Gene Expression Flashcards Preview

Biology 7401/2 > Gene Expression > Flashcards

Flashcards in Gene Expression Deck (11):
1

What are totipotent cells?

can produce any body cell
during development, don't translate all DNA so result is specialisation

2

What are pluripotent cells?

Divide in unlimited numbers
Stem cells
Treat human disorders

3

What are unipotent cells?

Differentiate along one lineage

4

Induced Pluripotent?

reprogramming adult body cells
express transcription factors

5

Stem cells are used for:

Bone marrow transplants
Spinal cord injury
Transplants

6

What are the ethical considerations for using stem cells?

Religious arguements
IVF rejections
Who has ownership?

7

What is epigenetic control?

Control of gene expression due to control of markers on histones. May be from environmental influences.

8

What is increased Methylation of histones?

More Methyl groups
More attraction
Gene densely packed
Transcription factors cant get in
Gene not expressed

9

What is increased Acetylation of histones?

More Acetyl groups
Less Attractions
Gene more Apart
Transcription factors can get in
Gene is expressed.

10

What are the transcription factors?

Promoters: target DNA site
Activators: helps RNA polymerase binds
Repressors: bind to target gene to prevent RNA polymerase binding

11

What is the role of Oestrogen?

steroid hormone
creates an activator
helps RNA polymerase to bind

(may cause cancers???)