General immunology AB Flashcards by Anna Balabanski

Q

What do toll-like receptors do?

A

Act via NF-kB to upregulate antimicrobial peptides (IL-1, 6, 8, B7)

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Q

What does TLR4 bind?

A

Bacterial LPS

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Q

What is the clinical significance of TLR3 deficiency?

A

Some children with herpes simplex encephalitis

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