hydrostatic pressure
decrease in plasma oncotic pressure
Increase in capillary permeability
obstruction of lymph channels

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16
Q

Assessing electrolyte balance includes

A

-Assess overall fluid balance by monitoring daily weight, I&O
-Assess neurological status; LOC
-Evaluate sensor and motor function; neuromuscular irritability
- (LAB AND V/STRENDS)
-Look at EKF to detect changes
-Assess nutritional status (electrolytes are obtained through the food we eat)
-Evaluate health hx for medical conditions
-Evaluate medication hx for prescription or OTC drugs that can interfere

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17
Q

Daily wts and I&Os show what

A

retaining
contains PO/IV

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18
Q

What electrolyte affects an EKG?

A

Potassium

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19
Q

Homeostasis functions of electrolytes

A

Promote neuromuscular irritability
Maintain body fluid osmolality
Regulate acid-base balance
Regulate the distribution of body fluid amount of body fluid compartments

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20
Q

The ECF used what electrolytes

A

Sodium
Cloride

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21
Q

ICF

A

fluid inside the cell 2/3rd (28L)

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22
Q

Factors that influence body fluid

A

age
gender
body fat
skeleton vs muscle, bone, and skin

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23
Q

What is the percentage of total body water as proportion to body weight?
Neonate -
Infant (6 months) -
Child (5 yo) -
Adult male -
Elderly male -
Adult female -

A

80%
70%
65%
60%
50%
50%

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24
Q

What gender has more body fluid? except when?

