function of the nephron Flashcards

(41 cards)

1
Q

where does ulterfiltration occour

A

the glomerulas

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2
Q

what is the artriole that takes blood into the glomerulas called

A

the efferent artriole

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3
Q

what is the glomerulas comprised of

A

capillaries

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4
Q

what are the glomerular capillaries made up of

A

epithelial cells with pores between them

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5
Q

what is formed in the glomerulas that allows ulterfiltration to occour

A

hydrostatic pressure is formed

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6
Q

how is this hydrostatic presure formed

A

the differance in size between the afferent artriole wich has a smaller diameter compared to the efferent atriole.

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7
Q

what does this hydrostatic pressure do

A

forces small water glucose and mineral ions into bomans capsual forming glomerular filtrate

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8
Q

what is the water, glucose and mineral ions known as when pushed out of pores

A

glomerular filtrate

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9
Q

what remains in the blood stream

A

blood cells and protiens

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10
Q

why do they reamain in the blood stream

A

they are too large

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11
Q

what do these large cells leave via

A

the efferent atriole

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12
Q

what occours after uterfiltration

A

selective reabsorbtion

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13
Q

where does selective reabsorbtion happen

A

the proximal convoluted tubual

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14
Q

what absorbs glucose and aa into the blood

A

epithelial cells in the lining of the pct

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15
Q

what makes the epithelial cells suited for their absorbtion

A

microvilli - provide large SA
mitochondria - provide lots of energy for active transport and co transport

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16
Q

what is the mitochondria in the epithelia cells used for

A

active and co - transport

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17
Q

describe the process of reabsorbtion

A

sodium ions actively transported into the blood lowering the sodium con in epithelial cells.
sodium ions diffuse down con-gradient into cells via facilitated diffusion with the use of a carrier protein.
travels from lumen of pct into epithelial cells surrounding it.
carrier protiens contransport molcules such as glucose and aa into epithelial cells
co-transported molecules diffuse dwn a conc gradient into the blood.

18
Q

how do glucose molecules move into epethillial cells

A

via co-traqnsport with sodium ions through a carrier protien

19
Q

how do sodium ions move into the epithellial cell

A

facillitated diffusion

20
Q

how are the co-transported molecules transported into the blood stream

A

via diffusion down a conc gradient wich is alwas maintained as blood constantly moves away

21
Q

how is ultra filtration resisted out of the glomerulas

A

cappillary epithelial cells
epithelila cells of renal capsual

22
Q

what is esential for selective reabsorbtion in terms of establishing conditions

A

maintaining the gradient of sodium ions

23
Q

what miantains the gradient of sodium ions

A

loop of henle

24
Q

what are the two regions in the loop of henle

A

descending limb
ascending limb

25
what is the differance between the ascending and descending loop
descending lopp is permiable to water ascending loop has thicker walls so is not
26
why is the ascending loop imperable to water
because it has thicker walls
27
what happens in the ascending loop of henely
sodium ions actively transported out into intertitial space
28
what does the active transport of na ions out of ascending loop mena
lowers water potential outside
29
due to the low water potential outside loop of henle what happens
water moves out of descending loop into the surrounding blood capillaries wich is hopw water enters the blood
30
where else does water go when it moves out os descending limb
interstitial space
31
what is the concentration at the bottom of the loop of henle
high conc of na+ ions becuase most water has moved out via desceding loop, this means that na+ ions can easily diffuse out into interstitial space
32
why is their a high conc of na ions at the bottom of loop of henle
because most water has moved out via descending loop
33
what does this high conc of sodium ions mean
sodium can easily diffuses out into interstitial space
34
what changes that makes na+ ions move out of ascending loop via activetransport
as their is a large amount of na+ ions at the bottom of the loop of henle they can easliy move out via diffusion but as more move out the conc of na+ ions left is lower so they have to move out via active transport
35
what does the movment of the na+ ions out of the ascending loop result in
a filtrate with a high water potential
36
why does it result in a filtrate with a high water potential
as water is unable to move out in the ascending loop due to it's thick walls
37
after movement out of loop of henle where does filtrate go
collecting duct
38
what happens at the collecting duct
water moves out via osmosis into blood capillaries
39
what does the osmosis of water out of collecting duct mean
lowered water potential
40
what continues to allow osmosis in collecting duct even when their is a low water potential in collecting duct
water potential of filtrate is lower but so is water potential of interstilita space due to the constant movement of blood taking water away so water keeps moving out of collecting duct. this is an example of the counter current model
41
why is the water potential of interstial space still lower than that in collecting duct
due to constant movement of water away bu the blood capillaries