Gamete Transport And Fertilization Flashcards

(82 cards)

1
Q

It re-absorbs a significant amount of rete fluid into the lumen of epididymal duct

A

Proximal head of the epididymis

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2
Q

It secretes fluid into the lumen of the epididymal duct

A

Distal head of epididymis

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3
Q

It lies parallel to the ductus deferens, wherein concentrations of sperm remain relatively constant

A

Body of epididymis (Corpus)

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4
Q

Sperm within this location are eligible for ejaculation. They move through the DD and into the pelvic urethra during sexual stimulation

A

Distal Tail (DT) of the Epididymis

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5
Q

Sperm within this location cannot be moved into an ejaculatory position following sexual stimulation.

A

Proximal tail (PT) of the Epididymis

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6
Q

These are abnormalities that originated during spermatogenesis in the testis.

A

Primary defects

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7
Q

These are abnormalities that occur during epididymal transport.

A

Secondary abnormalities

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8
Q

Head abnormalities

Middle-piece abnormalities (e.g., Abaxial attachment, Double / Coiled middle piece, Frayed, thin middle piece)

Tail abnormalities (Coiled-tail)

A

Primary abnormalities

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9
Q

Loose normal heads

Sperm cells with bent tails

Detachment of galea capitis (acrosome)

Cytoplasmic droplets

A

Secondary abnormalities

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10
Q

A process of climbing onto the female

A

Mounting

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11
Q

A successful entrance of the penis into the vagina

A

Intromission

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12
Q

It takes place in response to sensory stimulation of the glans penis

A

Ejaculation

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13
Q

Copulatory Behavior Steps

A

Mounting -> Intromission -> Stimulation of glans penis -> Emission -> Forceful muscle contraction -> Ejaculation / Semen expulsion

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14
Q

An ejaculation phased controlled by Sympathetic NS

A

Emission

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15
Q

An ejaculation phased controlled by Parasympathetic NS

A

Expulsion

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16
Q

Sperm is released from epididymis (DT)

Seminal fluid is released from seminal vesicle, prostates, and Cowper’s gland

Sperm and seminal fluid is mixed in prostatic urethra

A

Emission

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17
Q

Contraction of pelvic muscles

Forceful expulsion of semen through urethral meatus

A

Expulsion

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18
Q

Peristalsis and beating of cilia in this location brings ovum toward the isthmus

A

Infundibulum and Ampulla

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19
Q

It has fewer cilia and thicker smooth muscle (dictates movement of ovum)

A

Isthmus

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20
Q

Ovum transport in the oviduct takes ?

A

7 days

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21
Q

Via twitching movement, there is fluid flow in these areas

A

Seminiferous tubules and rete testes

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22
Q

There is smooth muscle contraction and the cilia prevents clogging via swirling motion to separate spermatozoa

A

Vas efferentia

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23
Q

There is also smooth contraction in these areas

A

Epididymis, Vas deferens, Pelvic urethra, Penile urethra

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24
Q

It is secreted during copulation and responsible for uterine contractility, sperm transport process, and ejaculatory process