A

men
women are pregnant

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25
What age has more body fluid?
infants
26
How does weight affect body fluid?
obese people have less body fluid than thin
27
ECF
fluid outside the cell 1/3
28
Intracellular fluid has what electrolytes
potassium and magnesium Proteins
29
ECF has what electrolytes
sodium chloride
30
What type of fluids are in ECF
Intravascular (plasma) Interstitial ( surround cells) Transcellular
31
Transcellular
works in individual way different from circulatory (pleural, spinal fluid, sweat, and digestive)
32
What fluid shifting is abnormal?
3rd spacing
33
Spacing 1 through 3
1st - normal 2nd - edema 3rd - ascites, burn edema
34
3rd spacing s/s
decreased urine output (shifted toward interstitial space) increase heart rate (compensate) decreased BP and CVP **edema increase body weight** I&O not balanced
35
What is a form of 3rd spacing?
ascites burn edema
36
Electrolyte Cations
sodium potassium calcium
37
Electrolyte Anions
bicarbonate chloride phosphate
38
What are the different types of fluid regulators?
osmosis and osmolarity diffusion filtration sodium-potassium pump
39
Osmosis
spontaneous passage of water or other solvents through a permeable membrane
40
Diffusion
from higher to lower concentration
41
Filtration
high pressure to lower pressure
42
Sodium-Potassium Pump
maintains normal sodium levels by active transport
43
Output
kidney Skin(1L an hour) Lungs GI Tract (100-200mL)
44
Sodium does what
SUCKS
45
What is the primary regulator of body fluid?
sodium
46
Where sodium goes
water flows
47
What is the major electrolyte in ECF?
sodium
48
If sodium is low, then serum osmolality is
low visa versa
49
Lab Value of NA
135-145
50
If you have a decrease in serum Na, the ECF becomes
dilutes H2O drawn into cells
51
If you have an increase in serum Na, the ECF becomes
concentrated ECF H2O pulled out of the cells
52
When NA moves into cells, it kicks what out
K
53
When serum sodium increases and ECF becomes concentrated, what is stimulated?
Thirst by hypothalamus
54
Thirst stimulates ________ released from the pituitary gland.
ADH
55
What does ADH do to the kidneys?
conserve water
56
The adrenal gland releases
aldosterone in which the kidneys conserve water and sodium Increases ECF
57
Sodium is followed by
chloride and water
58
Chloride functions
maintains **electrical neutrality** osmotic gradient
59
I&O OF Na
Intake = diet Outtake = kidneys
60
Function of Na
-electrochemical state of muscle contraction and nerve impulses **BP** (ECF vol and encloses water distribution with chloride - affects the concentration and absorption of K and Cl) **Blood volume** **PH balance**
61
Na is regulated by
ADH Thirst Aldosterone (RAAS) Sodium Potassium Pump
62
ADH is also known as what drug
vasopressin
63
ADH does what
controls water retention
64
Aldosterone
hold Na inside the body by blocking it at the kidney - causes kidneys to maintain water and sodium to keep BP up - releases if sodium is low and K is high (to excretion K)
65
Sodium and Potassium Pump
moves NA out of the cells via ATP -provides energy through muscle and energy and removes acid
66
Sodium and Potassium Pump uses what to move Na out
ATP
67
HYPONATREMIA Causes (NO Na)
-Na excretion with renal problems, NG suction, vomiting, diuretics, sweating, diarrhea, - a decrease of aldosterone secretion (fluid stays) -Overload of fluid (Congestive Heart Failure, renal failure, hypotonic fluid infusion) -Na intake is low (low salt diet, NPO) -Antidiuretic hormone (SIADH)
68
Hyponatremia s/s depend on the _____, ______,and _____ at which deficit occurs
cause magneitude speed
69
What mnemonic is used as Hyponatremia S/S?
SALT LOSS
70
Hyponatremia S/S SALT LOSS
**Seizures** and stupor **Abdominal cramping**, attitude confusion **Lethargic** Tendon reflexes diminished, and trouble concentrating **Low urine** and appetite Orthostatic hypotension, **overactive bs** **Shallow respirations (late due to skeletal weakness)** **Spasms** of muscles
71
Is your hyponatremic pt a fall risk
yes, confusion = fall risk
72
Hyponatremia lab values
**Low Labs** Serum Na+ < 135 mEq/L Serum osmolality < 280 mOsm/kg Urinary Na+ < 20 mEq/L Urine specific gravity < 1.010
73
Treatment of Hyponatremia - watch for?
Na replacement (PO, NGT, IV) Depends on the rate of loss (LR, NS) - Watch for fluid overload/pulmonary edema
74
If a nurse is giving sodium to a hyponatremic pt too quickly, what should you watch out for?
neurological damage -cerebral edema
75
**Rule of Thumb for NA replacement**
serum Na must **not** be **increased greater than 12 mEq/L in 24 hours**
76
What solutions are used to tx as Hyponatremia?
Lactate Ringers Normal Saline
77
Medical Tx for hyponatremia due to water gain
GOAL: slowly elevate Na until seizures, lethargic, stupor are gone **restrict fluids** safer than giving Na hypertonic solution 3-5% NaCl (if neuro problem - give small amounts) edema only - restrict Na edema and Na - restrict both **Loop Diuretics (Lasix) with IV fluids**
78
Loop diuretics induce isotonic diuresis w/o further
hyponatremia
79
Nursing Interventions for Hyponatremia
Identify pt. at risk (**Lithium pts)** Monitor labs, I&O, daily weight Review medications GI manifestations Monitor for S/S of hyponatremia Monitor for **neurological changes Oral hygiene (restrict fluids)**
