GI- 10% Flashcards

(85 cards)

1
Q

what age group is appendicitis MC in

A

10-30yo

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2
Q

what is duodenal atresia commonly associated with

A

down syndrome

polyhydramnios

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3
Q

what are the first signs of duodenal atresia

A

abd distention + BILIOUS vomiting shortly after birth

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4
Q

what do you see on an AXR of a pt w duodenal atresia

A

double bubble sign- distended duodenum

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5
Q

tx of duodenal atresia

A

decompress GI tract, lytes + fluids, surgery

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6
Q

what is esophageal atresia commonly associated w

A

TEF

polyhydramnios

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7
Q

dx of esophageal atresia

A

NG tube + CXR (10-15cm down)

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8
Q

what type of contrast should be used in fluoroscopy for pt with esophageal atresia

A

water-soluble
should be removed promptly
no barium- caustic

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9
Q

what is the normal timeline for GER in newborns

A

start 2-3wks s/p birth
peaks 4-5mo
most improve completely by 9-12mo

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10
Q

what 2 factors contribute to GER in newborns

A

underdeveloped LES

lower diaphragm

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11
Q

tx of GER

A

burping, hold upright x30min s/p feeds
thicken formula w infant cereal
if feeding problems/severe sx- antacids, PPIs, H2 antagonists

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12
Q

why is PPI use limited in newborns with GERD

A

decreased calcium + magnesium absorption
problems w bone metabolism
inc GI infxns
acute interstitial nephritis

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13
Q

what types of hepatitis can develop into chronic hepatitis (>6mo)

A

B C D

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14
Q

hep A transmission

A

fecal-oral route

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15
Q

hep A presentation

A
less severe in kids
prodromal phase (fever) --> icteric phase
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16
Q

diagnosis of acute vs recovered hep a

A

acute- IgM

past exposure- IgG

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17
Q

prognosis of hep A

A

self-limiting, usu recover w.i wks

mortality is low, fulminant hep uncommon

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18
Q

hep B transmission

A

blood, sex, perinatal

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19
Q

HBsAg

A

surface antigen

only positive in acute or chronic (infxn present)

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20
Q

HBsAb

A

surface antibody
only positive if immunized or resolved infxn
not in current infxn

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21
Q

HBcAb

A

core antibody
IgM (acute)
IgG (chronic or resolved)
NEVER present in immunized

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22
Q

HBeAg

A

envelope antigen

in acute or chronic replicative (inc infectivity, higher chance of developing chronic)

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23
Q

HBeAb

A

envelope antibody

only in chronic non replicative (dec infectivity)

