Thyroid Flashcards

1
Q

What is the thyroid hormone feedback loop?

A

Ant. Pituitary stimulates thyroid hormone production & release
If blood levels of TH are low then the hypothalamus release TRH
TRH causes the Ant Pituitary to release TSH
TSH stimulates the thyroid to release TH
High TH levels inhibit the secretion of TRH & TSH

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2
Q

If blood levels of TH are low then the

A

hypothalamus releases TRH

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3
Q

Hormone Orders IF LOW LEVELS

A

Thyroid releasing hormone
Thyroid-stimulating hormone
T3 and T4

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4
Q

TRH causes

A

Anterior pituitary to release TSH

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5
Q

TSH releases what

A

T3 and T4 from thyroid

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6
Q

High T3 and T4 levels inhibit the secretion

A

TRH
TSH

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7
Q

TRH

A

Thyroid releasing hormone

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8
Q

TSH

A

thyroid-stimulating hormone

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9
Q

Thyroid assessment

A

physical
Lab work (serum TSH, T3, T4, and free T4)
Ultrasound with bx (remove portion)
Thyroid scan
RAI uptake

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10
Q

If questioning hyperthyroidism/enlarged thyroid,

A

listen for bruit and audible vibration

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11
Q

Is the thyroid normally palpable?

A

no, only when enlarged or hyperthyroidism

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12
Q

How do you assess the thyroid?

A

stand posterior to pt
warn and place hands around the neck
pt swallows - brings it forward to feel for nodules in thyroid

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13
Q

When should you not palpate the thyroid?

A

pt has Thyroiditis
esp if notice visibly enlarged gland bc palpation triggers release of thyroid hormones

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14
Q

RAI uptake

A

Radioactive Iodine uptake test
- if low iodine in thyroid with test hypoactive visa versa

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15
Q

RAI uptake contraindications

A

allergies to shellfish and iodine
Meds need to be withheld

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16
Q

Goiter

A

abnormal enlargement of the thyroid gland

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17
Q

Goiter occurs with

A

Hyperthyroidism (too much)
hypothyroidism (too little)
Euthyroidism (correct amount)

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18
Q

T/F: The presence of a goiter does mean the thyroid gland is malfunctioning.