80
If a pt is at risk of a seizure, what are some precautions that need to be taken?
fall precaution mats **Suction**
81
Lithium patients with low Na can cause them to go into
lithium toxicity with urinary sodium loss
82
HYPERnatremia lab values
greater than 145
83
Hypernatremia ____ fluid _____ of the cells
pulls fluid out
84
Primary protection of Hypernatremia
Thirst
85
HYPERnatremia mnemonic
HIGH SALT
86
HIGH SALT HYPERnatremia Causes
Hypercortisolism (Cushing's, hyperventilation) Increased intake of sodium GI feeding w/o adequate water supplements Hypertonic solutions (Na is more than isotonic Sodium excretion decreased and corticosteroids Aldosteronism Loss of fluids (infection, sweating, diarrhea, DI) Thirst impairment
87
Hypernatremia S/S mnemonic
No FRIED foods for you!
88
Hypernatremia S/S
-Neuro- Fever, flushed skin Restless, really agitated Increased fluid retention Edema, extremely confused Decreased urine output, dry mouth/skin
89
Hypernatremia lab value
**High Numbers** Serum Na+ > 145 mEq/L Serum osmolality > 300 mOsm/L Urine specific gravity > 1.015
90
Hypernatremia Treatment
**decrease Na gradually** decrease 0.5-1 L/ hr over 48 hours Monitor for neuro changes and **cerebral edema** **Hypotonic solutions (D5W or 1/2 NS)** **Desmopressin for DI**
91
What medication would you use to treat hypernatremia if the underlying factor is DI?
Desmopressin
92
Nursing Interventions for Hypernatremia
Identify pt at risk (ELDERLY and INFANTS, confused, trauma, post-op, burn, immobile) Monitor fluid loss/gain **Daily wt** Labs ORAL Na Intake(processed, canned, frozen) Neuro precautions and behavior changes Offer fluids Note medication with high Na+ content
93
What medications have high Na content?
Alka-seltzer
94
Pathway of Potassium
Intake: diet Absorbed: Kidneys Excreted: kidneys/bowels
95
Normal lab values Potassium
3.5-5
96
Potassium functions
**skeletal and cardiac muscle** activity Sodium/Potassium Pump
97
What is the major electrolyte of intracellular fluid?
Potassium - it can be found in ECF
98
How is K obtained? absorbed? and excreted?
diet intestines kidneys/bowels
99
What meds could affect K?
diuretics laxatives antibiotics parental nutrition chemo
100
Potassium enriched foods
Bananas Watermelon White beans Spinach Avocado Sweet potatoes
101
What percentage of K is excreted by the kidneys?
80
102
Does the body conserve K?
no even with a deficit
103
What system is important in keeping balanced potassium?
renal body does not conserve potassium
104
Hypokalemia Causes mnemonic
Body is going to DITCH potassium
105
Hypokalemia Causes
Drugs (diuretics, laxatives, insulin, corticosteroids) Inadequate consumption of K Too much water intake (IV fluids w/o K) Cushing's syndrome Heady fluid loss (GI, V/D, SUCTION)
106
What is the number 1 reason of hyperkalemia?
renal failure
107
Cushing's disease
tumor on the pituitary gland makes too much ACTH. In response, adrenal glands produce too much cortisol. This causes problems with your body's hormone balance.
108
What drugs cause hypokalemia?
**diuretics** laxatives insulin corticosteroids
109
Hypokalemia S/S mnemonic
SLOW LOW
110
Hypokalemia S/S SLOW/LOW
Weak, irregular pulses Orthostatic hypotension **Arrhythmias** **Shallow respirations Confusion, weak** Deep tendon reflexes decreased Decreased bowel sounds Lethargy (confusion) Low, shallow respirations **Lethal cardiac dysrhythmias** Lots of urine Leg** cramps** Limp muscles **Low BP** & Heart
111
Renal loss of K
loop diuretics with potassium hyperaldosteronism high dose of sodium PCNs large dose corticosteroids
112
Digoxin does what to the heart
contracts
113
Hypokalemia at risk pts
elderly
114
Hypokalemia -Cardiac Changes-
low strength of contraction Myocardium irritability **extra beats** ST segment depression K+ < 2.7 mEq/L may result in PACs, PVC's, V-fib or cardiac arrest K+ < 3.5 assoc. with met. alkalosis, high pH & high HCO3 **Digoxin toxicity**
115
Digoxin and low K do together
potentiate so best not to usually give buth meds
116
Hypokalemia lab values
K+ deficit < 3.5 mEq/L K+ < 3.5mEq/L often assoc. with metabolic alkalosis, high pH, & high HCO3 **K+ < 2.7 may result in dangerous dysrhythmias** high pH & HCO3
117
Hypokalemia Treatment
K replacement (PO/IV) Increase on a daily basis (40-80 a day) at-risk pt (50-100 a day) potassium-rich foods treat underlying cause
118
Oral K Supplements
minimize GI irritation - **dilute liquid** and effervescent supplement - give tabs and caps q/ 8 oz water - give K **with food**
119
Adverse reactions of K oral supplements
N/V/D GI bleed
120
IV K supplements
Must be diluted Check K before giving K NOT Direct IVP Max. dose is 60 mEq at a time Must use IV pump Monitor renal output, site Telemtery
121
Nursing Interventions of Hypokalemia
Identify pt at risk – esp. if on Digoxin Monitor ECG & BP (LETHAL DYSRRHYTHMIAS) Monitor serum K+ Pt education – diuretics & laxatives Administer K+ supplements PO or IV increase dietary K+ Monitor urine output
122
Digoxin __________ K
potentiates
123
Hyperkalemia Causes mnemonic
CARED (treatment induced)
124
When looking at fluid in our body, what are we looking to measure with?
Daily weight
125
