Flashcards in Gene Expression Deck (11):
What are totipotent cells?
can produce any body cell
during development, don't translate all DNA so result is specialisation
What are pluripotent cells?
Divide in unlimited numbers
Treat human disorders
What are unipotent cells?
Differentiate along one lineage
reprogramming adult body cells
express transcription factors
Stem cells are used for:
Bone marrow transplants
Spinal cord injury
What are the ethical considerations for using stem cells?
Who has ownership?
What is epigenetic control?
Control of gene expression due to control of markers on histones. May be from environmental influences.
What is increased Methylation of histones?
More Methyl groups
Gene densely packed
Transcription factors cant get in
Gene not expressed
What is increased Acetylation of histones?
More Acetyl groups
Gene more Apart
Transcription factors can get in
Gene is expressed.
What are the transcription factors?
Promoters: target DNA site
Activators: helps RNA polymerase binds
Repressors: bind to target gene to prevent RNA polymerase binding