A

Oxytocin

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25
How long does rapid transport phase take?
15 - 30 minutes
26
How long does sustained transport phase take?
6 - 12 hours
27
This occurs via contraction of muscularis layer of the RT during copulation however delivered spermatozoa are not viable
Rapid transport phase
28
The spermatozoa are transported into oviducts via “trickle-effect” effect, from reservoirs of cervix and UTJ
Sustained transport phase
29
The UTJ constricts in response to estradiol to restrict sperm passage
Tube-locking
30
Ejaculate is deposited into where, for these species? - Humans, Cattle, Sheep, Goats, Dogs, Cats, Rabbits
Cranial Vagina
31
Ejaculate is deposited into where, for these species? - Horses, Pigs, Camelids
Cervix / Uterus
32
Spermatozoa is lost via
Leukocyte phagocytosis Retrograde transport
33
Amount of sperm in ejaculate that reach the oviducts after a single mating?
Less than 1%
34
How do rodents mitigate retrograde loss?
Vaginal plug
35
How do dogs mitigate retrograde loss?
Copulatory “tie”
36
How do buck, ram, and rooster mitigate retrograde loss?
High sperm concentration
37
How do horses and pigs mitigate retrograde loss?
Semen deposited into the uterus
38
During estrus, secretion of ? from what part of cervical mucosa produces what?
Sulfomucins Apical portion Viscous mucus
39
Less viscous sialomucins are produced in the ?
Basal crypts
40
Changes undergone by spermatozoa in female genital tract that enables them to penetrate and fertilize an ovum
Sperm Capacitation
41
Where is the initial site of capacitation if semen is deposited in cranial vagina?
Cervix
42
Where is the initial site of capacitation if semen is deposited in cervix?
Uterus
43
Decapacitating factors
Surface molecules (glycoproteins and cholesterol) Seminal plasma protein coating
44
Surface molecules (glycoproteins and cholesterol) are secreted from?
Epididymis
45
Seminal plasma protein coating are secreted by?
Accessory glands: - Acrosome-stabilizing factors - Acrosin inhibitors
46
What removes cholesterol and increases spermatozoa motility?
Sterol acceptors
47
This is the sperm storage site; much more sperm observed in this site rather than the ?
Isthmus - Ampulla
48
Result of sperm capacitation
- Increased rate of metabolism - More rapid beating of flagellum (hyperactivated) - Plasmalemma protein changes -> allow sperm-egg binding and acrosome-reaction
49
This induces sperm chemotaxis
Follicular fluid
50
Duration of sperm residing in cow’s AIJ
1 - 2 hours
51
Duration of sperm residing in cow’s oviduct
18 - 24 hours
52
Duration of sperm residing in cow’s uterus
6 - 12 hours
53
Conditions for fertilization
Normal ovum & sperm Certain time (12 - 24 hours) Free / Open RT
54
Duration of fertilizable life of gametes in most mammals
Sperm (48 hours) Ovum (24 hours)
55
Duration of fertilizable life of gametes in bats
Live sperm cells can persist for several months (hibernation)
56
Duration of fertilizable life of gametes in domestic birds
Fertile sperm lasts for 2 - 15 weeks in Sperm Storage Tubules (SST) in the Utero-Vaginal Junction (UVJ)
57
A structure adjacent to the surface of ovum plasma membrane
Zona pellucida / Vitelline membrane
58
Space between the egg membrane and zona pellucida
Perivitelline membrane
59
Zona pellucida glycoprotein: ZP3
Primary sperm receptor
60
Zona pellucida glycoprotein: ZP2
Secondary sperm receptor
61
Zona pellucida glycoprotein: ZP1
Cross-links ZP2 and ZP3
62
Oocyte Activation
- Polyspermy block - Reactivation of Meosis II - Syngamy - DNA Replication
63
It is the depolarization of egg membrane during polyspermy block
Fast block
64
Fast block starts at ?
Fusion of Sperm and Egg Plasma Membranes
65
Fast block changes membrane potential from ?
- 70mV to + 20mv
66
Fast block duration ?
Approximately a minute
67
This is a polyspermy block that’s a cortical reaction and triggered by Ca2++ release from spermatozoa
Slow block
68
69
Fusion of cortical granules with egg cell membrane and subsequent release of contents results into?
Zona block
70
A formation of an impenetrable fertilization envelope/membrane
Zona block
71
Components of cortical granules
- Peroxidase - Hydrolase - Proteinase - Glycosaminoglycans (GAGs)
72
Peroxidases hardens the VM protein by?
Cross linking of tyrosine residues
73
Proteases and hydrolases ?
Trim off receptor proteins
74
Glycosaminoglycans (GAGs)
Attract water to raise VM
75
After ovulation, the oocyte is?
Suspended at Metaphase II
76
What reactivates Meiosis II?
Sperm penetration which triggers Ca2++ release
77
What then terminates meiosis?
Expulsion of 2nd polar body and formation of a zygote
78
Where does DNA replication begins?
In each pronuclei after sperm and ovum formation
79
Combination of two genomes is called?
Syngamy / Amphimixis
80
What does the sperm contributes to the egg?
Pronucleus and Centriole
81
This is the successive fertilization of two or more ova from the same ovulation especially different sires
Superfecundation
82
Superfecundation occurs in what type of animals?
Multiparous animals (e.g., dogs, cats, pigs, some sheep and goat breeds)