Which potassium disorder is the most dangerous? Why?
Hyperkalemia - cardiac arrest
126
Hyperkalemia Causes
Cellular mvmt Adrenal insufficiency with Addison's disease **Renal failure** Excessive potassium intake Drugs
127
What part of the body does sodium affect the most?
brain (swelling)
128
How can cellular mvmt cause Hyperkalemia
burns, chemo the cells die and K are released
129
Addison's disease
adrenal insufficiency Na lost and K released
130
What drugs can cause Hyperkalemia?
ACE inhibitors NSAIDs Beta-blockers - increase aldosterone
131
Hyperkalemia S/S mnemonic
Muscle weakness Urine production is little/none Respiratory failure **Decrease cardiac contractibility** Early signs of **muscle twitches**/cramps **Rhythm changes** -telemetry
132
Hyperkalemia cardiac changes
Slows heart rate ECG changes **Risk for Heart Block, A-fib, or, V-fib Severe high K+** **Decreased heart contraction** strength Dilated & **flaccid** heart
133
Hyperkalemia lab value
Serum potassium > 5.3 mEq/L ECG abnormalities ABG – low pH indicating acidosis
134
Hyperkalemia treatment
**restrict diet** stop k containing meds monitor for digitalis toxicity cation exchanging resins dialysis (if absolutely needed)
135
Meds containing K
ACE inhibitors NSAIDS Beta Blockers
136
Kayexalate aka
Polystyrene sulfonate
137
Kayexalate is a
laxative binding to K and releases in the stool
138
If a patient has a digestive issue, would they be able to take Kayexalate?
no
139
Emergency med tx Hyperkalemia
Ca Gluconate - IV Hypertonic Glucose and Insulin Sodium Bicarbonate
140
Ca Gluconate - IV
**not lower K** protects the heart allowing others to work monitor ECG and telemetry
141
How long do you give Ca Gluconate?
over 3 mins
142
If the pt has bradycardia, do you stop Ca Gluconate?
Yes
143
Hypertonic Glucose and Insulin
Insulin - puts K into cells Glucose - high insulin release from the pancreas **not for diabetics**
144
What med do you give with glucose and insulin?
albuterol (shifts K into the cells) - they won't feel good and fall risk - fast hr and shakes
145
Sodium Bicarbonate moves
into the cells temporarily
146
Nursing Interventions of Hyperkalemia
Be aware of pt at risk Monitor for: -Generalized weakness & dysrhythmias -Irritability & GI symptoms -Nausea & intestinal colic ECG or lab abnormalities Prevention of hyperkalemia Educate pt: medication & diet Do **NOT draw blood above K+ infusion**
147
When should you check K after giving it?
2 hours
148
During dialysis, what happens to the BP?
BP lowers -so don't give BP lowering meds
149
Why should aldactone (potassium-sparing diuretics) not be given to renal pts?
potassium in sodium substitutes
150
Magnesium is absorbed and excreted by
GI Tract Kidneys
151
Mg Normal values
1.5-2.5 mg/dL
152
Mg critical values
<1.2 or > 4.9
153
Potassium and Magnesium are
best friends
154
Mg functions
Regulating Muscle and nerve function Blood Sugar levels Immune System
155
Mg is needed for what system
cardiac (arrhythmias)
156
Mg stimulates what hormone to regulate what
parathyroid hormone regulates Ca
157
Hypomagnesemia is often associated with
hypokalemia Low Mg makes low K resistant to treatment Keep cardiac pt at 2.0
158
Hypomagnesemia S/S
**Tight airway** --Stridor, laryngospasm, difficulty swallowing-- Hyperflexion-Muscle twitching N/V/D (increased brain activity) Irritability, insomnia, confusion, seizure Increased BP and HR
159
Hypomagnesemia Causes
Mg absorbed in the intestine* Renal loss **Chronic alcoholism (Most common)** Antibiotics GI Loss (N/V/D) Malabsorption (Crohn's, celiac disease)
160
Nursing Interventions for Mg
**Safety with swallowing** -THICK LIQUIDS, sit up and awake, tuck chin down IV Mg sulfate **(give slowly)** monitor respiratory status and reflexes
161
Food Rich in Mg
**DARK Chocolate Avocados** Milk Peas Peanut butter Oranges Nuts Bananas
162
Hypermagnesemia Causes
Antiacids **Renal Failure** **Potassium Excess**
163
Hypermagnesemia Nursing Interventions
Hemodialysis IV Calcium Gluconate Monitor Labs
164
Hypermagnesemia S/S
Heart- calm and quiet -Low and shallow Respirations -Bradycardia -Hypotension Lung -Low and shallow Respirations GI -Hypoactive Bowel Sounds Neuro -Drowsiness, lethargy MS -Weakness
165
Calcium (total) lab normal value
8.4-11
166
What percentage of Calcium is stored in bones and teeth?
99%
167
What are the 3 functions of Calcium in the body?
Bones and teeth- forms Blood - clots blood Beats - squeezing and relaxing for muscles (keep normal beats)
168
What are the 3 forms of Calcium?
Bound Ionized Complexed
169
Bounded Calcium is bounded to
proteins - albumin (less than 50%)
170
Ionized Calcium is found in
serum
171
What type of Calcium is most important?
ionized
172
What percentage of calcium is ionized?
50
173
Children have _____ level of serum Ca than elderly.
higher bc of bone growth
174
Complexed Calcium is combined with
nonprotein anions -Phosphate -Citrate -Carbonate
175
Ionized Calcium functions
activate body chemical reaction muscle contractions and relaxations promote transmission of nerve impulse cardiac contractility and automaticity formulation of prothrombin
176
Ionized Ca carries out
most of the functions
177
What relationship do albumin and Calcium have?
same low = low high = high
178
Calcium and Phosphorus relationship
