GBP2 Flashcards
(9 cards)
1
Q
What does ADME stand for
A
Absorption, Distribution, Metabolism, Excretion
2
Q
What does zero order kinetics mean
A
rate independent of concentration
3
Q
What does first order kinetics mean
A
rate dependant on concentration
4
Q
What does bioavailability mean
A
the fraction of drug absorbed (oral)
5
Q
What does the salt factor refer to
A
The proportion of medicine which is active drug
6
Q
How would you calculate amount of drug
A
dose x bioavailability x salt factor
7
Q
What does Vd refer to
A
the apparent volume in which the drug is dissolved in the body
8
Q
How is a drug eliminated from the body
A
hepatic metabolism and renal excretion
9
Q
What does k denote
A
the fraction eliminated per unit time (rate constant)
