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Flashcards in General anesthesia Deck (9)
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1

What are some normal physiological responses to being pregnant?

Decreased serum albumin, increased alpha and beta globulins, increased fibrinogen and factor VII, transferrin and TIBC increases, Fe decreases

2

Which of the following is NOT affected by volatile anesthetics? SSEPs, MEPs, AEPs, VEPs

Auditory evoked potentials

3

Describe the mechanism of action of PTH

PTH is activated when calcium is low. It stimulates osteoclast activity to cause bone reabsorption, it activates calcitriol to create vitamin D which stimulates Ca reabsorption in the gut, it increases ca reabsorption in the DISTAL tubule of the kidney

4

What electrolyte abnormality is seen in respiratory alkalosis?

Hypocalcemia: negatively charged ions are bound to H+. When the body becomes alkalotic, the H+ ions leave the negatively charged proteins and Ca2+ binds instead. This then leads to hypocalcemia

5

What types of gases will increased MV have the largest effect on?

More soluble gases (in order of most soluble to least: Halothane, isoflurane, sevoflurane, N20, desflurane)

6

What artery are you at risk for inecting local anesthetic when you are doing an inter scalene block?

The vertebral artery

7

Define an acid and base in chemistry terms

Acids donate protons and bases receive protons

8

What is CBF directly related to?

PaCO2, not H+, therefore respiratory acidosis increases CBF more than metabolic acidosis

9

What metabolic change is seen with TPN?

Hypophosphatemia, this is caused by increased insulin 2/2 increased glucose. This leads to an intracellular shift of phosphate into the cell. This is the principle of re-feeding syndrome and why you cannot give TPN to malnourished people who already have low P