inverse Low Cal = High P High Cal = Low P
179
Parathyroid Hormone does what to Calcium
**pulls** Calcium out of the bones and into blood plasma for absorption through GI and renal
180
When Calcium is low, this regulator "pulls" Ca and phosphorus from the bone.
Parathyroid Hormone
181
What are the Calcium regulators?
Parathyroid Hormone Calcitonin Phosphate Vitamin D
182
Calcitonin is secreted by the
thyroid
183
Calcitonin has a ________ relationship with PTH
ANTAGONIST
184
When Calcium is too high, this hormone is secreted from the thyroid to "keep" Ca.
Calcitonin -tones down Ca-
185
When is Calcitonin secreted?
high serum Ca
186
What is the function of Calcitonin?
**inhibits Ca reabsorption** from bone "keeps" Ca in the bone
187
Phosphate has what relationship with Calcium?
inverse high Calcium = low Phosphate
188
What does Phosphate do as a Ca regulator?
inhibits Ca reabsorption in the intestines
189
Vitamin D is necessary for what in relation to Calcium?
absorption and utilization of Ca
190
What foods are rich in Vitamin D?
mushrooms egg yolk fatty fish tuna spinach safe sun exposure
191
Hypocalcemia Causes mnemonic
LOW CAL
192
Hypocalcemia Causes
Low PTH (no regulation from surgery) Oral intake inadequate (alcoholism and bulimia) Wound drainage (low absorption) **Celiac, Crohn's (malabsorption) and corticosteroids (increase the bone breakdown and body unable to absorb)** Acute pancreatitis (low PTH secretion) Low Vitamin D (no absorption)
193
High doses of steroids cause
osteoporosis
194
Hypocalcemia S/S mnemonic
CRAMPS
195
Hypocalcemia S/S
**Confusion** Reflexes hyperactive Arrhythmias (cardiac floor) Muscle spasms (**tetany**, seizures) - mouth and fingertips **Positive Trousseau's Signs of Chvosteks (facial)**
196
Trousseau's
**hand spasm when BP is taken** due to the low blood supply and **pressure on nerve** -increase in systolic BP
197
Chvostek's
**facial nerve spasm** tap facial nerve anterior to ear lobe below zygomatic process
198
Hypocalcemia - Cardiac effects
**dysrhythmias torsades de pointe** decrease cardiac contractibility decrease sensitivity to Digoxin
199
Torsades de pointe
ventricular tachycardia by hypocalcemia arrhythmias
200
Low serum calcium (hypocalcemia) = _______ albumin
low
201
What hormone levels can affect Ca?
Parathyroid Hormone
202
What levels should be obtained along with Calcium?
Mg Phosphorus
203
What is the purpose of IV Therapy?
Provide -H2O -Electrolyte -Nutrients Replace deficits Administer meds and blood TPN, dysphagia Emergency situations
204
TPN can only go through
Central line
205
Advantage of IV Therapy
emergency access administration route when PO is not available continuous fluids control over rate
206
Disadvantages of IV Therapy
damage fluid overload overdose **infections** immobility incompatibility adverse reactions electrolyte imbalance
207
If a pt has an allergic reaction to an IV medication, what should you do?
Stop infusion Call infusion Get help
208
When assessing an IV, what do you do?
check patency, wear gloves signs of infection check rate and med, allergies and compatibility
209
What are the signs of an infection?
fever tenderness redness respirations increase swelling
210
Hypovolemia AKA
dehydration deficient in fluid
211
When do you change an IV?
48 hours PRN
212
Hypovolemia leads to
hypovolemic shock
213
Hypovolemia Causes
loss of fluid from anywhere -Thoracentesis/Paracentesis -**hemorrhage/bleeding** -NG Tube -Trauma -**n/v** -**severe dehydration** -conditions causing polyuria -**diuretics** -3rd spacing (**burns** and ascites)
214
Hypovolemia via polyuria diseases
Diabetes Diabetes Insipidus Diuretics
215
3rd Spacing is when
fluid shifts from intravascular to the interstitial
216
Hypovolemia S/S
**DECREASE WT** increase hr **(thready)** **Low BP, urine output, and CVP** dark concentrated urine increase respiration rate Tenting skin Thirst and dry mouth** flat neck veins
217
What is a severe symptom of hypovolemia?
HR increases by compensating
218
When remembering BP and Volemia (hypo and hyper), what do you need to know?
Low volume = low pressure High volume = High pressure
219
Hypovolemia Labs
**concentrated** = **higher numbers** of serum osmolality, specific gravity, hematocrit, **serum sodium**, and BUN
220
Hypovolemia Treatment
Replace fluid (PO or IV) - Monitor for Fluid overload Orthostatic hypotension safety precautions - rise slowly when standing Daily wt and I&Os
221
Hypervolemia AKA
OVERHYDRATION excess
222
Hypervolemia Causes
Heart failure kidney dysfunction cirrhosis increase sodium intake
223
Hypervolemia is more common in
elderly pts
224
Hypervolemia S/S
**daily wt gain** increase HR **(BOUNDING)** **increase BP**, CVP, URINE **(polyuria)** **wet lung sounds** edema distended neck veins **JVD**
225
When should a pt be concerned with gaining weight and contact a doctor?
increase of 2 lbs a day 5 lbs a week
226
Hypervolemia Labs
diluted **low values**
227
Hypervolemia Tx
low sodium diet Daily I&O and Wt Monitor V/S and assess respiratory rate Diuretics High-Semi-Fowler's position (relieve lungs)
228
What are the different crystalloids in IV Solutions?
isotonic hypotonic hypertonic
229
What 3 things determine the type of IV solution given to the pt?
condition diagnosis lab values
230
Aquaporin channels
