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HEMATOLOGY & ONCOLOGY > FONDAPARINUX > Flashcards

FONDAPARINUX Flashcards

1
Q

Mechanism

A

Combines with antithrombin
Inhibits Xa

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2
Q

Dosing

A

DVT PPX: 2.5 mg subcut daily
NSTEMI: 2.5 mg subcut daily
STEMI: 2.5 mg IV day 1 THEN 2.5 mg subcut daily up to 8 days or until PCI complete

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3
Q

Monitoring

A

Not required
If needed, anti-Xa assay

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4
Q

Clearance

A

Renal

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5
Q

Half Life

A

17-21 hours
Renally cleared, half life prolonged in renal failure

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6
Q

Elective reversal

A

Stop prophylactic 24 hours prior
Stop therapeutic 1-2 days prior

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7
Q

Antidote

A

None

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HEMATOLOGY & ONCOLOGY (15 decks)

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