Flashcards in Gene Therapy - Whitt Deck (7):
What is gene therapy ?
Gene therapy is a novel approach to treating diseases based on modifying the expression of a person's genes toward a therapeutic goal.
What is somatic gene therapy ?
Manipulation of the genes of a patient in a manner that provide the patient with benefit but will not be passed down to their offspring.
What is germline gene therapy ?
Manipulation of a patients germ line genes in a manner that they will be passed to the next generation.
How do you deliver your gene of interest to the target area in the genome
What are the two main types of vectors ?
1. Attenuated or modified viruses
2. Non-Viral Vectors such as liposome transfection and Gene Gun
How does a gene gun work ?
DNA can be conjugated to gold particles and delivered. Used primariy to give DNA vaccines