allow water molecules to pass through cell membranes without using energy
231
Diffusion
movement of particles from **higher to lower concentration**
232
Hypertonic
higher concentration of salt water rushes out of the cell **cell shrinks - plasmolysis**
233
Hypotonic
very watery water goes into the cell and attaches to NaCl **cell swells and possible cytolysis**
234
Isotonic
**stays the same** dynamic equilibrium
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The osmolality of the blood
the concentration of all chemical particles found in the **intravascular/fluid part of the blood**
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Osmolality **primarily** reflects concentration of:
sodium BUN glucose
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What relationship does sodium have with osmolality?
direct (low = low)
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What is the normal value of osmolality?
280-300
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Factors Increasing Osmolality
dehydration (concentration of Na) free water loss DI (polyuria) Hypernatremia Hyperglycemia Stroke from a head injury Renal Tubular necrosis (kidney's dead)
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Factors Decreasing Osmolality
fluid vol excess SIADH Renal failure Hyponatremia Overhydration
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Isotonic Solutions are given to
replace fluid loss
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Isotonic Solutions osmolality
similar to ECF 280-300
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T/F: Isotonic Solutions DO cause RBCs to shrink or swell.
False, they do not.
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Isotonic Solutions are given through IV where does it go?
stays in the intravascular system
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Isotonic Solutions
D5W (changes to hypotonic) NS LR
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D5W contains
water and glucose
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How does D5W change from isotonic to hypotonic?
isotonic outside the body but once infused dextrose is rapidly metabolized, then the water becomes hypotonic
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What isotonic solution do we need to use caution with for diabetics, hypernatremia, and head trauma pts?
D5W cause hyperglycemia bc dextrose cause hypotonic after sugar is used and cause cells to swell (cerebral edema)
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Can you reverse cerebral edema?
no
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D5W is primarily used to treat
hypernatremia BUT use it with caution
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If too much D5W goes into the cells, then what is your first sign of swelling?
decrease LOC
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NS is used to correct
correct extracellular volume deficit - hypovolemia - resuscitative efforts - shock -metabolic alkalosis - hypercalcemia - hyponatremia
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Does NS have calories?
no
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What is the only solution that can be given with NS?
blood
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NS replaces large amounts of sodium ___________
losses
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NS is not used/cautioned for what pts?
CHF Pulmonary edema renal impairment trauma
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If at-risk pts, start having crackles in the lungs, dyspnea, and anxiety, then what should the nurse do?
stop infusion sit up O2 dr notification - let pt know and try to decrease anxiety possible diuretics given
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LR contains what electrolytes?
potassium calcium sodium chloride
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LR is used to correct
dehydration sodium loss GI loss (vomiting, diarrhea)
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LR should be used with caution with what pts
CHF Renal insufficiency edema sodium retention hyperkalemia
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Hypotonic Solutions osmolairty
less than 280 -depletes ECF
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Hypotonic _________ ECF
DILUTES lowering serum osmolality
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Hypotonic solutions are used for
hypernatremia (not for fluid replacement)
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If hypotonic solutions are given for too long,
cells swell to a cerebral edema
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Hypotonic solutions _______ BP
lower
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Hypotonic solutions types
lower amounts or fractions
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Hypotonic fluid shifts such as
intravascular fluid depletion low BP cerebral edema
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What patients are at risk of worsening hypotension if given hypotonic fluid? Select all that apply. ICP CVA Head trauma Burns Malnutrition Liver disease
All of the above. ICP CVA Head trauma Burns Malnutrition Liver disease
