GENUS CHLAMYDIA/CHLAMYDOPHILA

Question 1

Initially Chlamydia, but later on called as

Answer 1

Chlamydophila (2 spp)

Question 2

Chlamydia species

Answer 2

C. Trachomatis
C. Pneumoniae
C. Psittaci

Question 3

General Characteristics of Chlamydia

Answer 3

• Obligate intracellular (cannot grow on bacterial culture)
• sensitive to Sulfa drugs
• Has 2 dinstinct forms

Question 4

Distinct forms of Chlamydia

Answer 4

1. Elementary body (infectious)
2. Reticulated (non-infectious)

Question 5

Characteristics of Elementary body

Answer 5

• Spore-like
• Resistant to environmental physical stress
• outer membrane is like gram (-)
• general composition: MOMP
  (Major outer membrane protein)

Question 6

1 cause of preventable eye blindness

Answer 6

C. Trachomatis

Question 7

Clinical significance of C. Trachomatis

Answer 7

• TRIC - Trachoma Inclusion Conjuntivitis
• LGV (Lymphogranuloma Venereum) - STD, venereally aquired
• Reiter’s syndrome, Reactive Arthritis

Question 8

Pear shaped, Elementary body

Answer 8

C.pneumoniae

Question 9

C.pneumoniae can cause

Answer 9

TWARS
Taiwan Acute Respiratory Strain

Question 10

C.psittaci causes

Answer 10

Parrot fever/ Ornithosis / Psittacosis

Question 11

Psittacosis is acquired through

Answer 11

Contact with infected birds and droppings

Question 12

Chlamydia with Elementary body

Answer 12

Trachomatic
Pneumoniae

Question 13

Chlamydia that are respiratory pathogen

Answer 13

Pneumoniae
Psittaci

Question 14

Culture used for Chlamydia

Answer 14

McCoy cells
HeLa
Buffalo green monkey

Question 15

Gold standard before for Chlamydia

Answer 15

Cell culture

Question 16

Current gold standard for C. Trachomatis

Answer 16

NAAT
(Nucleic Acid Amplification test)