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Flashcards in General Principles of Pharmacology Deck (37)
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1

Adverse Reaction

Undesirable drug effect

2

Allergic Reaction

Immediate hypersensitive reaction by the immune system; it presents as itching, gives, swelling, and difficulty breathing

3

Anaphylactic Shock

Sudden, severe hypersensitivity reaction with symptoms that progress rapidly and may result in death of not treated;

4

Angioedema

Localized wheals or swellings in subcutaneous tissue or mucous membranes, which may be due to an allergic response;

5

Absorption

A drug is moved from the site of administration to body fluids; first process during pharmacokinetics.

6

Controlled Substance

Drugs that have the potential for abuse and dependency, both physical and psychological

7

Cumulative Drug Effect

When the body is unable to metabolize and excrete one dose of a drug before the next is given

8

Distribution

Drug moves from circulation to body tissue or a target site

9

Drug Idiosyncrasy

Any unusual or abnormal response that differs from the response normally expected to a specific drug and dosage

10

Drug Tolerance

Decreased response to a drug, requiring an increase in dosage to achieve the desired effect

11

Excretion

Elimination of a drug from the body

12

First-Pass Effect

Action by which an oral drug is absorbed and carried directly to the liver, where it is inactivated by enzymes before it enters the general bloodstream

13

Half-Life

Time required for the body to eliminate 50% of a drug

14

Herbal Medicine

Type of complementary/alternative therapy uses plants or herbs to treat various disorders

15

Hypersensitivity

Undesirable reaction produced by a normal immune system

16

Metabolism

Drug changed to a form that can be excreted

17

Metabolite

Inactive form of the original drug

18

Nonprescription Drugs

Drugs that are designated by the U.S Food and Drug Administration to be safe and obtainable without a prescription

19

Pharmaceutic

Pertaining to the phase during which a drug dissolves in the body

20

Pharmacodynamics

Study of the drug mechanisms that produce biochemical or physiologic changes in the body

21

Pharmacokinetics

Study of drug transit (activity) after administration

22

Physical Dependency

Habitual use of a drug, where negative physical withdrawal symptoms result from abrupt discontinuation

23

Prescription Drugs

Drugs that the federal government has designated as potentially harmful unless their use is supervised by a licensed health care provider

24

Psychological Dependency

Compulsion or craving to use a substance to obtain a pleasurable experience

25

Receptor

In pharmacology, a reactive site on the surface of a cell; when a drug binds to and interacts with the receptor, a pharmacological response occurs

26

Teratogen

Drug or substance that causes abnormal development of fetus, leading to deformities

27

Toxic

Poisonous or harmful

28

Nonprescription Drugs

Drugs that are designated by the U.S Food and Drug Administration to be safe and obtainable without a prescription

29

Pharmaceutic

Pertaining to the phase during which a drug dissolves in the body

30

Pharmacodynamics

Study of the drug mechanisms that produce biochemical or physiologic changes in the body