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Hypertonic solutions osmolality
greater than 300 - water to move out of the cells
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Hypertonic solutions are given to
decrease risk of edema stabilize BP regulate urine output -repair electrolytes and acid/base imbalances -TPN
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Hypertonic solutions are usually given through a
Central line
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Hypertonic solutions are used to with caution in patients with
diabetes impaired heart and kidney function
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What should be closely monitored for hypertonic solutions?
circulatory overload
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Hypertonic solution types are
high numbers
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Colloids are
large molecules not dissolved and can't pass through membrane - **volume expansion**
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Primary reason for colloids
pull fluid into the bloodstream
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What is given after dialysis to stabilize BP?
albumin
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What is the most common colloid given?
albumin
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Dextran
plasma vol expander
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Hetastarch
synthetic vol expander
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Mannitol
alcohol sugar (usually neuro)
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Albumin pulls what into the blood vessels
salt and water - to not leak out fluid from intravascular to maintain BP
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If you have a pt who came back from a Paracentesis, which they drained 3L of fluid from, what is their expected BP going to be? What would the nurse expect to be given or prescribed to the pt?
low -Albumin (to stabilize BP)
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Albumin carries what throughout the body
hormones vitamins enzymes
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What should be monitored when giving patients an infusion of colloids?
increase in BP Dyspnea bounding pulse fluid overload (JVD, high BP, resp distress) anaphylaxis I&O, wt, v/s
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What electrolytes need to be monitored on albumin?
potassium sodium
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Phlebitis
inflammation of vein
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Causes of phlebitis
poor asepsis high osmolality infusion improperly diluted meds incorrect gauge **too rapid infusion**
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S/S of phlebitis and thrombophlebitis
tenderness redness heat edema
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Prevention of phlebitis and thrombophlebitis
rotate site dilute properly slow infusion aseptic
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Intervention of phlebitis and thrombophlebitis
stop infusion remove apply warm compress
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How long can an IV stay in place
48 hours PRN
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Thrombophlebitis
formation of clots and inflammation in the vein - **occurs after phlebitis**
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Causes of thrombophlebitis
injury to vein infection chemical irritation prolonged use of the same vein
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Infection
pathogen in surrounding tissue of IV site
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Causes of infection
lack of aseptic loose or contaminated dressing prolonged use of vein
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S/S of infection
redness tenderness swelling edema
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Air embolism
air entering the vein becomes trapped in the blood as it flows - rate of entry very important
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Causes of air embolism
solution runs dry improper priming loose connections poor technique in dressing, tubing, and removal of central lines
300
How do you remove Central lines?
left reverse Trendelenburg hold for 5 mins
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S/S of air embolism
dyspnea, unequal breath sounds cyanosis hypotension weak, rapid pulse LOC chest, shoulder, low back pain shock death
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Air embolism Tx
stop infusion and clamp call for help left Trendelenburg O2 V/S emergency equipment ready
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Speed shock
systemic reaction when med is rapidly introduced into circulation -caused by too rapid infusion
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S/S of speed shock
dizzy face flushing HA hypotension chest tightness irregular pulse shock progress
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Prevention of speed shock
correct rate pump close monitor
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What fluid shifting is abnormal?
3rd spacing
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K lower than 2.7 may result in what happens to the heart
