Gastrointestinal endoscopy Flashcards

(47 cards)

1
Q

risk of bleeding

clean based ulcer

A

3-5%

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2
Q

risk of bleeding

flat pigmented spots covering the ulcer base

A

10%

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3
Q

risk of bleeding

adherent clots covering the ulcer base

A

20%

endoscopic therapy needed

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4
Q

risk of bleeding

platelet plug protruding form vessel wall in the base of an ulcer (sentinel or visible vessel)

A

40%

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5
Q

risk of bleeding

active spurting from an ulcer

A

> 90% bleeding without therapy

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6
Q

indicated for first bleed from large oesophageal varices

A

EVL (endoscopic variceal ligation)

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7
Q

Rx bleeidng from large gastric funds varices

A

endoscopic cyanoacrylate “glue” injection

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8
Q

MC site dieulafoys lesion

A

lesser curvature of proximal stomach

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9
Q

presence of linear furrows and multiple corrugated rings throughout narrowed esophagus

A

feline esophagus

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10
Q

when to repeat colonoscopy

1 or 2 small (

A

Repeat colonoscopy in 5 years

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11
Q

when to repeat colonoscopy

3 to 9 adenomas, or any adenoma 1 cm or containing high-grade dysplasia or villus features

A

Repeat colonoscopy in 3 years; subsequent colonoscopy based on findings

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12
Q

when to repeat colonoscopy:

10 adenomas

A

Colonoscopy in

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13
Q

when to repeat colonoscopy:

Piecemeal removal of a sessile polyp

A

Exam in 2 to 6 months to verify complete removal

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14
Q

when to repeat colonoscopy:

Small (

A

Colonoscopy in 10 years

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15
Q

when to repeat colonoscopy:

>2 serrated polyps, or any serrated or hyperplastic polyp 1 cm

A

Repeat colonoscopy in 3 years

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16
Q

when to repeat colonoscopy:

Incompletely removed serrated polyp 1 cm

A

Exam in 2 to 6 months to verify complete removal

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17
Q

when to repeat colonoscopy:

Colon cancer

A

Evaluate entire colon around the time of resection, then repeat colonoscopy in 3 years

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18
Q

when to repeat colonoscopy:

Long-standing (>8 years) ulcerative colitis or Crohn’s colitis, or left-sided ulcerative colitis of >15 years’ duration

A

Colonoscopy with biopsies every 1 to 3 years

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19
Q

when to do colonoscopy:
First-degree relatives with only small tubular adenomas
Single first-degree relative with CRC or advanced adenoma at age 60 years

A

Same as average risk

20
Q

when to do colonoscopy:

Single first-degree relative with CRC or advanced adenoma at age

A

Colonoscopy every 5 years beginning at age 40 years or 10 years younger than age at diagnosis of the youngest affected relative

21
Q

when to do colonoscopy:

FH of FAP

A

Sigmoidoscopy or colonoscopy annually, beginning at age 10–12 years

22
Q

when to do colonoscopy:

Family History of HNPCC

A

Colonoscopy every 2 years beginning at age 20–25 years until age 40, then annually thereafter

23
Q

Duration chronic diarrhea

24
Q

Ct scan findings UC

A
  • mild mural thickening
  • inhomogeneous wall density
  • absence of small bowel thickening
  • increased perirectal and pre sacral fat
  • target appearance of rectum
  • adenopathy
25
indication for colectomy in patients with massive hemorrhage in UC
6-8 units of blood are required in 24-48 hours
26
Define toxic megacolon
Transverse of right colon with a diameter of >6 cm, with loss of haustration in patients with severe attacks of UC
27
Most dangerous complication of UC
perforation
28
in 5% of UC patients, triggers toxic megacolon
electrolyte abnormalities | narcotics
29
Mortality rate of perforation in UC
15%
30
incidence of stricture in UC
5-10%
31
Two patterns of disease in crohn's
1) fibrostenotic obstructing pattern | 2) penetrating fistulous pattern
32
IBD drug blocks production of IL2 by T helper lymphocytes
Cyclosporine
33
inhibits dihydrofolate reductase, resulting in impaired DNA synthesis
MXT
34
rare but serious complication of MXT therapy
hypersensitivity pneumonitis
35
macrolide antibiotics with immunomodulatory properties similar to CSA
tacrolimus
36
nearly universally fatal lymphoma in patients with Crohn's disease
Hepatosplenic T cell lymphoma
37
AE cyclosporin
renal
38
MOA infliximab
chimeric IgG1 antibody active against TNF alpha
39
remission rate of GC in UC
60-70%
40
purine analogues employed in glucocorticoid dependent IBD
Azathioprine | 5 mercaptopurine
41
showed that of the patients who experience an initial response to infliximab, 40% of these will maintain remission for at least 1 year with repeated infusions of infliximab every 8 weeks
ACCENT I | A Crohn's Disease Clinical Trial Evaluating Infliximab in a New Long Term Treatment Regimen
42
Infliximab is also effective in CD patients with refractory perianal and enterocutaneous fistulas
ACCENT II
43
what to do to prevent development of antibodies to infliximab (ATI), which is associated with an increased risk of infusion reactions and a decreased response to treatment
giving on-demand or episodic infusions rather than periodic (every 8 weeks) infusions because patients are more likely to develop ATI
44
compared infliximab plus azathioprine, infliximab alone and azathioprine alone in immunomodulator and biologic naïve patients with moderate-to-severe Crohn's disease
SONIC
45
recombinant human monoclonal IgG1 antibody containing only human peptide sequences and is injected subcutaneously
Adalimumab
46
recombinant humanized immunoglobulin G4 antibody against 4 integrin that is effective in the induction and maintenance of remission in CD patients
Natalizumab
47
flat HGD encountered
UC colectomy | CD colectomy or segmental resection