Gastric carcinoma Flashcards
1
Q
How common is gastric cancer?
A
4923 new cases of gastric cancer in the UK in 2007. Adenocarcinoma most common
2
Q
What is the pathology of gastric cancer?
A
- Columnar cell dysplasia
* Signet ring cell = very abnormal
3
Q
What are the risk factors/aetiology of gastric cancer?
A
- Diet – smoked cured meat, pickled veg
- H. pylori
- Bile reflux
- Hypochlorhydria - ↓ HCl
- Age – over 55
- Males
- Smoking
- Family history
4
Q
What are the signs/symptoms of gastric cancer?
A
• Dyspepsia – pain in gut • Weight loss • Vomiting • Dysphagia • Anaemia Palpable epigastric mass Palpable Vichow's node
5
Q
What diseases does gastric cancer present similarly to?
A
- Oesophageal carcinoma
* Peptic ulcer
6
Q
What investigations are carried out in suspected gastric cancer?
A
- FBC – anaemia
- LFTs
- Endoscopy – inc. biopsy
7
Q
What are the surgical treatments for gastric cancer?
A
- Stenting
- Partial/total gastrectomy
- Bypass surgery
8
Q
What are the pharmacological treatments for gastric cancer?
A
- Radiotherapy
- Chemotherapy
- Analgesia
- Anti-emetics
- Laxatives
9
Q
What are the non pharmacological treatments for gastric cancer?
A
• Nutritional supplements – if required
