GB Flashcards
1
Q
PASMCs
A
Pulmonary artery smooth muscle cells
2
Q
PDGFR
A
plateled-derived growth factor receptor
3
Q
CSF I R
A
colony stimulating factor I receptor
4
Q
c-KIT
A
stem cell factor receptor
5
Q
Seralutinib
A
Novel, potent, clinical stage inhibitor of
PDGFR alfa/beta
CSF I R
and c-KIT
6
Q
TORREY, a phase 2 study
primary endpoint
A
the change from baseline to Week 24 in PVR by RHC
7
Q
TORREY, a phase 2 study
the secondary endpoint
A
the change in distance from baseline to Week 24 achieved in the 6MWT
8
Q
TORREY, a phase 2 study
CT sub-study
A
will examine the effect of seralutinib on pulmonary vascular remodeling
9
Q
TORREY, a phase 2 study
a separate heart rate monitoring sub-study
A
will examine the effect of seralutinib on cardiac effort during the 6MWT