A

False

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19
Q

Goiter pts c/o

A

inability to swallow
shirt collars too small

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20
Q

TSH normal

A

2-10

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21
Q

T4 normal

A

4-12

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22
Q

T3 normal

A

70-205

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23
Q

Hypothyroidism lab values
TSH
T3
T4

A

TSH high
T3 low
T4 low

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24
Q

Hyperthyroidism lab values
TSH
T3
T4

A

TSH LOW
T3 HIGH
T4 HIGH

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25
TSH is used when monitoring
thyroid replacement therapy
26
TSH STIMULATES
T3 and T4
27
T3
accurate meaure of hyperthyroidism after admin of iodine
28
Free T4
measures the free unbound thyroxine levels of the bloodstream
29
Hyperthyroidism
excess of thyroid hormone
30
Hyperthyroidism results in
Increase BMR, CV, GI & neuromuscular function Affects metabolism of fats, carbs & proteins **Wt loss & heat intolerance**
31
Hyperthyroidism caused by
Autoimmune rxn **(Graves’ disease)** Excess of dose of thyroid replacement Thyroiditis Tumor
32
Thyrotoxicosis
thyroid storm
33
Assessment of Hyperthyroidism
**High Temp, Pulse, Resp. and BP** -clubbing, localized edema Nervous, tremors wt loss, hunger N/V/D **breast enlargement** weakness, fatigue **intolerance to heat** **Grave's disease**
34
S/S of hyperthyroidism is related to
directly increases metabolism and tissue sensitivity to stimulation by the sympathetic nervous system
35
Graves' disease s/s
Goiter **Bulging eyes raised red rash not painful**
36
Hyperthyroidism is prone to
comorbidities * irregular heartbeats chest pain cognition low excess fatigue**
37
Hyperthyroidism Mgmt
lifelong antithyroid med **Iodine 131 Thyroidectomy** infertility specialist
38
Nursing problems with Hyperthyroidism
knowledge deficit insufficient nutrition (give them frequent small meals with more protein and carbs) altered sleep patterns altered body image due to goiter and eye bulging low CO or endurance vision changes (dry and shape)
39
Exophthalmos
bulging eyes
40
Hyperthyroidism pts have a
high active can't sit still Revved up constantly but tired from overexertion
41
Hyperthyroid pts should avoid
spicy high fiber foods caffeine **decongestants and diet pills**
42
Hyperthyroid pts need to monitor weight loss if and be notified if they
more than 10% of body wt
43
Hyperthyroidism education
meds **wt and nutrition increased** balance activity and rest (fatigue) lifestyle changes **Eye exams with drops and protection** due to bulging HOB elevated
44
Hyperthyroid meds
Methimazole/propylthiouracil (PTU)
45
PTU goal
inhibits thyroid hormone synthesis
46
PTU adverse effects
**agranulocytosis hypothyroidism
47
PTU contraindications
allergy to thioamides impaired liver **Pregnancy leads to fetal harm**
48
PTU care
signs of hypothyroidism and hyperthyroidism Lab work WNL (PT, INR, CBC, Liver, and Ts) VS and wt
49
Do not stop PTU abruptly or
risk of severe HYPERTHYROIDISM - fever, sore throat, unusual bleeding
50
PTU should be taken
same time of day with food
51
Radioactive Iodine 131 goal
destroy thryoid cells at high doses
52
Radioactive Iodine 131 adverse effects
radiation sickness bone marrow suppression hypothyroid
53
Radioactive Iodine 131 contraindications
pregnancy young children
54
Radioactive Iodine 131 dosage
4-10 PO
55
Radioactive Iodine 131 TEACHING
baseline and monitor CBC **private toilet and flush twice Bathe daily and frequent handwashing disposable utensils sleep alone and avoid prolonged intimate contact for 3-4 days separate linens limit visitors and private room needed**
56
Radioactive Iodine 131 can jar the thyroid when the pt does this so avoid
avoid coughing and expectoration
57
Strong Iodine solution - NONradioactve goals
reduces iodine uptake, inhibits hormone production blocks release of T3 and T4
58
Strong Iodine solution - NONradioactve ADVERSE EFFECTS
iodism
59
Strong Iodine solution - NONradioactve dosage
2-6 drops TID for 10 days
60
Iodism
corrosive and toxicity metallic taste with irritation sore gums, teeth, ulcers, swelling in the upper throat
61
Strong Iodine solution - NONradioactve mixed with
juice
62
Strong Iodine solution - NONradioactve mgmt
signs of iodism VS , WT gain, I&O under and overdosing
63
Strong Iodine solution - NONradioactve TEACHING
Dilute medication in juice to help with taste Avoid foods high in iodine (ionized salt) Take medication same time each day Increase fluid intake
64
Hyperthyroidism in older adults
2x wt loss from anorexia as well apathy lassitude depression confusion dysrhythmia to heart failure exophthalmos less common
65
Thyrotoxic Crisis aka
Thyroid storm
66
Causes of thyroid storm
severe infection/stress manipulation of thyroid gland
67
Thyroid storm assessment
**101.3+ temp** **increase HR 130+, HTN** agitation, confusion, seizure exaggerated s/s of hyperthyroidism
68
Dx testing of thyroid storm
plus cardiac testing
69
Tx of Thyroid Crisis
Stabilize Cardiac **beta blockers** O2 Replace fluids and electrolytes - **D5NS or D5LR** When stabile = Antithyroid meds **PTU, corticosteroids, lithium or iodinated contrast** Calm environment - cold, dark, limits visits, no kids
70
Thyroiditis
inflammation of thyroid acute, subacute, chronic
71
Acute Thyroiditis is caused by
bacteria fungal parasite
72
Acute Thyroiditis s/s
**painful** swelling dysphagia dysphonia s/s of hyperthyroidism
73
Tx of Acute Thyroiditis
antibiotics fluid replacement
74
