Flashcards in Fungal and parasitic infections of the CNS Deck (26):
What are the five fungi that have potential to cause systemic infections?
1. Histoplasma 2. Blastomyces 3. Paracoccidioides 4. Coccidioides 5. Cryptococcus
What is the leading cause of fungal meningitis?
Which fungus is yeast in both environment and tissues?
Which fungus is dimorphic?
Which fungus has a spherule as part of its development?
Coccidiodes immitis - spherule in tissues
What is the treatment for coccidial meningitis?
What is the treatment for cryptococcal meningitis?
6-10 weeks with Amphotericin B and 5-fluorocytosine / fluconazole
What are the zygomycetes?
Rhizopus, absidia, mucor
What is the morphology of the zygomycetes?
Broad, aseptate hyphae and sporangia bearing sporangiophores
Which fungal infection is seen primarily in diabetic patients?
Rhinocerebral zygomycosis is seen mostly in what population?
Entamoeba histolytica is associated with what condition?
Trypanosoma brucei is associated with what condition?
Plasmodium falciparum is associated with what condition?
What are the three free-living amoeba?
Acanthamoeba, naegleria, balamuthia
What causes primary amebic meningoencephalitis?
Naegleria fowleri is typically seen in what environments?
1. Mostly in southern states 2. Hot tubs 3. Neti pots
What causes granulomatous amoebic encephalitis?
Acanthamoeba and balamuthia
Acanthamoeba keratitis is mostly seen in what type of condition?
Chronic infection of cornea - associated with contact lens use
What is the lifecycle of toxoplasma gondii?
1. Sporozoan parasite that reproduces in gut of cats 2. Oocysts contaminate food
What indicates acute infection during prenatal toxoplasma gondii testing?
IgM or rising IgG titer
Ingestion of encysted taenia solium larvae results in what condition?
Ingestion of embryonated taenia solium eggs results in what condition?
Neurocysticercosis is a complication from what disease?
Taenia solium (pork tapeworm) extra-intestinal infection
What is visceral larval migrans?
Infection of man by ascarid worms which normally infect dogs and cats