V-fib cardiac arrest
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Hypocalcemia Tx
10% Ca Gluconate (severe symptoms) Ca-Chloride **(never IM)** Oral Ca (antacids and dairy and vit D)
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With acute symptomatic hypocalcemia, what should the nurse do?
EMERGENCY -requires prompt admin. of IV Calcium
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With IV Calcium, what needs to be watched closely and why?
IV site Infiltration - cause necrosis and sloughing
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Rapid infusion of Calcium can cause what complications?
bradycardia leading to cardiac arrest
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Calcium does what to the BP of a patient and what risk might they be placed on?
Posterior hypotension - Fall risk - stay in bed
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Nursing Interventions of Hypocalcemia? At risk?
- At risk = parathyroid surgery/injury seizure precautions if severe low **monitor airway and telemetry** Educate- Calcium rich diet
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HYPERcalcemia Causes mnemonic
HIGHCAL
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HYPERcalcemia Causes
**Hyperparathyroidism** and cancer Increased Ca intake Glucocorticoid usage (increase CA excretion = increase PTH and increase bone reabsorption) Hyperthyroidism Calcium excretion** w/ thiazide diuretics** (potentiates and raises PTH) Adrenal insufficiency (Addison's) Lithium (affects parathyroid) -**prolonged immobilization**
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HYPERcalcemia S/S mnemonic
WEAAAK
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HYPERcalcemia S/S
**Weakness** of muscles EKG changes (slows heart rate) **Absent reflexes**, mind (disoriented) **Abdominal distension** (constipation) **Kidney stones**
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HYPERcalcemia - Cardiac
**stimulates contractibility and lowers heart rate** Arrthymias lead to cardiac arrest potentiate digoxin toxicity
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Digoxin and Calcium do what with each other?
potentiate - worry about K in the blood with these
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Digoxin toxicity
confused vision changes irregular hr loss of appetite
321
Hypercalcemia Labs
greater than 11 dysrrthymias PTH high Xray osteoporosis Urine
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Hypercalcemia Tx
treat underlying cause Dilute serum Ca with **NS** **Loop Diuretics - Lasix** IV Phosphate - inverse relations Calcitonin Glucocorticoids - inhibit reabsorb Hemodialysis
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What drug is safe to give HYpercalcemia pts with heart or renal issues too?
Calcitronin
324
Hypercalcemia Nursing Interventions -at risk
- AT risk = **Increase activity and fluids** lower Ca intake **Confusion safety** Monitor EKG, I&O, breath sounds **Dig toxicity** **Prevent kidney stones**
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Phosphorus lab normal
2.5-4.5
326
High Calcium =
low phosphate -cardiac and neuromuscular problems
327
Phosphorus is mainly found in the
teeth and bones like Ca
328
Functions of Phosphorus
bone and teeth form repair cell tissues and energy nervous system muscle function
329
Phosphorus is regulated by
parathyroid and calcitriol
330
Phosphorus is high in foods
dairy meats and beans
331
Hypophosphatemia Causes
**Malnutrition/starvation - most common** Increased Phosphorous excretion Hyperparathyroidism (Calcium increases: Phos drops) Malignancy Diuretics/Diarrhea Use of magnesium/aluminum antacids (Increases Ca, depletes phos)
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Hypophosphatemia S/S
SAME AS HYPERCALCEMIA Cardio: Decreased BP/HR** GI: hypoactive Bowel sounds** GU: Kidney stones** NEURO: Altered LOC** MUSC: Severe muscle weakness** Bone pain/fractures
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Hypophosphatemia Interventions
replace Phosphorus IV/PO **give slow** **PO with Vitamin D** **Fracture precautions**
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Hyperphosphatemia Causes
Increased Phosphorus intake **Overuse of laxatives**-elderly Renal insufficiency= Decreased excretion Hyperparathyroidism Hypocalcemia
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Hyperphosphatemia
Diarrhea Hyperactive bowel sounds **Positive Trousseau’s/Chvostek’s** Painful muscle spasms Hyperactive Deep tendon reflexes Irritable skeletal muscles –twitches, **tetany**, seizures Osteoporosis
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Hyperphosphatemia Interventions
Replace Calcium (IV/PO) **IV Calcium gluconate 10% (Monitor BP, HR)** *Vitamin D* when giving PO Aluminum Hydroxide (Tums)* Initiate seizure precautions Move pt carefully Educate on calcium-rich foods dairy
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Thyroid inflammation is known as a
goiter
338
SIADH
retain too much water leads to hyponatremia
339
DI
BODY MAKES TOO MUCH URINE (20qts/day) -polyuria hypernatremia
340
Potassium can go through ________ __ but you prefer a central line
peripheral IV (slowly - 10 mEq)