Acute Thyroiditis function
returns after tx
75
Subacute thyroiditis caused by
granulomatous - viral
76
Subacute Thyroiditis s/s
low fever fatigue swelling pain
77
Subacute Thyroiditis s/s Phases
Phase 1: hyperthyroid (1-3 months) Phase 2: hypothyroid (9-12 months)
78
Subacute Thyroiditis Tx
NSAIDs Beta-blockers in Phase 1 (heart beats) steroids for swelling
79
Subacute Thyroiditis function
normal after 12-18 months
80
Subacute Thyroiditis Miantain good
birth control because babies pop out more
81
Chronic Thyroiditis s/s
lymphocytic - autoimmune
82
Chronic Thyroiditis aka
Hashimoto's disease
83
Chronic Thyroiditis s/s
**painless** hypothyroid s/s
84
Chronic Thyroiditis Tx
thyroid replacement
85
Chronic Thyroiditis function
never returns slowly
86
Thyroidectomy
tx of choice for thyroid CA and goiters if airway problems
87
CA surgery may include
modified or radical neck dissection
88
Radioactive Iodine in Thyroid CA
minimize metastasis shrink thyroid
89
Thyroidectomy Pre-op teachings
nutrition soft foods (soups, mash, Jello) avoid caffeine and stimulants
90
Thyroidectomy post-op care
head & neck support (pillows, no rocking forward with head to strain the neck, use arms to side for pushing) HOB for swelling feeding tubes incision painful to swallow for 24 hours Incision & **airway**: bleeding (anterior and side collarbones), airway obstruction thyroid hormone: depends on the amount left, if total lifelong thyroid replacement, weaning can occur but usually very slow
91
Thyroidectomy Post-Op Care BOW TIE
Bleeding Open airway: HOB 30, avoid hyperextending Whisper: laryngeal nerve next to the thyroid to reassess with a small voice Trache set depends Incision Emergency: muscle twitching
92
Pain meds for thyroidectomy
before eating to ease swallowing of foods
93
Why do you need to watch for muscle twitching after thyroidectomy?
parathyroid triggered and can go into hypocalcemia
94
Hypothyroidism
Insufficient T3 & T4 leads to  BMR, *low heat production*
95
Hypothyroidism Causes
tx of hyperthyroidism - PTU antibody destruction of thyroid iodine deficiency
96
Hypo/Hyper Thyroidism analogy
Hypo - tortoise Hyper - energizer bunny
97
Hypothyroidism Assessment LABS
high TSH and lipids low T4 and T3
98
Hypothyroidism VS
low BMR, Temp, Pulse, BP
99
Hypothyroidism ASSESSMENTS
wt gain dry skin and hair constipation **lethargic and fatigued** intolerance to cold **mixed edema**
100
Hypothyroidism late s/s
**mixed edema** subnormal temp bradycardia wt gain low LOC thickened skin cardiac complications
101
Hypothyroidism mgmt
thyroid replacement (T3 and T4)
102
Hypothyroidism NURSING Problems
Knowledge deficit: don't know how or when to meds low CO, endurance, & temperature Excess nutrition: fatter Constipation Skin integrity: dry (need hydration) Body image: fat and skin integrity
103
Hypothyroidism anaesthesiology and sedation meds need to be
minimal dose -increase risk of oversedation and respiratory compensation
104
Hypothyroidism meds to caution
sedatives hypnotics narctoics
105
Hypothyroid meds
levothyroxine (Synthroid)
106
levothyroxine (Synthroid) goal
Synthetic T4 – produces various physiologic effects, including increasing metabolism
107
levothyroxine (Synthroid) adverse effects
thyrotoxicosis Extremes; jitters, grumpy, thyroid storm wt loss too much too quickly
108
levothyroxine (Synthroid) is dosed in
micrograms
109
levothyroxine (Synthroid) contraindications
acute MI CVD Thyroid storm
110
levothyroxine (Synthroid) nursing care
Assess vital signs, BP, weight, history of; weight change, diet, energy level, mood, temperature response **Monitor thyroid function test results & glucose levels** Give dose in **morning before breakfast** Teach symptoms of thyrotoxicosis
111
levothyroxine (Synthroid) teaching
Daily lifelong if not mixed edema report any signs of chest pain, nervousness, tremors, sleeplessness, heat intolerance, & excessive sweating Do not discontinue medication suddenly
112
What is the major warning sign for med attention in thyroid storm
chest pain
113
If Synthroid dose is too low
bradycardia lethargy constipation excessive fatigue and sleeping
114
If Synthroid dose is too high
irritability palpations tachycardia diarrhea tremors insomnia
115
Hypothyroid clients need
follow up contact if unplanned wt loss/gain of 5 lbs in a week avoid sedatives take in the morning
116
Mixed edema
severe hypothyroidism
117
Mixed edema causes
sudden d/c thyroid replacement acute illness, trauma
118
Mixed edema assessment
s/s of hypothyroid edema non pitting low T4, Na, glucose High TSH possible CV collapse and coma HR less than 50 tongue swells
119
Myxedema Management
Replace T4 Treat precipitating factors Respiratory & CV support** Increase body temperature Maintain fluid, electrolytes, & acid-base HIGH flow O2warming blanket Vasopressors
120
The nurse is completing a health assessment of a patient with suspected hyperthyroidism. What should the nurse assess the client for? Anorexia Tachycardia Weight gain Cold skin
Tachycardia
121
The nurse is evaluating a patient who is taking PTU for hyperthyroidism. Which patient statement indicates the drug is effective? I have excess energy. I can sleep at night. I have lost weight since taking this medication. I perspire throughout the day w/o exertion.
I can sleep at night.
122
Following a subtotal thyroidectomy, a patient begins to have tingling in the fingers and toes. What should the nurse do first? Encourage the patient to flex & extend fingers & toes Notify the healthcare provider Assess for thrombophlebitis Ask the client to speak
Notify the healthcare provider hypocalcemia factor