Gene expression Flashcards
Allele
An alternate form of a gene (e.g blue eyes)
Chromosome
A long molecule of DNA
Gene
A length of DNA that codes for a particular trait (e.g eye colour)
DNA
It’s a double helix that contains the genetic code. It’s made up of sugar, phosphate and nucleotide.
Phentoype
Is the physical expression of a trait
Gentoype
The genetic material of a trait
DNA triplet
A series of 3 bases in DNA, each triplet codes for a specific amino acid.
Ribosome
An organelle where translation (the making of proteins) takes place
mRNA
A single stranded copy of a gene, that carries the genetic code from the nucleus to a ribosome. `
Transcription
The process of making mRNA from DNA.
Translation
The process of making a protien from mRNA
Template strand
A single strand of DNA where complimentary nucleotides are added to make mRNA
tRNA
A type of RNA with an anticodon on one end and a specific amino acid attached to the other end.
Mutation
A permanent change in the base sequence of DNA, that may result in new alleles.
Enzyme
A type of protien which functions as biological catalyst to speed ip reactions inside living things.
Substrate
The reactant that is catlysed bya specific enzyme
Base substitution mutation
Is a form of mutation where a single nucleotide base is replaced or substituted with another.
Same-sense
The substituted base does not cause a change in the amino acid sequence
Missense
Causes a change in the amino acid sequence, but does not cause a change in the shape or function of the protein.
Nonsense
Substituted base results in the production of a stop codon, has a severe impact on the protein formed.
Single base insertion
A form of DNA mutation where one base is added into the DNA chain, changing the genetic code dramatically.
Single base deletion
A form of DNA mutation where one base is removed from the DNA chain, and lost forever.
Reading frame-shift
A genetic mutation caused by a deletion or insertion of a base in a DNA sequence that shifts the way the sequence is read (in triplets).
Examples of mutagens
Chemicals
Ultraviolet Light
Radiation