Gastro

Question 1

Metabolic ketoacidosis with normal or low glucose

Answer 1

alcoholic ketoacidosis

Question 2

painless palpable gallbladder with mild jaundice

Answer 2

Pancreatic ca

Question 3

most common extraintestinal manifestation of IBD

Answer 3

arthritis

Question 4

primary sclerosing cholangitis is associated with what bowel condition

Answer 4

UC

Question 5

Difference between PSC and PCB

Answer 5

PCB is only intrahepatic ducts

Question 6

PSC risks developing

Answer 6

cholangiocarcinoma

Question 7

C diff rx

Answer 7

PO vanc/PO fidoxamicin

Second line OR in severe- PO vanc and IV metro

> 2 episodes- consider faecal transplant

Question 8

H pylori eradication test

Answer 8

urea breath test

Question 9

Mild UC presentation

Answer 9

<4 stools a day
Small amount of blood

Question 10

Mod UC presentation

Answer 10

4-6 stools/day
Varying blood

Question 11

Severe UC presentation

Answer 11

> 6 bloody stools/day

Systemic features eg NEWS high

Question 12

Severe UC first line rx

Answer 12

IV steroids

Question 13

Variceal bleed medication

Answer 13

terlipressin
Prophylactic antibiotics

consider beta blocker when stable to prevent recurrence

Question 14

alcoholic hepatitis rx

Answer 14

supportive

If GBS >9 consider steroids

Question 15

Ascites medical mx

Answer 15

spironolactone

consider adding loop diuretic if need

Question 16

Hepatorenal syndrome rx

Answer 16

HAS

Question 17

Chronic hep C rx

Answer 17

ribavirin
interferon alpha

Question 18

Hep B rx to prevent chronic

Answer 18

interferon alpha

Question 19

PBC antibody

Answer 19

anti mitochontrial ab

Question 20

how to diagnose PBC

Answer 20

antimitochontrial ab positive
and
deranged LFTs

Question 21

PBC treatment

Answer 21

ursodeoxycholic acid
?transplant

Question 22

What do ferritin and TIBC do in IDA

Answer 22

Ferritin low (depleted iron stores)
TIBC high (body is still able to use iron)

Question 23

What do ferritin and TIBC do in anaemia of chronic disease

Answer 23

Ferritin may be high due to inflammation

TIBC low (the iron is ‘locked away’ in the inflammation)

Question 24

Criteria for life threatening C diff

Answer 24

Hypotension
Partial or complete ileus
Toxic megacolon, or CT evidence of severe disease

Question 25

what antibiotics can cause cholestasis

Answer 25

co-amox fluclox erythro

Question 26

What diabetes drug causes cholestasis

Answer 26

sulfonylureas

Question 27

drugs that may cause liver cirrhosis

Answer 27

methotrexate methyldopa amiodarone

Question 28

Most common cause of Hepatocellular carcinoma

Answer 28

hepatitis B most common cause worldwide hepatitis C most common cause in Europe

Question 29

which extra-intestinal manifestations of Crohn's disease are related to disease activity?

Answer 29

Arthritis: pauciarticular, asymmetric Erythema nodosum Episcleritis Osteoporosis

Question 30

Drug that is a risk factor for C diff other than antibiotics

Answer 30

lansoprazole

Question 31

AST/ALT ratio in alcoholic hepatitis is

Answer 31

2:1

Question 32

First line in maintaining Crohn's remission

Answer 32

azathioprine or mercaptopurine (check TPMT) (2nd line MTX) STOP SMOKING

Question 33

Inducing Crohn's remission meds

Answer 33

Steroids Mesalazine 2nd line Infliximab in refractory or fistulating

Question 34

Disease most likely associated with PCB

Answer 34

Sjogren's syndrome (80%)

Question 35

When are IV PPIs given in acute GI bleed

Answer 35

after endoscopy, if there is evidence of recent non-variceal haemorrhage

Question 36

When are GBS and Rockall scores used

Answer 36

GBS on presentation of UGI bleed Rockall post endoscopy (percentage risk of rebleeding and mortality)

Question 37

Patients with UGI bleed who take warfarin should get what

Answer 37

prothrombin complex

Question 38

TIPS procedure is for what

Answer 38

variceal bleeds if not controlled with ligation/injection

Question 39

bloody diarrhoea is more characteristic of which type of IBD

Answer 39

UC

Question 40

intermittent dysphagia (difficulty swallowing), halitosis (bad breath), and nocturnal coughing are characteristic of what

Answer 40

pharyngeal pouch

Question 41

cyclical vomiting syndrome is associated with what other condition

Answer 41

migraines

Question 42

Metaplastic columnar epithelium on oesophageal biopsy

Answer 42

barretts

Question 43

type of oesophageal ca linked with GORD

Answer 43

Adenocarcinoma

Question 44

hereditary non-polyposis colorectal carcinoma also increases risk of what other type of cancer

Answer 44

endometrial