Gastro 2 Flashcards

1
Q

achalasia surgical mx?

A

heller cardiomyotomy

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2
Q

Mx of achalasia?

A

balloon dilatation
heller cardiomyotomy

botoulinum toxin

nitrates / CCB

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3
Q

alcoholic hepatitis signs

A

GGT raised
ast:alt ratio >2

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4
Q

small intestinal bacterial overgrowth is developed by?
RF

A

DM

autonomic neuropathy

scleroderma

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5
Q

how to differentiate between Alcoholic ketoacidosis and Diabetic ketoacidosis?

A

normal / low glucose

with ketones

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6
Q

mx of alcoholic ketoacidosis?

A

non-diabetic euglycaemic

infusion of saline and thiamine

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7
Q

why do coeliacs need pneumococcal vaccine?

A

hyposplenism

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8
Q

neuroendocrine tumour

A

secrete serotonin

diarrhoea
bronchial NET > SS
liver mets > SS

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9
Q

Ix carcinoid syndrome / NET

A

Investigation
urinary 5-HIAA
plasma chromogranin A y

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10
Q

signet ring cells

A

gastric adenocarcinoma

large vacuole containing mucin

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11
Q

suspected pharyngeal pouch
Investigation?

A

barium swallow w fluoroscopy

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12
Q

chronic mesenteric ischaemia?

A

colicky post prand meal

abdominal bruit
weight loss

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13
Q

Bowel Ischaemia RF

A

age
A fibrillation
CVD; smoke/ HTN/ DM
cocaine

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14
Q

Ix bowel ischaemia

Imaging of choice?

A

CT

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15
Q

acute mesenteric ischaemia?

A

small bowel ischaemia
Afib

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16
Q

ischaemic colitis?

A

acute but transient

large bowel

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17
Q

what is a watershed area?
what sign on xray?

A

splenic flexure
SMA /IMA

thumbprinting on xray
mucosal oedema / haemorrhage

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18
Q

budd chiari syndrome
Imaging?

A

hepatic vein thrombosis

> USS with doppler flow studies

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19
Q

what is the triad for budd chiari syndrome

A

abdominal pain
ascites
tender hepatomegaly

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20
Q

Causes of budd chiari syndrome

A

polycythaemia rubra vera
thrombophilia activated protein C
pregnancy COCP

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21
Q

Pyogenic Liver Abscess mx?

A

drainage
abx

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22
Q

which organism in liver abscess?

A

e coli (adults)

staph aureus (children)

23
Q

what abx?

A

amoxicillin
ciprofloxacillin
metronidazole

24
Q

Reintroduce gluten for at least _______ and arrange serological tests

25
toxic megacolon
transverse colon >6cm in diameter systemic upset Ix: abdo Xray
26
role of endoscopy after a Upper GI bleed?
endoscopy within 24 hours
27
Resus upper GI bleed active bleeding? if on warfarn?
ABC wide bore IV access 2 platelet transfusion Prothrombin complex concentrate
28
FFP given in upper gi bleed when?
fibrinogen <1g/l INR >1.5
29
C diff RF
abx > clindamycin >cephalosporins PPI
30
dysphagia
difficulty swallowing
31
odynophagia?
pain on swallowing
32
Truelove and Witts severity index what is it for? what is the criteria?
UC 37.8^C 90 beats per minute Anaemia (105g/L) ESR >30 Temp Rate Uh (neami) EESR >30
33
Dx of Oesophageal cancer?
upper GI endoscopy w biospy USS CT-Scan fdg-pet ct
34
PSC has what antibodies?
p- ANCA
35
what is PSC?
inflammation and fibrosis intra and extra hepatice bile ducts
36
gold standard Ix for PSC?
MRCP ERCP - more invasive > beaded
37
peutz jeghers syndrome what lesions on colonoscopy?
hamartomas
38
co amoxiclav
amoxicllin clavulanate hepatotoxic = cholestasis
39
Treatment for oesophageal cancer operable?
t1n0mo surgical resection ivor lewis oesophagectomy adjuvant chemo
40
Neoadjuvant chemoradiotherapy followed by surgical resection oesophageal cancer
locally advanced cancers to downstage it
41
metoclopramide
d2 receptor antagonist pro kinetic = promotes gut peristalsis
42
how does Metoclopramide decrease nausea?
promotes gut peristalsis 5-HT3/5 which inhibits chemoreceptor trigger zone of the medulla
43
SAAG >11 ascites
portal htn > cirrhosis >RHF > budd chiari
44
SAAG <11
hypoalbumin > nephrotic syndrome malnutrition
45
therapeutic abdo paracentesis?
albumin cover needed ciprofloxacin <15g/l of protein
46
bulk forming laxative?
isphagula usk
47
osmotic laxative
macrogol
48
UC histology
depleted goblet cells and mucin from gland epithelium
49
crohns hsitology
goblet cell increased granuloma
50
carcinoid syndrome can affect the heart how?
right side of the heart > tricuspid insufficiency >pulmonary stenosis
51
Mx of perianal fistula
oral metronidazole seton drain > metronidazole >ciprofloxacin
52
pre-operative workup for a patient undergoing a Nissen fundoplication for treatment-resistant GORD
oesophageal manometry oesophageal pH
53