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24
Q

HBV DNA

A

active replication

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25
tx of acute HBV
supportive
26
tx of chronic HBV
alpha-interferon 2b, lamivudine, adefovir, tenofovir, entecavir
27
HBV vaccine is CI if...
allergic to bakers yeast
28
hepatitis E transmission
fecal-oral route, waterborne, pigs (raw meat)
29
tx of hep e
none- self-limiting
30
who has the highest mortality rate when infected w hep e
3rd trimester pregnant moms - inc risk of fulminant
31
hirschprungs disease patho
congenital absence of ganglion cells d/t neural crest migration failure --> functional obstruction d/t failure of relaxation
32
where is hirschsprungs MC
distal colon + rectum
33
when should meconium be passed
w.i 48hrs
34
hirschsprungs presentation
no mec in 48hrs bilious vomiting abd distention FTT
35
hirschsprungs dz can lead to what
enterocolotiis- V/D, signs of toxic megacolon
36
hirschsprungs screening test
elevated pressure (anorectal manometry)
37
what can be see on contrast enema in pt w hirschsprungs
transition zone- caliber changes
38
what do you see on AXR in pt w hirschsprungs
dec or absent air in rectum, dilated bowel loops | NONSPECIFIC
39
what is the definitive diagnostic for hirschsprungs
rectal bx
40
what is the treatment for hirschsprungs
surgery
41
in what populations is hirschsprungs more common
males | down syndrome
42
indirect vs direct inguinal hernia causes
indirect- congenital patent process vaginalis | direct- weak floor of inguinal canal
43
where are indirect vs direct inguinal hernias located
indirect- lateral to inferior epigastric artery | direct- medial
44
which type of inguinal hernia is MC in young kids
indirect
45
how do you tell the difference btw strangulated and incarcerated inguinal hernia
incarcerated- painful + irreducible, +/- n/v | strangulated- systemic toxicity, ischemia
46
tx of inguinal hernia
surgery | emergent if strangulated
47
what is hesselbachs triangle
``` RIP rectus abdominus (medial), epigastric vessels (lateral), poupart's ligament (inferior) ```
48
when is intussusception MC
males, 6-18mo
49
where is intussusception MC
ileocolic jxn
50
what are lead points for intussusception
``` meckel diverticulum enlarged mesenteric LN hyperplasia of peyer's patches benign/malignant tumor submucosal hematoma (HSP) foreign body ```
51
triad of sx of intussusception
vomiting, colicky abd pain, blood in stool (currant jelly) | +/-lethargy
52
what is dance's sign
in intussusception- sausage-shaped mass in RUQ/hypochondrium + empty RLQ
53
dx of intussusception + tx
barium contrast enema (dx + tx), air insufflation hydrate +/- surgery
54
if bili is increased w/o increased LFTs what should you suspect
familial bili disorder
55
path of dubin-johnson vs crigler-najjar syndromes
both hereditary DJ- conjugated (direct) hyperbili d/t decreased hepatocyte excretion CN- unconjugated (indirect) hyperbili d/t UGT deficiency
56
what is UGT
glucuronosyltransferase - enzyme converts indirect bili --> direct bili for excretion
57
type I vs type II crigler-najjar syndrome
``` type I- no UGT (more severe) type II (arias syndrome)- very little UGT ```
58
presentation of dubin-johnson vs crigler-najjar (I+II) syndromes
DJ- usu asx; may have mild icterus + constitutional sx CN I- neonatal jaundice w severe progression in 2nd week --> kernicterus --> hypotonia, deaf, lethargic, oculomotor palsy; death usu by 15mo CN II- usu asx
59
diagnosis of dubin-johnson vs crigler-najjar syndromes
DJ- inc direct, dark liver!!! (on bx), normal LFTs | CN- inc indirect, normal LFTs
60
how can you tell between crigler-najjar type I + II
bili >20 = type I
61
dubin johnson tx
none needed
62
crigler-najjar tx
type I- phototx, plasmapheresis if acute elevation, liver transplant (definitive) type II- usu none needed, can use phenobarbital to inc UGT
63
lactose intolerance patho
intolerance to milk sugar (lactose) | transient after gastroenteritis or in kids w celiac dz d/t vilous atrophy (dec lactose in brush border)
64
lactose intolerance sx
``` inc gas, abd distention watery diarrhea (non-bloody, non-mucous) ```
65
test of choice for lactose intolerance
hydrogen breath test - positive = LI
66
what type of diets are likely to cause niacin deficiency
high in corn
67
what is niacin
B3
68
sx of niacin deficiency
pellagra (3Ds- diarrhea, dementia, dermatitis)
69
what age + gender is most likely to develop pyloric stenosis
3-6wks old (rare after 12wks) | males
70
sx of pyloric stenosis
projectile NONBILIOUS vomiting after feeds w hunger right after palpable pyloric olive poor wt gain visible peristaltic waves
71
what is the preferred imaging for pyloric stenosis
ultrasound- thickened stomach muscle
72
what is the caterpillar sign
seen in pyloric stenosis on KUB- distended hypertrophic stomach
73
tx of pyloric stenosis
pyloromyotomy | fluid resuscitation PRN
74
umbilical hernia patho + tx
failure of fibromuscular ring closure | surgery if >5yo
75
vitamin A functions
``` vision immune embryo development hematopoiesis skin + cell health ```
76
sources of vitamin A
kidney, liver, egg yolk, butter, green leafy veggies
77
sx of vitamin A deficiency
vision- night blindness, xeropthlamia impaired immunity (poor healing), dry skin, poor growth, taste loss, squamous metaplasia (conjunctiva, respiratory epithelium, urinary tract) bitot's spots
78
what are bitot's spots
in vit a def: white spots on conjunctiva D/T squamous metaplasia of corneal epithelium
79
excess vit a can cause
teratogenic, alopecia, ataxia, visual changes, skin disorders, hepatotox
80
vitamin C sources
raw citrus, green veggies
81
sx of vitamin C deficiency
scurvy! - 3 Hs = hyperkeratosis (follicular papillose surrounded by hemorrhage), hemorrhage (vascular fragility, recurrent bleeding in gums, skin, joints, impaired healing), hematologic (anemia, glossitis, malaise, weakness, inc bleeding time)
82
sources of vitamin D
fortified milk + sun | babies get from mom if breast fed, formula supplemented
83
sx of vitamin d def
rickets (kids) | osteomalacia (adults)
84
tx for vit d deficiency
ergocalciferol
85
rickets
softening of bones, bowing of limbs, fxs, costochondral thickening (rachitic rosary), dental problems, music weakness, development delays