GASTRO-INTESTINAL SMOOTH MUSCLE SPASM Flashcards Preview

gastro-intestinal system > GASTRO-INTESTINAL SMOOTH MUSCLE SPASM > Flashcards

Flashcards in GASTRO-INTESTINAL SMOOTH MUSCLE SPASM Deck (6)
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1

What causes gastro-intestinal smooth muscle spasms ?

IBS
IBD
bowel colic in palliative care

2

How are antimuscarinis drugs useful in gastro-intestinal smooth muscle spasm?

reduces intestinal motility.
S/E of antimuscarinics: dilate pupil, inhibit salivation, accelerates heart beat, dilate bronchi, inhibits digestions, constipation, stimulates glucose release, inhibits peristalsis and secretion, relaxes bladder, angle-closure glaucoma, drowsiness

3

What are the cautions of antimuscarinic drugs ?

susceptibility to angle-closure glaucoma
conditions causing tachycardia: hyperthyroidism
cardiovascular disease: arythmias, CHF

4

What are the contraindications of antimuscarinic drugs ?

prostatic enlargment, urinary retention
paralytic ileus, GI obstruction, megacolon
Myasthenia graves
narrow angle glaucoma

5

Antimuscarinic side effects?

blurred vision, urinary retention, constipation, dry mouth

6

Name antispasmodics available ?

-mebeverine
-alverine ( dizziness, driving warning)
both are contraindicated in paralytic ileus
-pepermint oil ( heartburn, local irritation of mouth, oesophagus )