General Questions - Final Coverage Flashcards
(82 cards)
Which of the following statements about the pathogenesis of Dermatophilosis is FALSE?
A) D. congolensis zoospores are attracted to skin sites by the respiratory efflux of low concentrations of carbon dioxide.
B) Hyphae penetrate into the living epidermis, causing an acute inflammatory reaction.
C) Natural resistance to acute infection is primarily due to established immunity following initial exposure.
D) In chronic infections, wet scabs enhance the proliferation and release of zoospores from hyphae.
Natural resistance to acute infection is primarily due to established immunity following initial exposure.
A sheep presents with matted wool, crusts, and exudates over its back and sides. Upon examination, the animal is painful but shows no signs of pruritus. These clinical signs are most consistent with:
Mycotic dermatitis
In cattle, which stage of Dermatophilosis lesion progression is characterized by “hairs matted together as paintbrush lesions”?
Stage 1
A dairy cow develops papular, crusted lesions on its udder. Which of the following predisposing factors is LEAST likely to be associated with this specific lesion distribution in Dermatophilosis?
A) Prolonged wetting of the skin due to standing in deep water.
B) Mechanical vectors like biting flies.
C) Tick infestation in the udder area.
D) Reduced or deficient normal skin barriers.
Mechanical vectors like biting flies.
A group of goats is experiencing an outbreak of a highly contagious disease. Clinical signs include a sudden fever of 40.5 C, mucopurulent nasal discharge with a putrid odor, necrotic stomatitis affecting the lower lip and gum, and severe diarrhea. Post-mortem examination reveals “zebra-striped” appearance in the rectum and sloughed Peyer’s patches. These findings are pathognomonic for?
Peste des petits ruminants
Regarding the lesions of Peste des petits ruminants (PPR), which of the following organs is least commonly and severely affected?
A) Abomasum
B) Large Intestine
C) Rumen
D) Peyer’s Patches
Rumen
Which of the following is typically observed early in the clinical course of acute Peste des petits ruminants?
A) Profuse diarrhea leading to hypothermia and death.
B) Bronchopneumonia characterized by coughing.
C) Serous nasal discharge.
D) The development of the characteristic “zebra-striped” appearance in the rectum.
Serous nasal discharge
In the pathogenesis of Bovine Spongiform Encephalopathy (BSE), after the agent crosses the mucosal barrier in the digestive tract, where does it primarily accumulate and replicate before infecting the enteric nervous system?
Gut-associated lymphoid tissues (GALT)
A 4-year-old dairy cow exhibits subtle behavioral changes, including increased nervousness, difficulty negotiating obstacles, and reluctance to be milked. Over several weeks, these signs progress to include hypermetria and tremors. A definitive diagnosis would rely on characteristic lesions in the brain and spinal cord, specifically?
Neuronal vacuolation, degeneration and loss, and astrocytic hypertrophy and hyperplasia.
Dairy cows were affected by BSE three times more often than beef cattle during the European outbreak. The most probable reason for this disparity, is?
Dairy cows were more likely to be fed animal-source protein supplements.
What is the primary mechanism by which the Blue Tongue virus causes clinical disease in ruminants?
Endothelial damage, hemorrhage, vascular occlusion, and tissue edema.
A sheep with Blue Tongue is suspected. What clinical signs, if observed, would be most indicative of a severe acute case?
Cyanotic and protruding tongue, torticollis, and abortion.
Post-mortem examination of a sheep reveals distinctive hemorrhages at the base of the pulmonary artery, severe alveolar edema, and congestion of the hoof laminae. These lesions are highly suggestive of?
Blue Tongue
A cattle farmer observes lesions on his herd primarily located on the head, ears, axillae, groin, and scrotum. Based on the pathogenesis of Dermatophilosis, which of the following predisposing factors is most likely responsible for initiating these specific lesions?
A) Prolonged periods standing in deep water and mud.
B) Mechanical transmission by biting flies.
C) Infestation by ticks.
