Fungus

Question 1

Mycology:

• 4 unique things about fungi?
• Systemic mycosis in cold? Heat?
• Treatment for local?
• Treatment for systemic?
• Person to person transmission?

Answer 1

• Chitin, cellulose, ergosterol, some poly capsule
• Mold; yeast unicellulr fission/budding sex
• Fluconaole
• Amph B
• None

Question 2

Histoplasmosis:

• Other name? Location? Live on what? Why?
• Histo hides where?
• Clinical? (3)
• Aids patients get?
• Size?

Answer 2

• Spelunkers dz; ohio river; bat poop; nitrogen
• Macs
• Pneumonia, oropharyngeal ulcer; adrenal glands
• Splenic/ liver calc.
• Small

Question 3

Blastomycosis:

• Blasto buds how?
• Thick what?
• Clinical? (3)
• Size?
• Location?
• Types of nodule?

Answer 3

• Broadly
• walled
• Inflamm. lung dz; bone skin
• same as RBC
• Ohio river
• Granulomatous

Question 4

Coccidiomycosis:

• Instead of yeast?
• Clinical? (3)
• Location?
• Spherule size? Filled with?
• Arthrospores shape?

Answer 4

• Spherule
• Pneumonia, meningitis, erythema nodosum, arthralgias
• SE US
• Much bigger than RBC with endospores
• Alternating barrel

Question 5

Paracoccidiomycosis:

• Common where?
• Clinical?

Answer 5

• Brazil

- Mucocutaneous ulcer

Question 6

Tinea versicolor:

• Caused by?
• Food?
• Clinical?
• Histology appearance?
• Treatment?

Answer 6

• Mallasezia furfur
• lipids
• Hypo/hyperpigmented
• Spaghetti with meatballs
• Miconazole

Question 7

• Dermatophytes:
• 3 types? Eat what? Use what?
• Tinea cruris scrotom?
• Most common toe with pedis?
• Shape of lesion?
• Dimorphic?
• Prep?

Answer 7

• Microsporum, thrychophyton, epidermophyton; keritin; keratinase
• doesn’t touch it
• 4th toe
• pruritic lesion with central clearing
• yes
• KOH

Question 8

Candida albicans:

• Food source?
• Scrotom? (2)
• Thrush in who? (3)
• Vulvovaginitis in who? (2)
• Endocarditis in who?
• Tubules? Dimorphic? Hyphae? Budding what?

Answer 8

• Glucose
• Effected with sattelite colonies
• Immuno, steroids, DM
• AB use, DM
• IV drug users
• Germ; yes; pseudo; yeast

Question 9

Aspergillus:

• A stands for? Dimorphic?
• 3 clinical?
• Hyphae type? Angle?
• Found where?

Answer 9

• Acute angles; no
  1. ) ABPA: Allergic asoc
  2. ) Aspergilloma: Lung cavities post TB
  3. ) Aflatoxins: HCC
• septate; 45 degrees
• EVERYWHERE!!!

Question 10

Cryptococcus:

• Dimorphic? Looks like?
• Heavily encapsulated what?
• Clinical?
• Found where?
• Stains what? (2)
• Latex agglut find what?
• Lesion of brain description?

Answer 10

• No; capsular halos
• yeast
• Meningitis
• Pigeon droppings
• India/ Sabaroud agar
• Polysac. capsule
• Soap bubble

Question 11

Mucor/Rhizopus:

• Hyphae branching at?
• Mucormycosis effects who?
• Proliferate in BV’s with excess what?
• Penetrate what?
• Black necrotic what?

Answer 11

• wide angles
• DKA and leukemia patients
• Ketones
• Cribriform plate
• Eschar

Question 12

Pneumocytis Jirovecii:

• Clinical?
• Shape of yeast?
• Stain?

Answer 12

• PCP pneumonia
• Disc shape
• Silver stain

Question 13

Sporothrix schenkii:

• Lives on?
• Shape of dimorphic yeast?
• Pulsatile ulcer with nodules along?
• Treatment?
• Worse in who?

Answer 13

• Thorns
• Cigar shaped
• Lymphatics
• Potassium iodide
• Acoholics/ sarcoid

Question 14

• Eumycentoma: Granule type?
• Chromomycosis: 2 histology findings?
• Lobomycosis: Effects?
• Prothecosis: Type of organism? Effects what? Shape on histology?

Answer 14

• Sulfur
• Copper pennies, medlar bodies
• Dolphins
• Algae, effect bursa, morrula