Frontotemporal dementia Flashcards
1
Q
what is the definition of FTD?
A
The FTD spectrum comprises a heterogeneous group of conditions that are heritable in some cases.
Frontotemporal dementia manifests primarily as disruption in personality and social conduct, or as a primary language disorder
2
Q
what is the epidemiology of FTD?
A
2nd cost common EARLY PRESENTING dementia (<65 yrs)
Typically appears 45-65
3
Q
what are the genes that may be mutated in FTD?
A
Mutations in MAPT gene
Mutations in GRN gene
Mutations in C9orf72 gene
4
Q
what are the key presentations for FTD?
A
Personality changes Language disorders Parkinsonism MND Disorientation Self neglect
5
Q
how is FTD diagnosed?
A
Clinical diagnosis
Identify gene mutation
6
Q
how is FTD treated?
A
Supportive care
Benzodiazepine for irritability