D) Spiny plants causing abrasions.
Infestation by ticks.
In chronic Dermatophilosis in sheep, the “lumpy wool” form is characterized by?
Pyramid-shaped masses of scab material bound to wool fibers, primarily on dorsal areas.
A goat producer reports a sudden increase in body temperature in several young animals, accompanied by a dull coat, dry muzzle, and depressed appetite. The morbidity and mortality rates in this outbreak are observed to be exceptionally high, near 90%. Based on the provided information, which of the following statements about this scenario is TRUE?
A) The high morbidity and mortality are atypical for PPR.
B) The incubation period for this disease is likely less than 24 hours.
C) Older animals in the herd would likely show similar or even higher mortality rates.
D) The elevated morbidity and mortality rates are consistent with PPR, especially in young animals.
The elevated morbidity and mortality rates are consistent with PPR, especially in young animals.
Which of the following is an expected post-mortem finding in a case of Peste des petits ruminants, particularly affecting the digestive tract?
A) Extensive involvement and severe lesions in the rumen and reticulum.
B) Regularly outlined erosions with red, raw floors oozing blood in the abomasum.
C) More severe lesions in the small intestines than in the large intestines.
D) Absence of any lymphoid tissue changes.
Regularly outlined erosions with red, raw floors oozing blood in the abomasum.
The spread of the BSE agent from the gut-associated lymphoid tissues (GALT) to the brain primarily occurs via which pathway?
A) Hematogenous spread through the circulatory system, directly infecting the cerebral cortex.
B) Retrograde axonal transport through sensory neuronal pathways.
C) Efferent neuronal pathways (parasympathetic and sympathetic) originating from the enteric nervous system (ENS).
D) Direct invasion of the brain tissue from the nasal cavity.
Efferent neuronal pathways (parasympathetic and sympathetic) originating from the enteric nervous system (ENS).
Classical BSE is most commonly diagnosed in cattle within which age range?
3-6 years old.
A prominent clinical sign of acute Blue Tongue that distinguishes it from diseases primarily causing skin lesions or neurological signs is:
A) Painful, non-pruritic crusts on the dorsal midline.
B) Hyperesthesia and difficulty negotiating obstacles.
C) Cyanotic tongue and hyperaemia of the muzzle, lips, and face leading to oedema.
D) Necrotic stomatitis affecting the lower lip and gum.
Cyanotic tongue and hyperaemia of the muzzle, lips, and face leading to oedema.
In fatal cases of Blue Tongue with pulmonary complications, what is a characteristic finding in the lungs?
Severe alveolar oedema and the bronchial tree filled with froth.
Which of the following cells are directly involved in the systemic replication of the Blue Tongue virus, leading to the characteristic pathological changes?
A) Neurons and astrocytes.
B) M-cells and dendritic cells.
C) Phagocytic cells of the epidermis.
D) Hematopoietic cells and endothelial cells.
Hematopoietic cells and endothelial cells.
Which of the following statements accurately describes the early pathogenesis of classical scrapie after oral ingestion of PrPsc?
A) PrPsc directly infects the brainstem and spinal cord, leading to immediate neurodegeneration.
B) PrPsc bypasses the gut-associated lymphoid tissue (GALT) and replicates exclusively in peripheral nerves.
C) PrPsc enters the palatine tonsil and crosses the intestinal wall, primarily accumulating in the GALT, with Peyer’s patches being a crucial entry point.
D) The lymphoid dissemination phase precedes the entry into the gut, as PrPsc is first absorbed into the bloodstream.
PrPsc enters the palatine tonsil and crosses the intestinal wall, primarily accumulating in the GALT, with Peyer’s patches being a crucial entry point.
A 3-year-old sheep exhibits progressive neurological signs, including ataxia and hypersensitivity to stimuli. The owner also reports that the animal is frequently rubbing against fences and objects, causing wool loss. Based on these clinical signs, which form of scrapie is most likely?
Classical scrapie, given the age and presence of pruritus.